Zobrazeno 1 - 10
of 154
pro vyhledávání: '"Sekhar P Reddy"'
Autor:
Narsa M Reddy, Haranatha R Potteti, Suryanarayana Vegiraju, Hsin-Jou Chen, Chandra Mohan Tamatam, Sekhar P Reddy
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0129676 (2015)
Lung epithelial and endothelial cell death accompanied by inflammation contributes to hyperoxia-induced acute lung injury (ALI). Impaired resolution of ALI can promote and/or perpetuate lung pathogenesis, including fibrosis. Previously, we have shown
Externí odkaz:
https://doaj.org/article/400a769564f44535908537374936e1fc
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41611 (2012)
The Fra-1/AP-1 transcription factor plays a key role in tumor epithelial cell progression; however, its role in pathogenic lung fibrosis remains unclear. In the present study, using a genetic approach (Fra-1 deficient mice), we have demonstrated a no
Externí odkaz:
https://doaj.org/article/7ffa7296682748198adb575e66c93502
Autor:
Shreeram C Nallar, Limei Lin, Varsha Srivastava, Padmaja Gade, Edward R Hofmann, Hafiz Ahmed, Sekhar P Reddy, Dhananjaya V Kalvakolanu
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24082 (2011)
We have recently isolated novel IFN-inducible gene, Gene associated with Retinoid-Interferon-induced Mortality-1 (GRIM-1), using a genetic technique. Moderate ectopic expression of GRIM-1 caused growth inhibition and sensitized cells to retinoic acid
Externí odkaz:
https://doaj.org/article/a6bbe6d88a6946c99961188ff56f603f
Autor:
Mahendra Damarla, Emile Hasan, Adel Boueiz, Anne Le, Hyun Hae Pae, Calypso Montouchet, Todd Kolb, Tiffany Simms, Allen Myers, Usamah S Kayyali, Matthias Gaestel, Xinqi Peng, Sekhar P Reddy, Rachel Damico, Paul M Hassoun
Publikováno v:
PLoS ONE, Vol 4, Iss 2, p e4600 (2009)
Mechanical ventilation, a fundamental therapy for acute lung injury, worsens pulmonary vascular permeability by exacting mechanical stress on various components of the respiratory system causing ventilator associated lung injury. We postulated that M
Externí odkaz:
https://doaj.org/article/aaddede4d200406bbc47ea2f70c651a2
T Cell Nrf2/Keap1 Gene Editing Using CRISPR/Cas9 and Experimental Kidney Ischemia-Reperfusion Injury
Autor:
Johanna T. Kurzhagen, Sanjeev Noel, Kyungho Lee, Mohanraj Sadasivam, Sepideh Gharaie, Aparna Ankireddy, Sul A. Lee, Andrea Newman-Rivera, Jing Gong, Lois J. Arend, Abdel R.A. Hamad, Sekhar P. Reddy, Hamid Rabb
Publikováno v:
Antioxidants & Redox Signaling. 38:959-973
FRA-1 forms activator protein-1 complexes in association with members of the JUN family and drives gene transcription. FRA-1 has been implicated in the development of airway squamous metaplasia and is frequently overexpressed in squamous cell carcino
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fa32a21c8c2ae374ab1b7a41f61e515
https://doi.org/10.1158/0008-5472.c.6495567
https://doi.org/10.1158/0008-5472.c.6495567
Publikováno v:
IEEE Transactions on Electron Devices; January 2024, Vol. 71 Issue: 1 p223-230, 8p
Autor:
Faiza Kalam, Rand T. Akasheh, Sofia Cienfuegos, Aparna Ankireddy, Kelsey Gabel, Mark Ezpeleta, Shuhao Lin, Chandra M. Tamatam, Sekhar P. Reddy, Bonnie Spring, Seema A. Khan, Krista A. Varady
Publikováno v:
Obesity (Silver Spring, Md.)REFERENCES.
Concerns have been raised regarding the impact of time-restricted eating (TRE) on sex hormones in females. This study examined how TRE affects sex steroids in premenopausal and postmenopausal females.This is a secondary analysis of an 8-week TRE stud
Autor:
Patrick M Noone, Masayuki Yamamoto, Haranatha R. Potteti, Thomas W. Kensler, Narsa M. Reddy, Chandra Mohan Tamatam, Aparna Ankireddy, Sekhar P. Reddy
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports
Bronchopulmonary dysplasia (BPD) is a chronic disease of preterm babies with poor clinical outcomes. Nrf2 transcription factor is crucial for cytoprotective response, whereas Keap1—an endogenous inhibitor of Nrf2 signaling—dampens these protectiv
Autor:
Ramaswamy Ramchandran, Mounica Bandela, Arjun Pennathur, Rama Kamesh Bikkavilli, Sreedevi Avasarala, Long Shuang Huang, Valerian E. Kagan, Xiangdong Zhu, Viswanathan Natarajan, Puttaraju S. Yashaswini, Yulia Y. Tyurina, Anantha Harijith, Prasanth-Kumar Punathil-Kannan, Michelle VanScoyk, Ravi Salgia, Sekhar P. Reddy, Tara Sudhadevi, Robert A. Winn, Sainath R. Kotha
Publikováno v:
J Biol Chem
Lysocardiolipin acyltransferase (LYCAT), a cardiolipin (CL)-remodeling enzyme, is crucial for maintaining normal mitochondrial function and vascular development. Despite the well-characterized role for LYCAT in the regulation of mitochondrial dynamic