MT5-MMP is a new pro-amyloidogenic proteinase that promotes amyloid ă pathology and cognitive decline in a transgenic mouse model of Alzheimer's disease

Autor: Baranger, Kévin, Marchalant, Yannick, Bonnet, Amandine E., Crouzin, Nadine, Carrete, Alex, Paumier, Jean-Michel, Py, Nathalie A., Bernard, Anne, Bauer, Charlotte, Charrat, Eliane, Moschke, Katrin, Seiki, Mothoharu, Vignes, Michel, Lichtenthaler, Stefan F., Checler, Frédéric, Khrestchatisky, Michel, Rivera, Santiago

Publikováno v: Cellular and Molecular Life Sciences
Cellular and Molecular Life Sciences, 2016, 73 (1), pp.217-236. ⟨10.1007/s00018-015-1992-1⟩
Cellular and Molecular Life Sciences, Springer Verlag, 2016, 73 (1), pp.217-236. ⟨10.1007/s00018-015-1992-1⟩

International audience; Membrane-type 5-matrix metalloproteinase (MT5-MMP) is a proteinase mainly expressed in the nervous system with emerging roles in brain pathophysiology. The implication of MT5-MMP in Alzheimer’s disease (AD), notably its inte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::5070566a7e148dfa2b0312d0e21d3ef4
https://hal.science/hal-01477822