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Autor:
Kirk J. Lubick, Avram D. Walts, Mariko Ishizuka, Alexandra F. Freeman, Conrad B. Addison, Richard Green, Manfred Boehm, Kentaro Yoshii, Michael G. Katze, Sonja M. Best, Erin C. Foster, Abhilash I. Chiramel, Kristin L. McNally, Steven M. Holland, R. Travis Taylor, Seitaro Tsuruda, Mizuki Sakai, Daniel L. Kastner, Angela L. Rasmussen, Shelly J. Robertson, Brett A. Freedman, Antonella Forlino, Elena F. Boer
Publikováno v:
Cell Host & Microbe. (1):61-74
SummaryType I interferon (IFN-α/β or IFN-I) signals through two receptor subunits, IFNAR1 and IFNAR2, to orchestrate sterile and infectious immunity. Cellular pathways that regulate IFNAR1 are often targeted by viruses to suppress the antiviral eff