Zobrazeno 1 - 10
of 157
pro vyhledávání: '"Seijiro Hosokawa"'
Autor:
Tomoyuki Oshio, Rei Kawashima, Yuki I Kawamura, Teruki Hagiwara, Noriko Mizutani, Toshihiko Okada, Takeshi Otsubo, Kyoko Inagaki-Ohara, Akihiro Matsukawa, Tatsuya Haga, Shigeru Kakuta, Yoichiro Iwakura, Seijiro Hosokawa, Taeko Dohi
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94445 (2014)
Chemokine (C-C motif) receptor 8 (CCR8), the chemokine receptor for chemokine (C-C motif) ligand 1 (CCL1), is expressed in T-helper type-2 lymphocytes and peritoneal macrophages (PMφ) and is involved in various pathological conditions, including per
Externí odkaz:
https://doaj.org/article/66da9cc3a05a4116bd139b7990b85f75
Autor:
Hitoshi Fumiyama, Arata Takahashi, Yuma Suzuki, Naoto Fujioka, Hirotake Matsumoto, Seijiro Hosokawa
Publikováno v:
The Journal of organic chemistry. 87(22)
The total synthesis of alcyonolide, an antitumor xenicn diterpenoid, has been achieved. The inverse electron demand hetero-Diels-Alder reaction using a dienophile possessing an electron-withdrawing group provided the endo adduct which included a cond
Publikováno v:
Organicbiomolecular chemistry. 20(42)
We disclose the first synthesis of the marine natural product, (+)-boneratamide A, whose structure is composed of a terpene unit linkedivia/ian amide bond to a pyroglutamic acid moiety. The key step in this route is a bioinspired Ugi reaction of (+)-
Publikováno v:
The Journal of Organic Chemistry. 86:7787-7796
The [3 + 2]-cycloaddition reaction between N-tosylaziridines and α,β-unsaturated ketones was promoted with lithium iodide. The reaction proceeded under mild conditions to provide N-tosylpyrrolidines. Quaternary carbon-possessing 3,3-disubstituted p
Autor:
Seijiro Hosokawa
Publikováno v:
Journal of Synthetic Organic Chemistry, Japan. 79:109-119
Autor:
Yoshiyasu Ichikawa, Takahiro Kinutani, Yoshimine Sakogawa, Keisuke Nakanishi, Rika Ochi, Seijiro Hosokawa, Toshiya Masuda
Publikováno v:
HETEROCYCLES. 106:649
Autor:
Seijiro Hosokawa, Yutaro Udagawa, Toshiki Yamasaki, Yoshiyasu Ichikawa, Toshiya Masuda, Keisuke Nakanishi
Publikováno v:
Synthesis. 51:2305-2310
A pathway is proposed for the biosynthesis of the unique homodimeric terpene, halichonadin H. The proposed biosynthetic pathway involves two key Passerini reactions of eudesmane-type terpene isocyanides. The Passerini reaction of a model terpene isoc
Autor:
Haruka Sato, Seijiro Hosokawa
Publikováno v:
Synlett. 30:577-580
The C1–C17 segment of bafilomycin N has been synthesized. The C1–C11 segment was synthesized by the anti-selective vinylogous Mukaiyama aldol reaction with a chiral vinylketene silyl N,O-acetal and the Horner–Wadsworth–Emmons reaction, wherea
Autor:
Seijiro Hosokawa, Aakash Sengupta
Publikováno v:
Synlett. 30:709-712
A total synthesis of PF1163B has been achieved. The vinylogous Mukaiyama aldol reaction of ketene silyl N,O-acetal 6 (ent-6) mediated by excess TiCl4 proceeded with saturated aldehydes to give adduct 10 in moderate yield with moderate stereoselectivi
Autor:
Seijiro Hosokawa, Aakash Sengupta
Publikováno v:
Tetrahedron Letters. 60:411-414
2-Isopropylbenzimidazole and 2-methylbenzimidazole have been found to be effective bulky proton sources for stereoselective protonation of chiral enolate anions. 2-Isopropylbenzimidazole worked in the stereoselective protonation of the Birch reductio