Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Seiko Yoshino"'
Autor:
Hiroki Kitai, Noritoshi Kato, Koichi Ogami, Shintaro Komatsu, Yu Watanabe, Seiko Yoshino, Eri Koshi, Shoma Tsubota, Yoshio Funahashi, Takahiro Maeda, Kazuhiro Furuhashi, Takuji Ishimoto, Tomoki Kosugi, Shoichi Maruyama, Kenji Kadomatsu, Hiroshi I. Suzuki
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-23 (2022)
Abstract Background Combinatorial gene regulation by multiple microRNAs (miRNAs) is widespread and closely spaced target sites often act cooperatively to achieve stronger repression (“neighborhood” miRNA cotargeting). While miRNA cotarget sites a
Externí odkaz:
https://doaj.org/article/814489ea1fa84422a7415f8368b0e8b0
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35590 (2012)
Oxygen is a vital requirement for multi-cellular organisms to generate energy and cells have developed multiple compensatory mechanisms to adapt to stressful hypoxic conditions. Such adaptive mechanisms are intricately interconnected with other signa
Externí odkaz:
https://doaj.org/article/50869f5114c04b26bd663cf5fb4875ac
Autor:
Yoshitaka Sunami, Hironori Harada, Yukari Yamazaki, Tomoko Takahara, Takashi Yokoyama, Seiko Yoshino, Takuro Nakamura
Publikováno v:
Blood Advances. 6:1827-1843
The transcriptional repressor BCL11A is involved in hematological malignancies, B-cell development, and fetal-to-adult hemoglobin switching. However, the molecular mechanism by which it promotes the development of myeloid leukemia remains largely unk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4180423fe28f79b63dd067cd281d7898
https://doi.org/10.1182/bloodadvances.2021004558
https://doi.org/10.1182/bloodadvances.2021004558
Autor:
Seiko Yoshino, Takuro Nakamura, Keiichi Ishihara, Takashi Minami, Motomi Osato, Mizuki Homme, Akiko Niibori-Nambu, Yukari Yamazaki, Tomoko Takahara, Yoshitaka Sunami, Miwa Tanaka
Publikováno v:
Leukemia. 36:558-561
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47eb300b04852aa83a0eff689b5dd9a1
https://doi.org/10.1038/s41375-021-01384-1
https://doi.org/10.1038/s41375-021-01384-1
Autor:
Seiko, Yoshino, Hiroshi I, Suzuki
Publikováno v:
Nagoya journal of medical science. 84(2)
Abnormalities in the regulation of gene expression are associated with various pathological conditions. Among the distal regulatory elements in the genome, the activation of target genes by enhancers plays a central role in the formation of cell type
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3eaaa40ae93a227257112774e100e00e
https://pubmed.ncbi.nlm.nih.gov/35967935
https://pubmed.ncbi.nlm.nih.gov/35967935
Autor:
Yurika Saitoh, Yoshinori Murakami, Yuya Fukui, Yoichi Furukawa, Yusuke Matsui, Takeharu Sakamoto, Shuichi Kaneko, Yutaka Suzuki, Masahide Seki, Teppei Shimamura, Jun-ichiro Inoue, Motoharu Seiki, Akane Kanamori, Kiyoshi Yamaguchi, Seiko Yoshino
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Cancer cells adapt to various stress conditions by optimizing gene expression profiles via transcriptional and translational regulation. However, whether and how EXOSC9, a component of the RNA exosome complex, regulates adaptation to stress condition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15afdc9b9ecb2b6700c3924c158ae8bb
http://europepmc.org/articles/PMC7283315
http://europepmc.org/articles/PMC7283315
Autor:
Yukari Yamazaki, Tomoko Takahara, Yoshitaka Sunami, Takuro Nakamura, Hiroyuki Aburatani, Aya Nakamura, Seiko Yoshino, Shuichi Tsutsumi, Takashi Yokoyama
Publikováno v:
Blood
The pseudokinase Trib1 functions as a myeloid oncogene that recruits the E3 ubiquitin ligase COP1 to C/EBPα and interacts with MEK1 to enhance extracellular signal-regulated kinase (ERK) phosphorylation. A close genetic effect of Trib1 on Hoxa9 has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bc8c2741c86edbed841b54768eb1c6a
https://pubmed.ncbi.nlm.nih.gov/33410899
https://pubmed.ncbi.nlm.nih.gov/33410899
Autor:
Seiko Yoshino, Suzuki, Hiroshi I.
Publikováno v:
Nagoya Journal of Medical Science; May2022, Vol. 84 Issue 2, p216-229, 14p
Autor:
Takeharu Sakamoto, Toshiro Hara, Hiroki J. Nakaoka, Motoharu Seiki, Akane Kanamori, Seiko Yoshino, Yoshinori Murakami
Publikováno v:
Cell Discovery
Loss of anchorage to the extracellular matrix leads to apoptosis (anoikis) in normal cells, but cancerous cells are usually resistant to such stress. Here we report the pivotal role of an E3 ubiquitin ligase, ring-finger protein 126 (RNF126), in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76db8d1c285d71042979b4a0ee3823a2
https://doi.org/10.1038/celldisc.2016.19
https://doi.org/10.1038/celldisc.2016.19
Autor:
Seiko Yoshino, Yusuke Matsui, Takeharu Sakamoto, Toshiro Hara, Teppei Shimamura, Hiroki J. Nakaoka, Akane Kanamori, Motoharu Seiki, Yoshinori Murakami, Hiroshi Sato
Publikováno v:
Scientific Reports
Unlike most cells, cancer cells activate hypoxia inducible factor-1 (HIF-1) to use glycolysis even at normal oxygen levels, or normoxia. Therefore, HIF-1 is an attractive target in cancer therapy. However, the regulation of HIF-1 during normoxia is n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32b703b6795cd9cb7400c0a3a135aba2