Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Seitaro Koshino"'
Publikováno v:
Chemistry – A European Journal. 27:15786-15794
Enantiodivergent one-pot synthesis of biaryls was developed using a catalytic amount of a single chiral source. A domino organocatalyst-mediated enantioselective Michael reaction and aldol condensation provided centrally chiral dihydronaphthalenes wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d24f22176323d78ba01428865e7bea36
https://doi.org/10.1002/chem.202102797
https://doi.org/10.1002/chem.202102797
Publikováno v:
Organic Letters. 23:6654-6658
Substituted 9-methyldecalin derivatives containing an all carbon quaternary chiral center were synthesized with excellent enantioselectivity via an organocatalyst-mediated domino reaction. The first reaction is a diphenylprolinol silyl ether-mediated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc72798aefafa4186c36b4727c9d3e96
https://doi.org/10.1021/acs.orglett.1c02196
https://doi.org/10.1021/acs.orglett.1c02196
Autor:
Naoki Haraguchi, Takeshi Yamamoto, Shusuke Hattori, Shota Hasegawa, Seitaro Koshino, Michinori Suginome, Yujiro Hayashi, Yasuhiro Uozumi
Publikováno v:
Bulletin of the Chemical Society of Japan. 94:790-797
Diphenylprolinol silyl ether is a widely used organocatalyst, and its immobilization on a solid support was investigated for the easy recycling and reuse of this catalyst. Because a silyl ether bon...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60dcaf4756ca9eb7d52ea8e16cc2d9c0
https://doi.org/10.1246/bcsj.20200355
https://doi.org/10.1246/bcsj.20200355
Publikováno v:
Chemistry, an Asian journal. 17(14)
Flow reactions using an immobilized diphenylprolinol alkyl ether catalyst 2 were investigated in three reactions of α,β-unsaturated aldehydes and nitroalkanes such as nitromethane 3, nitroethanol 10, and nitroalkane 11, bearing two carbonyl groups.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48b537ec6900d1bacdc82c22ed1aace7
https://pubmed.ncbi.nlm.nih.gov/35491236
https://pubmed.ncbi.nlm.nih.gov/35491236
Autor:
Keiichi Ishida, Eunsang Kwon, Akira Takikawa, Tohru Taniguchi, Shigenobu Umemiya, Kenji Monde, Seitaro Koshino, Yujiro Hayashi
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 26(20)
The pot-economical, highly enantioselective synthesis of axially chiral biaryls was developed by using one-pot organocatalyst-mediated domino and aromatization reactions as key steps. The axial information of the precursor, which also has central chi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c53297361af68b6b57b5a0bf368e116
https://pubmed.ncbi.nlm.nih.gov/32250025
https://pubmed.ncbi.nlm.nih.gov/32250025
Publikováno v:
Angewandte Chemie International Edition. 56:11812-11815
Enantioselective total synthesis of estradiol methyl ether has been accomplished in a pot-economical manner using five reaction vessels and four purifications. The key reaction is a diphenylprolinol silyl ether mediated domino Michael/aldol reaction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e178883965f089b5349a771b56ea42c
https://doi.org/10.1002/anie.201706046
https://doi.org/10.1002/anie.201706046
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 25(44)
A three-pot synthetic method that features the use of an organocatalyst as the key step was developed for the preparation of biaryl atropisomers. The first reaction is an asymmetric domino Michael-Henry reaction catalyzed by diphenylprolinol silyl et
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a02dfef49e90a6970a87c89d4cfaa638
https://pubmed.ncbi.nlm.nih.gov/31215688
https://pubmed.ncbi.nlm.nih.gov/31215688
Autor:
Tohru Taniguchi, Eunsang Kwon, Yujiro Hayashi, Seitaro Koshino, Akira Takikawa, Keiichi Ishida, Shigenobu Umemiya, Kenji Monde
Publikováno v:
Chemistry – A European Journal. 26:4432-4432
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96a2061a5363a70db4f6f28eaf63dfbb
https://doi.org/10.1002/chem.202000776
https://doi.org/10.1002/chem.202000776
Formal Synthesis of Ezetimibe Using a Proline-mediated, Asymmetric, Three-component Mannich Reaction
Publikováno v:
Chemistry Letters. 45:30-32
The formal total synthesis of ezetimibe was accomplished using a proline-mediated, asymmetric, three-component Mannich reaction as the key step. The two stereogenic centers on the β-lactam skeleton...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8b09a7f775cf09ae3b3bac5fcb911cd
https://doi.org/10.1246/cl.150916
https://doi.org/10.1246/cl.150916
Publikováno v:
European Journal of Organic Chemistry. 2018:5615-5615
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c334645696a01dbd34caf423b8abd3d
https://doi.org/10.1002/ejoc.201801580
https://doi.org/10.1002/ejoc.201801580