Zobrazeno 1 - 10
of 751
pro vyhledávání: '"Seipin"'
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Background Mitochondria and endoplasmic reticulum (ER) contact sites (MERCS) constitute a functional communication platform for ER and mitochondria, and they play a crucial role in the lipid homeostasis of the liver. However, it remains uncl
Externí odkaz:
https://doaj.org/article/898d5110aa4a4445b0731be0bbf3bc98
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Lipid droplets (LDs) are evolutionarily conserved dynamic organelles that play an important role in cellular physiology. Growing evidence suggests that LD biogenesis occurs at discrete endoplasmic reticulum (ER) subdomains demarcated by the lipodystr
Externí odkaz:
https://doaj.org/article/3700997952ea46c698eae669469684ab
Akademický článek
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Publikováno v:
Disease Models & Mechanisms, Vol 17, Iss 6 (2024)
Externí odkaz:
https://doaj.org/article/46e4c2b959e24f62b00fc635bdbfc57e
Autor:
Ahlima Roumane, George D. Mcilroy, Nadine Sommer, Weiping Han, Lora K. Heisler, Justin J. Rochford
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
AimsIndividuals with lipodystrophies typically suffer from metabolic disease linked to adipose tissue dysfunction including lipoatrophic diabetes. In the most severe forms of lipodystrophy, congenital generalised lipodystrophy, adipose tissue may be
Externí odkaz:
https://doaj.org/article/20b3375b0bc4440c9aaa48799bfe0502
Akademický článek
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Publikováno v:
Brain and Behavior, Vol 13, Iss 12, Pp n/a-n/a (2023)
Abstract Background Ischemic cerebrovascular disease (ICVD) is one of three fatal diseases in humans, along with heart disease and malignant tumors. Cerebral ischemia/reperfusion injury (CI/RI) is the primary cause of ICVD. Recently, seipin was repor
Externí odkaz:
https://doaj.org/article/3badb807b85249b091c29a438327f976
Publikováno v:
European Journal of Cell Biology, Vol 102, Iss 4, Pp 151362- (2023)
Lipid droplets (LD) are functionally conserved fat storage organelles found in all cell types. LDs have a unique structure comprising of a hydrophobic core of neutral lipids (fat), triacylglycerol (TAG) and cholesterol esters (CE) surrounded by a pho
Externí odkaz:
https://doaj.org/article/faebdd9aef124134a28a6568d36f6640
Autor:
Silvia Cobelo-Gómez, Sofía Sánchez-Iglesias, Alberto Rábano, Ana Senra, Pablo Aguiar, Noemí Gómez-Lado, Lara García-Varela, Iván Burgueño-García, Laura Lampón-Fernández, Antía Fernández-Pombo, Everardo Josué Díaz-López, Teresa Prado-Moraña, Beatriz San Millán, David Araújo-Vilar
Publikováno v:
Neurobiology of Disease, Vol 187, Iss , Pp 106300- (2023)
Celia's encephalopathy or progressive encephalopathy with/without lipodystrophy is a neurodegenerative disease with a fatal prognosis in childhood. It is generally caused by the c.985C > T variant in the BSCL2 gene, leading to the skipping of exon 7
Externí odkaz:
https://doaj.org/article/0cf182812fae411f97db2870888c7d1d
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Lipid droplets (LDs) serve as intracellular stores of energy-rich neutral lipids. LDs form at discrete sites in the endoplasmic reticulum (ER) and they remain closely associated with the ER during lipogenic growth and lipolytic consumption. Their hyd
Externí odkaz:
https://doaj.org/article/5a785342f1e04151aafaa18ed3c39a5d