Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Sejal J Patel"'
Publikováno v:
Journal of the Serbian Society for Computational Mechanics. 11:69-81
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67f2d15ba6015f9ad9e9d1c0c5c965f3
https://doi.org/10.24874/jsscm.2017.11.01.07
https://doi.org/10.24874/jsscm.2017.11.01.07
Publikováno v:
Advances in Medical Education and Practice
Sejal J Patel,1 Kathi J Kemper,2 Joseph P Kitzmiller3 1College of Public Health, The Ohio State University, 2Center for Integrative Health and Wellness, The Ohio State Wexner University Medical Center, 3Department of Biological Chemistry and Pharmaco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ace313df772aaae3f5947d6db0f3dc9
https://doi.org/10.2147/amep.s138572
https://doi.org/10.2147/amep.s138572
Autor:
Gunamani Deheri, Sejal J. Patel
Publikováno v:
Indian Journal of Materials Science. 2015:1-9
This investigation analyzes the performance of a magnetic fluid based squeeze film for a sphere in a rough spherical seat with slip velocity. The slip model of Beavers and Joseph has been deployed to study the effect of velocity slip while the stocha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7ea4bacbeb58a61a34e5830984d0254
https://doi.org/10.1155/2015/159698
https://doi.org/10.1155/2015/159698
Autor:
Feng Gu, Mee Kian Poh, Wai Yee Phong, Subhash G. Vasudevan, Edgar Jacoby, Olivier Heudi, Hao Ying Xu, Deana Jaber, Sejal J. Patel, Ngai Ling Ma, Ranga Rao, Wouter Schul, Eric Vangrevelinghe, Thomas H. Keller, Qing-Yin Wang
Publikováno v:
Antimicrobial Agents and Chemotherapy. 53:1823-1831
The incidence of dengue fever epidemics has increased dramatically over the last few decades. However, no vaccine or antiviral therapies are available. Therefore, the need for safe and effective antiviral drugs has become imperative. The entry of den
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::860f8efa995a625b6264862dabe5459c
https://doi.org/10.1128/aac.01148-08
https://doi.org/10.1128/aac.01148-08
Autor:
Ken Yamada, Hyi-Man Park, Dean F Rigel, Keith DiPetrillo, Erin J Whalen, Anthony Anisowicz, Michael Beil, James Berstler, Cara Emily Brocklehurst, Debra A Burdick, Shari L Caplan, Michael P Capparelli, Guanjing Chen, Wei Chen, Bethany Dale, Lin Deng, Fumin Fu, Norio Hamamatsu, Kouki Harasaki, Tracey Herr, Peter Hoffmann, Qi-Ying Hu, Waan-Jeng Huang, Neeraja Idamakanti, Hidetomo Imase, Yuki Iwaki, Monish Jain, Jey Jeyaseelan, Mitsunori Kato, Virendar K Kaushik, Darcy Kohls, Vidya Kunjathoor, Daniel LaSala, Jongchan Lee, Jing Liu, Yang Luo, Fupeng Ma, Ruowei Mo, Sarah Mowbray, Muneto Mogi, Flavio Ossola, Pramod Pandey, Sejal J Patel, Swetha Raghavan, Bahaa Salem, Yuka H Shanado, Gary M Trakshel, Gordon Turner, Hiromichi Wakai, Chunhua Wang, Stephen Weldon, Jennifer B Wielicki, Xiaoling Xie, Lingfei Xu, Yukiko I Yagi, Kayo Yasoshima, Jianning Yin, David Yowe, Ji-Hu Zhang, Gang Zheng, Lauren Monovich
Publikováno v:
Nature chemical biology. 12(11)
The With-No-Lysine (K) (WNK) kinases play a critical role in blood pressure regulation and body fluid and electrolyte homeostasis. Herein, we introduce the first orally bioavailable pan-WNK-kinase inhibitor, WNK463, that exploits unique structural fe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78087a9853125909a6b388fbc86c95c9
https://pubmed.ncbi.nlm.nih.gov/27595330
https://pubmed.ncbi.nlm.nih.gov/27595330
Autor:
Subhash G. Vasudevan, Wai-Ling Chan, Ngai Ling Ma, Siew Pheng Lim, Zheng Yin, Thomas H. Keller, Viral Patel, Weiling Wang, Sejal J. Patel, John E. Knox, David Beer, Xinyi Ngew, K. R. Ranga Rao, Gang Wang
Publikováno v:
Journal of Medicinal Chemistry. 49:6585-6590
A series of inhibitors related to the benzoyl-norleucine-lysine-arginine-arginine (Bz-nKRR) tetrapeptide aldehyde was synthesized. When evaluated against the West Nile virus (WNV) NS3 protease, the measured IC(50) ranges from approximately 1 to 200 m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c538ef3a9528a20492e59b873f032e6f
https://doi.org/10.1021/jm0607606
https://doi.org/10.1021/jm0607606
Autor:
Zheng Yin, Thomas H. Keller, Subhash G. Vasudevan, Gang Wang, Siew Pheng Lim, Viral Patel, Weiling Wang, David Beer, Sejal J. Patel, K. R. Ranga Rao, Jenefer Alam, Xinyi Ngew, Wai-Ling Chan, Duraiswamy Athisayamani Jeyaraj
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 16:36-39
Substrate-based tetrapeptide inhibitors with various warheads were designed, synthesized, and evaluated against the Dengue virus NS3 protease. Effective inhibition was achieved by peptide inhibitors with electrophilic warheads such as aldehyde, trifl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b31e17c267fca1ad851cc9086233203
https://doi.org/10.1016/j.bmcl.2005.09.062
https://doi.org/10.1016/j.bmcl.2005.09.062
Autor:
Sejal J, Patel, Timothy F, Jamison
Publikováno v:
Angewandte Chemie International Edition. 43:3941-3944
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ce9cafcb30b51664707fe0f918c8526
https://doi.org/10.1002/anie.200460044
https://doi.org/10.1002/anie.200460044
Autor:
Ngai Ling Ma, Aruna Sampath, Zheng Yin, Subhash G. Vasudevan, Qing Yin Wang, Sejal J. Patel, John E. Knox, Siew Pheng Lim, Yen Liang Chen, Thomas H. Keller
Publikováno v:
New Treatment Strategies for Dengue and Other Flaviviral Diseases: Novartis Foundation Symposium 277
With the incidence of dengue fever increasing all over the world, there is an urgent need for therapies. While drug discovery for any disease is a long and difficult process with uncertain success, dengue fever poses an additional complication in tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb218b6fe6408713b6913b0b9a2efdeb
https://doi.org/10.1002/0470058005.ch8
https://doi.org/10.1002/0470058005.ch8
Autor:
Kristina Löhr, Sejal J. Patel, John E. Knox, Thomas H. Keller, Subhash G. Vasudevan, Gang Wang, Zheng Yin, Ngai Ling Ma, Wai-Ling Chan, Weiling Wang, Wai Yee Phong, K. R. Ranga Rao, Aruna Sampath, Siew Pheng Lim
Publikováno v:
The Journal of general virology. 88(Pt 8)
A recombinant form of yellow fever virus (YFV) NS3 protease, linked via a nonapeptide to the minimal NS2B co-factor sequence (CF40-gly-NS3pro190), was expressed in Escherichia coli and shown to be catalytically active. It efficiently cleaved the fluo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a364c842c557bea4dee17a6d0cf9c0d4
https://pubmed.ncbi.nlm.nih.gov/17622626
https://pubmed.ncbi.nlm.nih.gov/17622626