Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Selena M Sagan"'
Autor:
Sana Naderi, Peter E Chen, Carmen Lia Murall, Raphael Poujol, Susanne Kraemer, Bradley S Pickering, Selena M Sagan, B Jesse Shapiro
Publikováno v:
eLife, Vol 12 (2023)
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a generalist virus, infecting and evolving in numerous mammals, including captive and companion animals, free-ranging wildlife, and humans. Transmission among non-human species poses a r
Externí odkaz:
https://doaj.org/article/68a2de7dd37e4c4688f9de73f9fbbfd2
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 7, p e0009638 (2021)
BackgroundThe leishmaniases are a group of sandfly-transmitted diseases caused by species of the protozoan parasite, Leishmania. With an annual incidence of 1 million cases, 1 billion people living in Leishmania-endemic regions, and nearly 30,000 dea
Externí odkaz:
https://doaj.org/article/c965aa07ffae4395bd5586ff60a84b66
Autor:
Jasmin Chahal, Luca FR Gebert, Hin Hark Gan, Kristin C Gunsalus, Ian J MacRae, Selena M Sagan
Publikováno v:
Proceedings, Vol 50, Iss 1, p 131 (2020)
Hepatitis C virus (HCV) is a positive-sense RNA virus that interacts with a human-liver-specific microRNA, termed miR-122. miR-122 binds to two sites in the 5' untranslated region (UTR) of the viral genome, and this interaction promotes HCV RNA accum
Externí odkaz:
https://doaj.org/article/d0f47fc2e8ad4b3583533ca6fbaf168d
Autor:
Ryan D Pardy, Maaran M Rajah, Stephanie A Condotta, Nathan G Taylor, Selena M Sagan, Martin J Richer
Publikováno v:
PLoS Pathogens, Vol 13, Iss 2, p e1006184 (2017)
Zika virus (ZIKV) is an emerging arbovirus of the Flaviviridae family. Although ZIKV infection is typically mild and self-limiting in healthy adults, infection has been associated with neurological symptoms such as Guillain-Barré syndrome, and a cau
Externí odkaz:
https://doaj.org/article/27737fbe6caf4c378de52f7d059680ef
Autor:
Sonya A MacParland, Marc Bilodeau, Jason Grebely, Julie Bruneau, Curtis Cooper, Marina Klein, Selena M Sagan, Norma Choucha, Louise Balfour, Frank Bialystok, Mel Krajden, Jennifer Raven, Eve Roberts, Rodney Russell, Michael Houghton, D Lorne Tyrrell, Jordan J Feld
Publikováno v:
Canadian Journal of Gastroenterology and Hepatology, Vol 28, Iss 9, Pp 481-487 (2014)
Hepatitis C virus (HCV) currently infects approximately 250,000 individuals in Canada and causes more years of life lost than any other infectious disease in the country. In August 2011, new therapies were approved by Health Canada that have achieved
Externí odkaz:
https://doaj.org/article/2476bb3e96734802921ca6a8e3bc7b10
Autor:
Jason Grebely, Marc Bilodeau, Jordan J Feld, Julie Bruneau, Benedikt Fischer, Jennifer F Raven, Eve Roberts, Norma Choucha, Rob P Myers, Selena M Sagan, Joyce A Wilson, Frank Bialystok, D Lorne Tyrrell, Michael Houghton, Mel Krajden, on behalf of the National CIHR Research Training Program in Hepatitis C
Publikováno v:
Canadian Journal of Gastroenterology, Vol 27, Iss 11, Pp 627-632 (2013)
In Canada, hepatitis C virus (HCV) infection results in considerable morbidity, mortality and health-related costs. Within the next three to 10 years, it is expected that tolerable, short-duration (12 to 24 weeks) therapies capable of curing >90% of
Externí odkaz:
https://doaj.org/article/57253eb307e94ad1b36afc858508d059
Autor:
Selena M. Sagan, Stephanie C. Weber
Publikováno v:
Trends in Biochemical Sciences. 48:229-243
Viruses compartmentalize their replication and assembly machinery to both evade detection and concentrate the viral proteins and nucleic acids necessary for genome replication and virion production. Accumulating evidence suggests that diverse RNA and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2963b7c0a91b015ebbd20544835a9c4b
https://doi.org/10.1016/j.tibs.2022.09.008
https://doi.org/10.1016/j.tibs.2022.09.008
Publikováno v:
Nucleic Acids Research. 51:2447-2463
Efficient hepatitis C virus (HCV) RNA accumulation is dependent upon interactions with the human liver-specific microRNA, miR-122. MiR-122 has at least three roles in the HCV life cycle: it acts as an RNA chaperone, or ‘riboswitch’, allowing form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ab1f8a34e7eb027d7bf806c633df804
https://doi.org/10.1093/nar/gkad094
https://doi.org/10.1093/nar/gkad094
Autor:
Sana Naderi, Peter E. Chen, Carmen Lía Murall, Raphael Poujol, Susanne Kraemer, Bradley S. Pickering, Selena M. Sagan, B. Jesse Shapiro
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a generalist virus, infecting and evolving in numerous mammals, including captive and companion animals, free-ranging wildlife, and humans. Transmission among non-human species poses a r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::353fd1667428f2f8a71cec028891a547
https://doi.org/10.1101/2022.06.02.494559
https://doi.org/10.1101/2022.06.02.494559
