Zobrazeno 1 - 10 of 20 pro vyhledávání: '"Sejal Kothadia"'
1
Characterization of Comorbidities Limiting the Recruitment of Patients in Early Phase Clinical Trials
Autor: Miguel Gonzalez Velez, Narjust Duma, Tariq U. Azam, Sejal Kothadia, Joleen M. Hubbard, Ronald S. Go, Thorvardur R. Halfdanarson, Alex A. Adjei, Siddhartha Yadav, Aaron S. Mansfield, Jonas Paludo, Jesus Vera Aguilera, Julian R. Molina
Publikováno v: The Oncologist. 24:96-102
Background Early phase clinical trials evaluate the safety and efficacy of new treatments. The exclusion/inclusion criteria in these trials are usually rigorous and may exclude many patients seen in clinical practice. Our objective was to study the c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eea1388532229ac32d2706ed989799c6
https://doi.org/10.1634/theoncologist.2017-0687
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2
A phase 1 study of neoadjuvant chemotherapy followed by concurrent chemoradiation with gemcitabine, sorafenib, and vorinostat in pancreatic cancer
Autor: Khalid Matin, Emma C. Fields, Andrew Poklepovic, Sejal Kothadia, Sarah W. Gordon, Maciej Kmieciak, Dipankar Bandyopadhyay, Bhaumik Patel, Jennifer Myers, William McGuire, Mary Beth Tombes, Paul Dent, Brian J. Kaplan
Publikováno v: Journal of Clinical Oncology. 39:e16268-e16268
e16268 Background: The multi-kinase inhibitor sorafenib (S) and HDAC inhibitor vorinostat (V) demonstrated synergism against preclinincal pancreatic cancer (PaCa) models. The combination of S & V also potently radiosensitized pancreatic cancer cells
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d57441b4e487d904adcc370f0d1825f5
https://doi.org/10.1200/jco.2021.39.15_suppl.e16268
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3
ARRHYTHMIA IN BONE MARROW TRANSPLANT: WHY WE SHOULD WORRY
Autor: Ahmad Al Turk, Asaad Nakhle, Jieqi Liu, Sejal Kothadia, Umar Jamshed
Publikováno v: Journal of the American College of Cardiology. 73:500
The Bone Marrow Transplant Survivor Study indicates that two-thirds of hematopoietic stem cell transplantation (HSCT) survivors develop a chronic health condition. Arrhythmia has been identified as a complication of HSCT in single-institution reports
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::50c4e61860f7938972cfa4a7e1a14269
https://doi.org/10.1016/s0735-1097(19)31108-8
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4
Carfilzomib Cardiovascular Disease: Use of the Atherosclerotic Cardiovascular Disease Score to Predict Cardiovascular Events in Multiple Myeloma Patients Treated with Carfilzomib
Autor: David S. Siegel, Jieqi Liu, Giselle A. Suero-Abreu, Rima M Panchal, Noa Biran, David H. Vesole, Ricardo D. Parrondo, Sejal Kothadia, Tracy Andrews, Camille Johnson
Publikováno v: Blood. 132:3254-3254
Introduction: In the ASPIRE and ENDEAVOR trials, multiple myeloma (MM) patients treated with carfilzomib (K) had significantly improved progression‐free survival and overall survival compared with standard of care. The incidence of all-grade advers
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dc2542471a43a60b2d179b90c6e4cfff
https://doi.org/10.1182/blood-2018-99-113722
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5
Comprehensive analysis of tumor mutational load, genomic alterations, and PD-L1 status in gastrointestinal cancers using a multiplatform molecular profiling tool
Autor: Giselle A. Suero-Abreu, Ning Dong, Martin Gutierrez, Narjust Duma, Miguel Gonzalez Velez, Sejal Kothadia, Daniel Pievsky, Tracy Ann Proverbs-Singh, Shalini R. Krishnasamy, Umar Sharif Khawaja, Marshall McKenna, Janice Liu
Publikováno v: Journal of Clinical Oncology. 36:93-93
93 Background: Tumor mutational load (TML) has been proposed as a biomarker of responsiveness to novel immune checkpoint inhibitors (ICIs) due its association with increased neoantigen formation and tumor immunogenicity. Gastrointestinal cancers (GIC
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2b1ff235b6883b2ca66bde43a05d5ed3
https://doi.org/10.1200/jco.2018.36.5_suppl.93
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6
Comparison of palliative care for lung cancer patients (pts) at two Veteran Affairs Medical Centers
Autor: Sejal Kothadia, David Klein, Stephanie Hwa, Victor T. Chang, Ellen Olson, Yeun-Hee Anna Park, Zhen Wang, Fengming Zhong, Andrea Leaf, Sarah Lee
Publikováno v: Journal of Clinical Oncology. 35:e21621-e21621
e21621 Background: Palliative and end of life care is essential for lung cancer pts. We examined palliative care delivery for lung cancer pts at 2 VA medical centers. Methods: In an IRB approved protocol, we reviewed medical records of matched pts di
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::be22a613eed2f704305a5a80c6f20ab2
https://doi.org/10.1200/jco.2017.35.15_suppl.e21621
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7
A comparison of liver cancer and lung cancer patients at two Veteran Affairs Medical Centers
Autor: Yucai Wang, Sejal Kothadia, Sarah Lee, Yeun-Hee Anna Park, Zhen Wang, Ellen Olson, Victor T. Chang, Fengming Zhong, Andrea Leaf, Stephanie Hwa, David Klein
Publikováno v: Journal of Clinical Oncology. 35:e21642-e21642
e21642 Background: Little is known about palliative care for liver cancer. In this study, we examined palliative care for liver cancer and lung cancer patients. Methods: In an IRB approved protocol, we reviewed medical records of patients diagnosed w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5a8bf07409c5c4c9b8149f4eb0b92b73
https://doi.org/10.1200/jco.2017.35.15_suppl.e21642
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8
Genomic-directed therapy of gastrointestinal cancers by comprehensive genomic profile (CGP): Clinical and genomic characteristics at the John Theurer Cancer Center (JTCC)
Autor: Sejal Kothadia, Andrew Jennis, Martin Gutierrez, Narjust Duma, Ricardo Daniel Parrondo, Veronica Mariotti, Valentina Jaramillo Restrepo, Beth Boseski, Pablo Lopez-Zertuche, Miguel Gonzalez Velez
Publikováno v: Journal of Clinical Oncology. 35:803-803
803 Background: The routine use of comprehensive genomic profiling (CGP) has led to better genomic characterization, more personalized treatments and higher enrollment in clinical trials for many solid cancers. The aim of this study was to evaluate t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3251e395cba894cd5ab2e3c70f280ee7
https://doi.org/10.1200/jco.2017.35.4_suppl.803
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9
Analysis of clinical and research implications of expanding next-generation sequencing (NGS) libraries in the treatment options of gastrointestinal cancers in a large cancer center
Autor: Veronica Mariotti, Beth Boseski, Miguel Gonzalez Velez, Sejal Kothadia, Ricardo Daniel Parrondo, Valentina Jaramillo Restrepo, Martin Gutierrez, Narjust Duma, Pablo Lopez-Zertuche, Andrew Jennis
Publikováno v: Journal of Clinical Oncology. 35:774-774
774 Background: The use of next-generation sequencing (NGS) in clinical practice has increased the therapeutic options for many cancers. Multiple NGS assays are now commercially used. The genomic libraries used by these assays are continuously being
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::19139a8dfa78507114df0e0211a04e87
https://doi.org/10.1200/jco.2017.35.4_suppl.774
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