Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Seiko Kozai"'
Autor:
Kana Ikemoto, Shinya Kobayashi, Yu Haranosono, Seiko Kozai, Tomoyuki Wada, Hideki Tokushige, Akio Kawamura
Publikováno v:
BMC Ophthalmology, Vol 20, Iss 1, Pp 1-7 (2020)
Abstract Background We aimed to demonstrate the contribution of anti-inflammatory and anti-virulence effects of azithromycin (AZM) in ocular surface infection treatment. Methods Staphylococcus aureus was injected into the corneal stroma of rabbits to
Externí odkaz:
https://doaj.org/article/469fc99989dc41e49dd85087d91f3765
Publikováno v:
Ophthalmology and Therapy, Vol 9, Iss 1, Pp 115-125 (2020)
Abstract Introduction This study was aimed to compare ocular tissue distribution and systemic exposure of brimonidine and timolol after single topical administration to rabbits of fixed-combination ophthalmic solution of 0.1% brimonidine tartrate and
Externí odkaz:
https://doaj.org/article/ca8e17d2d2814c93accf14397434a086
Autor:
Keisuke Shinno, Kazuya Kurokawa, Seiko Kozai, Akio Kawamura, Katsuhiro Inada, Hideki Tokushige
Publikováno v:
Ophthalmology and Therapy, Vol 8, Iss 2, Pp 271-277 (2019)
Abstract Introduction Brimonidine bioavailability in the aqueous humor depends on the solution pH following topical administration. The purpose of this study was to investigate the effect of solution pH on brimonidine distribution in the posterior oc
Externí odkaz:
https://doaj.org/article/c6b457efd37a4c29bbd47ccb74744aff
Autor:
Tetsuo Kida, Seiko Kozai, Hiroaki Takahashi, Mitsuyoshi Isaka, Hideki Tokushige, Taiji Sakamoto
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96481 (2014)
PURPOSE: To evaluate the pharmacokinetics and efficacy of topically applied nonsteroidal anti-inflammatory drugs (NSAIDs) in the retinochoroidal tissues of rabbits. METHODS: The cyclooxygenase (COX) inhibitory activity of diclofenac, bromfenac, and a
Externí odkaz:
https://doaj.org/article/4d0552958cae4aa5921eed4e03e711fd
Publikováno v:
Ophthalmology and Therapy, Vol 9, Iss 1, Pp 115-125 (2020)
Ophthalmology and Therapy
Ophthalmology and Therapy
Introduction This study was aimed to compare ocular tissue distribution and systemic exposure of brimonidine and timolol after single topical administration to rabbits of fixed-combination ophthalmic solution of 0.1% brimonidine tartrate and 0.5% tim
Autor:
Hideki Tokushige, Akio Kawamura, Katsuhiro Inada, Kazuya Kurokawa, Keisuke Shinno, Seiko Kozai
Publikováno v:
Ophthalmology and Therapy
Ophthalmology and Therapy, Vol 8, Iss 2, Pp 271-277 (2019)
Ophthalmology and Therapy, Vol 8, Iss 2, Pp 271-277 (2019)
Introduction Brimonidine bioavailability in the aqueous humor depends on the solution pH following topical administration. The purpose of this study was to investigate the effect of solution pH on brimonidine distribution in the posterior ocular tiss
Autor:
Wakasa Shigemi, Keisuke Shinno, Masaaki Kurata, Seiko Kozai, Eriko Kunikane, Gen Suzuki, Akio Kawamura
Publikováno v:
Current eye research. 46(3)
The aim of this study was to compare the ocular and systemic absorption of brimonidine (BMD) and brinzolamide (BZM) in rabbits after the topical administration of a fixed-combination ophthalmic suspension of 0.1% BMD tartrate and 1% BZM (FCBB) with t
Autor:
Tomoyuki Wada, Seiko Kozai, Yu Haranosono, Akio Kawamura, Shinya Kobayashi, Hideki Tokushige, Ikemoto Kana
Publikováno v:
BMC Ophthalmology
BMC Ophthalmology, Vol 20, Iss 1, Pp 1-7 (2020)
BMC Ophthalmology, Vol 20, Iss 1, Pp 1-7 (2020)
Background We aimed to demonstrate the contribution of anti-inflammatory and anti-virulence effects of azithromycin (AZM) in ocular surface infection treatment. Methods Staphylococcus aureus was injected into the corneal stroma of rabbits to induce k
Publikováno v:
International Journal of Antimicrobial Agents. 49:113-115
Autor:
Thomas R. Shearer, Chiho Yabuta, Seiko Kozai, Mitsuyoshi Azuma, Yayoi Kishimoto, Ayumi Mori, Akira Ohtori
Publikováno v:
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics. 33(7)
To establish the in silico ocular pharmacokinetic modeling for eye drops, and to simulate the dose regimen for FK962 in human choroid/retinal diseases.Pharmacokinetics for FK962 in vivo was performed by a single instillation of drops containing 0.1%T