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Tumour-associated trypsin inhibitor, carcinoembryonic antigen and acute-phase reactant proteins CRP and alpha 1-antitrypsin in patients with gastrointestinal malignancies

Autor: Solakidi, S Dessypris, A Stathopoulos, GP Androulakis, G and Sekeris, CE

Objectives: Elevated serum tumour-associated trypsin inhibitor (TATI) levels have been observed in association with malignancy or inflammation. The aim of our study was to evaluate the role of TATI in gastric and colorectal cancer. Design and methods

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::b427ee9aae57dd237ecf3707f1ebd1dc
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3084868

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Estrogen receptor alpha gene analysis in osteoporosis and familial osteoporosis

Autor: Fountas, L Anapliotou, M Kominakis, A Sekeris, CE Kassi, E Moutsatsou, P

Estrogens are important determinants of bone mineral density (BMD) mediating their effects via estrogen receptor alpha (ERalpha) and beta (ERbeta). The strong genetic predisposition to osteoporosis, and the fact that alterations in the aminoterminal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::af030546f6f7682ad92ed7b47799dbc7
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3092673

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The dynamic localization of the glucorticoid receptor in rat C6 glioma cell mitochondria

Autor: Koufali, MM Moutsatsou, P Sekeris, CE Breen, KC

Glucocorticoids modify gene expression via the translocation of receptors from the cytosol to the nucleus following agonist-associated receptor activation. In this study, we have characterized mitochondrial glucocorticoid (GR) localization and associ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::9482a2240cb57078bedb626958c55bf6
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3084624

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Application of denaturing gradient gel electrophoresis (DGGE) to screen for mutations of the human glucocorticoid receptor a gene (hGR alpha)

Autor: Tsolakidou, AF Coulocheri, SA Sekeris, CE Moutsatsou, P

Objectives: In a previous publication, we had presented a sensitive method to detect mutations of the segment of the human glucocorticoid. receptor alpha (hGRalpha) gene encoding the ligand binding domain (LBD) and part of the DNA binding domain (DBD

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::b574fd58c15333e9ebc482f6962209f9
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3083740

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Mitochondrial localization of glucocortocoid receptor in glial (Muller) cells in the salamander retina

Autor: Psarra, AMG Bochaton-Piallat, ML Gabbiani, G Sekeris, CE and Tsacopoulos, M

Glucocorticoid hormones regulate the transcription of nuclear genes by way of their receptors. In addition, these hormones modulate mitochondrial gene transcription by mechanisms that remain poorly understood. Using immunofluorescence labeling in iso

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::50ef56e6175301db5382a2c87efa2ae3
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3082917

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Mutation detection of the human glucocorticoid receptor alpha gene area coding for the hormone-binding domain by denaturing gradient gel electrophoresis

Autor: Tsolakidou, AF Coulocheri, SA Sekeris, CE Moutsatsou, P

Mutations in the hormone-binding domain of the human glucocorticoid receptor alpha (hGRalpha) gene have been detected in a variety of glucocorticoid resistance syndromes. Using the denaturing gradient gel electrophoresis technique, we developed a sen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::a26398e256ef9c0a7a1a28fb632ef084
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3081880

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Localization of the glucocorticoid receptor in rat brain mitochondria

Autor: Moutsatsou, P Psarra, AMG Tsiapara, A Paraskevakou, H and Davaris, P Sekeris, CE

The distribution of glucocorticoid receptor in subcellular fractions of brain cortex and hippocampus, two regions rich in glucocorticoid receptor, has revealed its presence in nuclei, cytosol, mitochondria, synaptosomes, and synaptosomal mitochondria

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::2b95f45e2e546a4ffd68af1be90f2f9a
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3054640

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Molecular analysis of estrogen receptor alpha and beta in lupus patients

Autor: Kassi, EN Vlachoyiannopoulos, PG Moutsopoulos, HM Sekeris, CE Moutsatsou, P

Background In female patients with systemic lupus erythematosus (SLE), we identified estrogen receptor ERa, ERb and ERa variant transcripts in peripheral blood mononuclear cells (PBMC). Exon 1 and 2 of ERa gene was subjected to mutation analysis to a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::eecaf383ad3e5bdc74fbdfa7507c7748
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3054333

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Localization of glucocorticoid hormone receptors in mitochondria of human cells

Autor: Scheller, K Sekeris, CE Krohne, G Hock, R Hansen, IA and Scheer, U

Glucocorticoid hormones regulate the transcription of nuclear genes by may of their cognate receptors. In addition, these hormones also modulate mitochondrial gene transcription by mechanisms which are as yet poorly understood. Using immunofluorescen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::56b17a1e389c434b87127d27df9f978b
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3053337

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