Lipid nanoparticle-encapsulated DOCK11-siRNA efficiently reduces hepatitis B virus cccDNA level in infected mice.

Autor: Okada H; Information-Based Medicine Development, Graduate School of Medical Sciences, Kanazawa University, Ishikawa, Japan., Sakamoto T; Department of Cancer Biology, Institute of Biomedical Science, Kansai Medical University, Osaka, Japan., Nio K; Department of Gastroenterology, Kanazawa University Graduate School of Medical Science, Ishikawa, Japan., Li Y; Department of Gastroenterology, Kanazawa University Graduate School of Medical Science, Ishikawa, Japan., Kuroki K; Department of Gastroenterology, Kanazawa University Graduate School of Medical Science, Ishikawa, Japan., Sugimoto S; Department of Gastroenterology, Kanazawa University Graduate School of Medical Science, Ishikawa, Japan., Shimakami T; Department of Gastroenterology, Kanazawa University Graduate School of Medical Science, Ishikawa, Japan., Doi N; Department of Biosciences and Informatics, Faculty of Science and Technology, Keio University, Kanagawa, Japan., Honda M; Department of Gastroenterology, Kanazawa University Graduate School of Medical Science, Ishikawa, Japan., Seiki M; Department of Gastroenterology, Kanazawa University Graduate School of Medical Science, Ishikawa, Japan., Kaneko S; Information-Based Medicine Development, Graduate School of Medical Sciences, Kanazawa University, Ishikawa, Japan., Yamashita T; Department of Gastroenterology, Kanazawa University Graduate School of Medical Science, Ishikawa, Japan.

Publikováno v: Molecular therapy. Methods & clinical development [Mol Ther Methods Clin Dev] 2024 Jun 24; Vol. 32 (3), pp. 101289. Date of Electronic Publication: 2024 Jun 24 (Print Publication: 2024).

Functional analysis of RRAS2 pathogenic variants with a Noonan-like phenotype.

Autor: Iida T; Department of Genome Medicine, National Center for Child Health and Development, Tokyo, Japan., Igarashi A; Department of Genome Medicine, National Center for Child Health and Development, Tokyo, Japan., Fukunaga K; Department of Genome Medicine, National Center for Child Health and Development, Tokyo, Japan.; Department of Systems Biochemistry in Pathology and Regeneration, Yamaguchi University Graduate School of Medicine, Yamaguchi, Japan., Aoki T; Department of Genome Medicine, National Center for Child Health and Development, Tokyo, Japan., Hidai T; Department of Genome Medicine, National Center for Child Health and Development, Tokyo, Japan., Yanagi K; Department of Genome Medicine, National Center for Child Health and Development, Tokyo, Japan., Yamamori M; Department of Genome Medicine, National Center for Child Health and Development, Tokyo, Japan., Satou K; Department of Genome Medicine, National Center for Child Health and Development, Tokyo, Japan., Go H; Department of Pediatrics, Fukushima Medical University School of Medicine, Fukushima, Japan., Kosho T; Department of Medical Genetics, Shinshu University School of Medicine, Matsumoto, Japan., Maki R; School of Life Science and Technology, Tokyo Institute of Technology, Yokohama, Japan., Suzuki T; School of Life Science and Technology, Tokyo Institute of Technology, Yokohama, Japan., Nitta Y; Brain Research Institute, Niigata University, Niigata, Japan., Sugie A; Brain Research Institute, Niigata University, Niigata, Japan., Asaoka Y; Department of Systems Biochemistry in Pathology and Regeneration, Yamaguchi University Graduate School of Medicine, Yamaguchi, Japan., Furutani-Seiki M; Department of Systems Biochemistry in Pathology and Regeneration, Yamaguchi University Graduate School of Medicine, Yamaguchi, Japan., Kimura T; Division of Human Genetics, Department of Integrated Genetics, National Institute of Genetics, Mishima, Japan.; Medical Genome Center, Research Institute, National Center for Geriatrics and Gerontology, Obu, Japan., Matsubara Y; National Center for Child Health and Development, Tokyo, Japan., Kaname T; Department of Genome Medicine, National Center for Child Health and Development, Tokyo, Japan.

Publikováno v: Frontiers in genetics [Front Genet] 2024 Mar 27; Vol. 15, pp. 1383176. Date of Electronic Publication: 2024 Mar 27 (Print Publication: 2024).

EphA2 Proteolytic Fragment as a Sensitive Diagnostic Biomarker for Very Early-stage Pancreatic Ductal Carcinoma.

Autor: Sato S; Molecular Pathology and Genetics Division, Kanagawa Cancer Center Research Institute, Yokohama, Japan.; Department of Pathology, Kanagawa Cancer Center Hospital, Yokohama, Japan.; Morphological Analysis Laboratory, Kanagawa Cancer Center Research Institute, Yokohama, Japan., Nakagawa M; Research and Development, Abbott Japan LLC, Chiba, Japan.; Department of Life Science and Technology, Tokyo Institute of Technology, Yokohama, Japan., Terashima T; Advanced Preventive Medical Sciences Research Center, Kanazawa University Hospital, Kanazawa, Japan., Morinaga S; Department of Gastroenterological Surgery, Kanagawa Cancer Center Hospital, Yokohama, Japan., Miyagi Y; Molecular Pathology and Genetics Division, Kanagawa Cancer Center Research Institute, Yokohama, Japan.; Department of Pathology, Kanagawa Cancer Center Hospital, Yokohama, Japan., Yoshida E; Morphological Analysis Laboratory, Kanagawa Cancer Center Research Institute, Yokohama, Japan., Yoshimura T; Morphological Analysis Laboratory, Kanagawa Cancer Center Research Institute, Yokohama, Japan., Seiki M; Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan., Kaneko S; Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan., Ueno M; Department of Gastroenterology, Kanagawa Cancer Center Hospital, Yokohama, Japan., Yamashita T; Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan., Koshikawa N; Department of Life Science and Technology, Tokyo Institute of Technology, Yokohama, Japan.; Clinical Cancer Proteomics Laboratory, Kanagawa Cancer Center Research Institute, Yokohama, Japan.

Publikováno v: Cancer research communications [Cancer Res Commun] 2023 Sep 15; Vol. 3 (9), pp. 1862-1874.

Monoclonal Integration of Human T-Cell Leukemia Provirus in All Primary Tumors of Adult T-Cell Leukemia Suggests Causative Role of Human T-Cell Leukemia Virus in the Disease

Autor: Yoshida, M., Seiki, M., Yamaguchi, K., Takatsuki, K.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 1984 Apr . 81(8), 2534-2537.

Externí odkaz: https://www.jstor.org/stable/23587

Mint3 depletion-mediated glycolytic and oxidative alterations promote pyroptosis and prevent the spread of Listeria monocytogenes infection in macrophages.

Autor: Uematsu T; Biomedical Laboratory, Division of Biomedical Research, Kitasato University Medical Center, Arai, Kitamoto, Saitama, Japan. tuematsu@insti.kitasato-u.ac.jp., Tsuchiya K; Division of Immunology and Molecular Biology, Cancer Research Institute, Kanazawa University, Kakuma-machi, Kanazawa, Ishikawa, Japan., Kobayashi N; Biomedical Laboratory, Division of Biomedical Research, Kitasato University Medical Center, Arai, Kitamoto, Saitama, Japan., Seiki M; Division of Cancer Cell Research, Institute of Medical Science, The University of Tokyo, Shirokanedai, Minato-ku, Tokyo, Japan., Inoue JI; Division of Cellular and Molecular Biology, Institute of Medical Science, The University of Tokyo, Shirokanedai, Minato-ku, Tokyo, Japan., Kaneko S; Department of System Biology, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Takara-machi, Takara-machi, Kanazawa, Ishikawa, Japan., Sakamoto T; Division of Cellular and Molecular Biology, Institute of Medical Science, The University of Tokyo, Shirokanedai, Minato-ku, Tokyo, Japan. t-saka@staff.kanazawa-u.ac.jp.; Department of System Biology, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Takara-machi, Takara-machi, Kanazawa, Ishikawa, Japan. t-saka@staff.kanazawa-u.ac.jp.

Publikováno v: Cell death & disease [Cell Death Dis] 2021 Apr 14; Vol. 12 (4), pp. 404. Date of Electronic Publication: 2021 Apr 14.