Tissue plasminogen activator worsens experimental autoimmune encephalomyelitis by complementary actions on lymphoid and myeloid cell responses

Autor: H��lie, Pauline, Camacho-Toledano, Celia, Lesec, L��onie, Seillier, C��lia, Miralles, Antonio J, Ortega, Maria Cristina, Gu��rit, Sylvaine, Lebas, H��lo��se, Bardou, Isabelle, Vila-Del Sol, Virginia, Vivien, Denis, Le Mauff, Brigitte, Clemente, Diego, Docagne, Fabian, Toutirais, Olivier

Publikováno v: Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-17 (2021)
Hélie, Pauline; Camacho-Toledano, Celia; Lesec, Léonie; Seillier, Célia; Miralles, Antonio J; Ortega, Maria Cristina; Guérit, Sylvaine; Lebas, Héloïse; Bardou, Isabelle; Vila-Del Sol, Virginia; Vivien, Denis; Le Mauff, Brigitte; Clemente, Diego; Docagne, Fabian; Toutirais, Olivier (2021). Tissue plasminogen activator worsens experimental autoimmune encephalomyelitis by complementary actions on lymphoid and myeloid cell responses. Journal of neuroinflammation, 18(1), p. 52. BioMed Central 10.1186/s12974-021-02102-5
Journal of Neuroinflammation

Background Tissue plasminogen activator (tPA) is a serine protease involved in fibrinolysis. It is released by endothelial cells, but also expressed by neurons and glial cells in the central nervous system (CNS). Interestingly, this enzyme also contr

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https://doaj.org/article/1d3203b23fab4d6ba6cda1c955e10cd7