Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Selena, Nola"'
Autor:
Caterina Virginio, Laura Aldegheri, Selena Nola, Daniela Brodbeck, Laurent Brault, Luca F. Raveglia, Alessio Barilli, Mark Sabat, Richard Myers
Publikováno v:
SLAS Discovery, Vol 27, Iss 1, Pp 55-64 (2022)
Transient Receptor Potential Melastatin 5 (TRPM5) is an intracellular calcium-activated cation-selective ion channel expressed in a variety of cell types. Dysfunction of this channel has recently been implied in a range of disease states including di
Externí odkaz:
https://doaj.org/article/4cf64e986b4845aa93cac6e858d386ee
Autor:
Ezio Bettini, Stephen M. Stahl, Sara De Martin, Andrea Mattarei, Jacopo Sgrignani, Corrado Carignani, Selena Nola, Patrizia Locatelli, Marco Pappagallo, Charles E. Inturrisi, Francesco Bifari, Andrea Cavalli, Andrea Alimonti, Luca Pani, Maurizio Fava, Sergio Traversa, Franco Folli, Paolo L. Manfredi
Publikováno v:
Pharmaceuticals, Vol 15, Iss 8, p 997 (2022)
Excessive Ca2+ currents via N-methyl-D-aspartate receptors (NMDARs) have been implicated in many disorders. Uncompetitive NMDAR channel blockers are an emerging class of drugs in clinical use for major depressive disorder (MDD) and other neuropsychia
Externí odkaz:
https://doaj.org/article/a9489daf59de4062bfa561e5de1336f9
Autor:
Raveglia Luca Francesco, Richard M. Myers, Caterina Virginio, Mark Sabat, Daniela Brodbeck, Laurent Brault, Selena Nola, Alessio Barilli, Laura Aldegheri
Publikováno v:
SLAS Discovery. 27:55-64
Transient Receptor Potential Melastatin 5 (TRPM5) is an intracellular calcium-activated cation-selective ion channel expressed in a variety of cell types. Dysfunction of this channel has recently been implied in a range of disease states including di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feac2b5c5ecd8e0a04d427042b52264e
https://doi.org/10.1016/j.slasd.2021.10.004
https://doi.org/10.1016/j.slasd.2021.10.004
Autor:
Daniela Pompilio, Sabrina Tassini, Laura Piccoli, Alessio Barilli, Aldo Feriani, Daniela Brodbeck, Laura Castelletti, Raveglia Luca Francesco, Laurent Brault, Iain Lingard, Laura Aldegheri, Federica Bianchi, Mark Sabat, Richard M. Myers, Caterina Virginio, Selena Nola, Cristian Salvagno
Publikováno v:
Journal of Medicinal Chemistry. 64:5931-5955
Transient receptor potential cation channel subfamily M member 5 (TRPM5) is a nonselective monovalent cation channel activated by intracellular Ca2+ increase. Within the gastrointestinal system, TRPM5 is expressed in the stoma, small intestine, and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::276f841154741494c801408c590e8d10
https://doi.org/10.1021/acs.jmedchem.1c00065
https://doi.org/10.1021/acs.jmedchem.1c00065
Autor:
Alessio, Barilli, Laura, Aldegheri, Federica, Bianchi, Laurent, Brault, Daniela, Brodbeck, Laura, Castelletti, Aldo, Feriani, Iain, Lingard, Richard, Myers, Selena, Nola, Laura, Piccoli, Daniela, Pompilio, Luca F, Raveglia, Cristian, Salvagno, Sabrina, Tassini, Caterina, Virginio, Mark, Sabat
Publikováno v:
Journal of medicinal chemistry. 64(9)
Transient receptor potential cation channel subfamily M member 5 (TRPM5) is a nonselective monovalent cation channel activated by intracellular Ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d619050999d16fbf323a8d84594fd590
https://pubmed.ncbi.nlm.nih.gov/33890770
https://pubmed.ncbi.nlm.nih.gov/33890770
Autor:
Marco Pappagallo, Sergio Traversa, Stephen M. Stahl, Charles E. Inturrisi, Andrea Mattarei, Paolo L Manfredi, Ezio Bettini, Sara De Martin, Selena Nola
Publikováno v:
Biological Psychiatry. 89:S198-S199
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::840ed28aa09630fc5e120be923e56f83
https://doi.org/10.1016/j.biopsych.2021.02.503
https://doi.org/10.1016/j.biopsych.2021.02.503
Autor:
Aldo Feriani, Laura Zonzini, Laura Castelletti, Selena Nola, Michele Dal Cin, Teresa Semeraro, Sylvie Gehanne, Silvia Tomelleri, Filippo Visentini, Palmina Cavallini, Susanna Cremonesi, Annalisa Pellacani, Anna Sava, Alessia Bacchi, Andrea Wong, Simone Braggio, Luca Tarsi, Mahmud Kajbaf, Paolo Cavanni, Elisabetta Perdona, Christian Heidbreder, Luciano Marchiò, Beatrice Oliosi, Fabrizio Micheli
Publikováno v:
Journal of Medicinal Chemistry. 59:8549-8576
A novel series of 1,2,4-triazolyl 5-azaspiro[2.4]heptanes with high affinity and selectivity at the dopamine (DA) D3 receptor (D3R) is described. Some of these compounds also have high selectivity over the hERG channel and were characterized with res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e92639ff81d14ff2d424ab7f16b988a
https://doi.org/10.1021/acs.jmedchem.6b00972
https://doi.org/10.1021/acs.jmedchem.6b00972