Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Selena Milicevic Sephton"'
Autor:
Nicolas Nicastro, Negin Holland, George Savulich, Stephen F. Carter, Elijah Mak, Young T. Hong, Selena Milicevic Sephton, Tim D. Fryer, Franklin I. Aigbirhio, James B. Rowe, John T. O’Brien
Publikováno v:
European Journal of Hybrid Imaging, Vol 4, Iss 1, Pp 1-7 (2020)
Abstract Objective Dementia with Lewy bodies (DLB) is a common cause of dementia, but atrophy is mild compared to Alzheimer’s disease. We propose that DLB is associated instead with severe synaptic loss, and we test this hypothesis in vivo using po
Externí odkaz:
https://doaj.org/article/635372aa80de47148e5ac5852312c09b
Publikováno v:
Pharmaceuticals, Vol 11, Iss 1, p 24 (2018)
The Sonogashira cross-coupling, a key step in the syntheses of the mGlu5 antagonists MMPEP and MTEP, provided an improved three-step method for the preparation of MMPEP in 62% overall yield. Using Spartan molecular modeling kit an explanation for the
Externí odkaz:
https://doaj.org/article/a4994ae8d3594021af31130c1afb9254
Autor:
Selena Milicevic Sephton, Patrick Dennler, Dominique S. Leutwiler, Linjing Mu, Roger Schibli, Stefanie D. Krämer, Simon M. Ametamey
Publikováno v:
CHIMIA, Vol 66, Iss 4 (2012)
Involvement of metabotropic glutamate receptor subtype 5 (mGluR5) in physiological and pathophysiological processes in the brain has been demonstrated, and hence mGluR5 has emerged as an important drug target. [11C]-ABP688 is clinically the most succ
Externí odkaz:
https://doaj.org/article/de6c5f8757e646eebffcefc55dcb1dd0
Autor:
Maura Malpetti, P. Simon Jones, Thomas E. Cope, Negin Holland, Michelle Naessens, Matthew A. Rouse, Timothy Rittman, George Savulich, David J. Whiteside, Duncan Street, Tim D. Fryer, Young T. Hong, Selena Milicevic Sephton, Franklin I. Aigbirhio, John T. O′Brien, James B. Rowe
Publikováno v:
Annals of Neurology. 93:142-154
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2bf702251ce310d8158040eaba4e645
https://doi.org/10.1002/ana.26543
https://doi.org/10.1002/ana.26543
Autor:
Nisha K. Ramakrishnan, Helen M. Betts, Selena Milicevic Sephton, Xiaoyun Zhou, David J. Williamson, Stephen Sawiak, Franklin I. Aigbirhio
Publikováno v:
Nuclear Medicine and Biology. :71-77
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49fd4436ef3d879406f19db272bb8dfc
https://doi.org/10.1016/j.nucmedbio.2022.09.003
https://doi.org/10.1016/j.nucmedbio.2022.09.003
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::559ad93da2bde7b670246e11db0e85e4
https://doi.org/10.1002/jlcr.4029
https://doi.org/10.1002/jlcr.4029
Autor:
Maura Malpetti, P Simon Jones, Thomas E Cope, Negin Holland, Michelle Naessens, Matthew A Rouse, George Savulich, Tim D Fryer, Young T Hong, Selena Milicevic‐Sephton, Franklin I Aigbirhio, John T O'Brien, James B Rowe
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::060c93c156e229cdac77f9e61d9cf649
https://doi.org/10.1002/alz.061706
https://doi.org/10.1002/alz.061706
Publikováno v:
Handbook of Radiopharmaceuticals
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9d18edac35d6f9fc43bc40f4548e63c
https://doi.org/10.1002/9781119500575.ch7
https://doi.org/10.1002/9781119500575.ch7
Autor:
Roido Manavaki, Frank H. Hezemans, Young T. Hong, James B. Rowe, George Savulich, Maura Malpetti, Tim D. Fryer, John T. O'Brien, Julie Wiggins, Jonathan P. Coles, Selena Milicevic Sephton, Istvan Boros, Negin Holland, P. Simon Jones, Franklin I. Aigbirhio
Publikováno v:
Mov Disord
BACKGROUND: Synaptic loss is a prominent and early feature of many neurodegenerative diseases. OBJECTIVES: We tested the hypothesis that synaptic density is reduced in the primary tauopathies of progressive supranuclear palsy (PSP) (Richardson's synd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59a715f5218e0d50acf99cde8d81dd4d
https://doi.org/10.1002/mds.28188
https://doi.org/10.1002/mds.28188
Automated radiosynthesis of [11 C]UCB-J for imaging synaptic density by positron emission tomography
Autor:
Franklin I. Aigbirhio, Lei Li, Joseph J. Russell, Aniruddha Doke, Istvan Boros, Selena Milicevic Sephton, Tünde Miklovicz
Publikováno v:
Journal of Labelled Compounds & Radiopharmaceuticals
An automated radiosynthesis of carbon-11 positron emission tomography radiotracer [11 C]UCB-J for imaging the synaptic density biomarker synaptic vesicle glycoprotein SV2A was established using Synthra RNPlus synthesizer. Commercially available trifl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29967573be34017a7b046adcd8ff9b18
https://doi.org/10.1002/jlcr.3828
https://doi.org/10.1002/jlcr.3828