Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Seishi Nagamori"'
Publikováno v:
Biology Open, Vol 1, Iss 10, Pp 958-964 (2012)
Summary The induction mechanism of HNF-4α by spherical cell shape in human hepatoma cells, FLC-4, was investigated. To get insight into the induction mechanism of HNF-4α in three-dimensional FLC-4 cells, mRNA microarray analysis was performed. The
Externí odkaz:
https://doaj.org/article/58185639a6824c8c9a2ef3007d0c9920
Autor:
Koji Murakami, Rieko Sakukawa, Takashi Ikeda, Tomokazu Matsuura, Satoshi Hasumura, Seishi Nagamori, Yuji Yamada, Ikuo Saiki
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 1, Iss 5, Pp 424-430 (1999)
Intrahepatic metastasis is one of the malignant features of hepatocellular carcinoma (HCC). Matrix metalloproteoinases (MMPs) and urokinase-type plasminogen activator (u-PA)/plasmin, are known to be associated with the invasive properties of various
Externí odkaz:
https://doaj.org/article/736f35e9140641ed88f6193ebe5ddeaa
Autor:
Adel, Samson, Matthew J, Bentham, Karen, Scott, Gerard, Nuovo, Abigail, Bloy, Elizabeth, Appleton, Robert A, Adair, Rajiv, Dave, Adam, Peckham-Cooper, Giles, Toogood, Seishi, Nagamori, Matthew, Coffey, Richard, Vile, Kevin, Harrington, Peter, Selby, Fiona, Errington-Mais, Alan, Melcher, Stephen, Griffin
Publikováno v:
Gut
Objective Oncolytic viruses (OVs) represent promising, proinflammatory cancer treatments. Here, we explored whether OV-induced innate immune responses could simultaneously inhibit HCV while suppressing hepatocellular carcinoma (HCC). Furthermore, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::788e5c678837efa263828ddb03b9c74d
https://pubmed.ncbi.nlm.nih.gov/27902444
https://pubmed.ncbi.nlm.nih.gov/27902444
Publikováno v:
Biology Open, Vol 1, Iss 10, Pp 958-964 (2012)
Biology Open
Biology Open
Summary The induction mechanism of HNF-4α by spherical cell shape in human hepatoma cells, FLC-4, was investigated. To get insight into the induction mechanism of HNF-4α in three-dimensional FLC-4 cells, mRNA microarray analysis was performed. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0b41e1a9bd9861ca2fe544b53ab94d5
https://doi.org/10.1242/bio.20121438
https://doi.org/10.1242/bio.20121438
Autor:
Thomas Laurent, Tomokazu Matsuura, Daiki Murase, Sayaka Tsukioka, Hiroaki Oda, Seishi Nagamori
Publikováno v:
Journal of Cellular Physiology. 227:2898-2906
We characterized three-dimensional human hepatoma cell lines, functional liver cell (FLC) cell lines, to establish a highly differentiated hepatoma cell line. We investigated the effect of extracellular matrix and cell morphology on liver-specific ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59e28f0965318bb21974f34c66122425
https://doi.org/10.1002/jcp.23033
https://doi.org/10.1002/jcp.23033
Autor:
Masakiyo Sakaguchi, Yoshihiko Sakaguchi, Ichiro Akiyama, Nam Ho Huh, Masahiro Miyazaki, Seishi Nagamori
Publikováno v:
Cancer Research. 64:4155-4161
Growth inhibition by transforming growth factor (TGF)-β1 has been attributed to the induction of cyclin-dependent kinase inhibitors, among which p21/Waf1 plays a major role in many biological contexts. In the present study, two new intracellular med
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::153c1077e802b505acb1f6e7b5b2008e
https://doi.org/10.1158/0008-5472.can-03-2750
https://doi.org/10.1158/0008-5472.can-03-2750
Autor:
Yoshiharu Matsuura, Seishi Nagamori, Mami Matsuda, Tomokazu Matsuura, Masaaki Kawada, Hayato Kawakami, Hideki Aizaki, Osamu Hashimoto, Satoshi Hasumura, Hiroaki Ishiko, Tetsuro Suzuki, Tatsuo Miyamura
Publikováno v:
Virology. 314:16-25
Lack of efficient culture systems for hepatitis C virus (HCV) has been a major obstacle in HCV research. Human liver cells grown in a three-dimensional radial-flow bioreactor were successfully infected following inoculation with plasma from an HCV ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9339eca49725aff6fc51c49df43c3df3
https://doi.org/10.1016/s0042-6822(03)00383-0
https://doi.org/10.1016/s0042-6822(03)00383-0
Publikováno v:
Pathology oncology research : POR. 21(4)
Hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (CCA) are the two most common primary liver malignancies in adult patients. The molecular mechanisms underlying the pathogenesis of HCC and CCA are still poorly understood. Sonic hedg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebdcf3b00e5ce3c19d9a51aa0756990c
https://pubmed.ncbi.nlm.nih.gov/25740074
https://pubmed.ncbi.nlm.nih.gov/25740074
Autor:
Seishi Nagamori
Publikováno v:
Nihon Naika Gakkai Zasshi. 90:91-103
近年バイオ人工肝は肝不全患者に対する有力な治療法として注目されている.従来の方法との差異は患者の肝機能を患者以外の肝細胞の機能を使い回復を図る点にある.したがって利用す
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32c6d07864595d161790cd96efbaf808
https://doi.org/10.2169/naika.90.91
https://doi.org/10.2169/naika.90.91
Autor:
Masaaki Kawada, Yukihiko Oishi, Motoshi Kawahara, Tomolcazu Matsuura, Seishi Nagamori, Shoichi Onodera, Jojiro Jakada, S Hasumura, Nozomu Furuta
Publikováno v:
Medical Electron Microscopy. 31:24-30
Primary cell cultures of two human pheochromocytomas (PC) that were associated with high serum levels of adrenaline and noradrenaline were developed to study the effects of nerve growth factor (NGF) and dexamethasone on the morphology and function of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1bcd5ca8e1fda6b7279c0fc6f04ecd5
https://doi.org/10.1007/bf01547945
https://doi.org/10.1007/bf01547945