Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Seiya Tokunaga"'
Autor:
Shuo-Chien Ling, Somasish Ghosh Dastidar, Seiya Tokunaga, Wan Yun Ho, Kenneth Lim, Hristelina Ilieva, Philippe A Parone, Sheue-Houy Tyan, Tsemay M Tse, Jer-Cherng Chang, Oleksandr Platoshyn, Ngoc B Bui, Anh Bui, Anne Vetto, Shuying Sun, Melissa McAlonis-Downes, Joo Seok Han, Debbie Swing, Katannya Kapeli, Gene W Yeo, Lino Tessarollo, Martin Marsala, Christopher E Shaw, Greg Tucker-Kellogg, Albert R La Spada, Clotilde Lagier-Tourenne, Sandrine Da Cruz, Don W Cleveland
Publikováno v:
eLife, Vol 8 (2019)
Mutations in coding and non-coding regions of FUS cause amyotrophic lateral sclerosis (ALS). The latter mutations may exert toxicity by increasing FUS accumulation. We show here that broad expression within the nervous system of wild-type or either o
Externí odkaz:
https://doaj.org/article/04213ee8809d4946acefc96cd36ba9b2
Autor:
Martin Marsala, Shuying Sun, Ngoc B. Bui, Tsemay M. Tse, Shuo-Chien Ling, Greg Tucker-Kellogg, Gene W. Yeo, Philippe A. Parone, Hristelina Ilieva, Seiya Tokunaga, Christopher Shaw, Sandrine Da Cruz, Oleksandr Platoshyn, Kenneth Lim, Somasish Ghosh Dastidar, Don W. Cleveland, Clotilde Lagier-Tourenne, Debbie Swing, Joo Seok Han, Albert R. La Spada, Anh Bui, Wan Yun Ho, Lino Tessarollo, Jer-Cherng Chang, Melissa McAlonis-Downes, Sheue-Houy Tyan, Anne P. Vetto, Katannya Kapeli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6336cbcf1decdbc907883e7a0b14a4f7
https://doi.org/10.7554/elife.40811.039
https://doi.org/10.7554/elife.40811.039
Autor:
Kenneth Lim, Shuying Sun, Sandrine Da Cruz, Debbie Swing, Wan Yun Ho, Philippe A. Parone, Ngoc B. Bui, Jer Cherng Chang, Clotilde Lagier-Tourenne, Joo Seok Han, Albert R. La Spada, Hristelina Ilieva, Anh Bui, Melissa McAlonis-Downes, Katannya Kapeli, Don W. Cleveland, Seiya Tokunaga, Greg Tucker-Kellogg, Martin Marsala, Christopher Shaw, Oleksandr Platoshyn, Somasish Ghosh Dastidar, Tsemay M. Tse, Shuo-Chien Ling, Gene W. Yeo, Sheue Houy Tyan, Lino Tessarollo, Anne P. Vetto
Publikováno v:
Autophagy
eLife, Vol 8 (2019)
eLife
eLife, Vol 8 (2019)
eLife
Coding or non-coding mutations in FUS (fused in sarcoma) cause amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). In addition to familial ALS, abnormal aggregates of FUS are present in a portion of FTD and other neurodegenerative
Autor:
Taiji Tsunemi, Don W. Cleveland, Ling T. Guo, Shuo-Chien Ling, Edith Lopez, G. Diane Shelton, Linda Ly, Seiya Tokunaga, Bryce L. Sopher, Gene Hung, C. Frank Bennett, Constanza J. Cortes, Albert R. La Spada
Publikováno v:
Neuron, vol 82, iss 2
SummaryX-linked spinal and bulbar muscular atrophy (SBMA) is characterized by adult-onset muscle weakness and lower motor neuron degeneration. SBMA is caused by CAG-polyglutamine (polyQ) repeat expansions in the androgen receptor (AR) gene. Pathologi
Autor:
Ying Sun, Shuying Sun, Laura Ferraiuolo, Yiyang Zou, Alex Kopelevich, Dara Ditsworth, Clotilde Lagier-Tourenne, Don W. Cleveland, Kevin Drenner, Yin Wang, Melissa McAlonis-Downes, Shuo-Chien Ling, Brian K. Kaspar, Seiya Tokunaga
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 112, iss 50
Ubiquitous expression of amyotrophic lateral sclerosis (ALS)-causing mutations in superoxide dismutase 1 (SOD1) provokes noncell autonomous paralytic disease. By combining ribosome affinity purification and high-throughput sequencing, a cascade of mu
Autor:
Shuo-Chien Ling, Clotilde Lagier-Tourenne, Seiya Tokunaga, Don W. Cleveland, Claudio P. Albuquerque, Huilin Zhou, Joo Seok Han
Publikováno v:
Proceedings of the National Academy of Sciences. 107:13318-13323
Dominant mutations in two functionally related DNA/RNA-binding proteins, trans-activating response region (TAR) DNA-binding protein with a molecular mass of 43 KDa (TDP-43) and fused in sarcoma/translocation in liposarcoma (FUS/TLS), cause an inherit
Autor:
Haiyan Qiu, Gene W. Yeo, Huilin Zhou, Eric J. Huang, Clotilde Lagier-Tourenne, Shuo-Chien Ling, Xiang-Dong Fu, Hairi Li, Kevin Eggan, Don W. Cleveland, Yu Zhou, Seiya Tokunaga, Jinsong Qiu, Anh Bui, Claudio P. Albuquerque, Shuying Sun
Publikováno v:
Nature communications
The RNA-binding protein FUS/TLS, mutation in which is causative of the fatal motor neuron disease amyotrophic lateral sclerosis (ALS), is demonstrated to directly bind to the U1-snRNP and SMN complexes. ALS-causative mutations in FUS/TLS are shown to