Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Seiji Yoshimura"'
Publikováno v:
Veterinary Surgery. 51:330-334
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c9c475f87a663248d7bc45e92035f5c
https://doi.org/10.1111/vsu.13749
https://doi.org/10.1111/vsu.13749
Autor:
Roman V. Koziy, Jose L. Bracamonte, Seiji Yoshimura, Paulos Chumala, Elemir Simko, George S. Katselis
Publikováno v:
Journal of proteomics. 261
Septic arthritis (SA) is a life-threatening condition in horses, and identifying eradication of infection in equine SA is challenging. This study explored the discovery of putative biomarkers for the eradication of joint infection in horses. We perfo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78007f466f21ae8b1a894e685d93a765
https://pubmed.ncbi.nlm.nih.gov/35346876
https://pubmed.ncbi.nlm.nih.gov/35346876
Autor:
David A. Barrett, Seiji Yoshimura, Masae Sawada, Toshio Yamanaka, Takuya Makino, Eisaku Tsujii, Masahiro Neya
Publikováno v:
Bioorganicmedicinal chemistry letters. 30(16)
Evidence indicates that hepatitis C virus (HCV) utilizes cellular cyclophilin proteins in its replication, and cyclophilin inhibitors represent a new class of anti-HCV agents. We have established an efficient synthetic methodology to generate FR90145
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a95260f806bd252899e519cbbb53af2
https://pubmed.ncbi.nlm.nih.gov/32631528
https://pubmed.ncbi.nlm.nih.gov/32631528
Publikováno v:
Bioorganicmedicinal chemistry letters. 30(14)
HCV utilizes cellular protein cyclophilins in the virus replication cycle and cyclophilin inhibitors have become a new class of anti-HCV agents. In our screening of natural products, we identified a unique cyclosporin analogue, FR901459, as a cycloph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e2285b90b9ecdbc79c5bf372ee08947
https://pubmed.ncbi.nlm.nih.gov/32527551
https://pubmed.ncbi.nlm.nih.gov/32527551
Autor:
Masahiko Ozaki, Yuki Nakagawa, Ikuya Oshima, Shunsuke Muramatsu, Yoshihito Ohta, Koichi Shinoto, Yukio Kakuta, Seiji Yoshimura, Yasushi Okazaki, Daisuke Horibe
Publikováno v:
The Japanese Journal of Gastroenterological Surgery. 51:154-161
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a3bccc25e9702d1a57eeb2dca3e8549
https://doi.org/10.5833/jjgs.2017.0028
https://doi.org/10.5833/jjgs.2017.0028
Autor:
Masahiko Ozaki, Yasushi Okazaki, Ikuya Oshima, Hiroki Matsuki, Seiji Yoshimura, Koichi Shinoto
Publikováno v:
Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association). 78:383-387
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b30bcae53376adf57503f7400807d1ca
https://doi.org/10.3919/jjsa.78.383
https://doi.org/10.3919/jjsa.78.383
Autor:
Daisuke Sasuga, Hirofumi Ishii, Ayako Moritomo, Kazuo Kurosawa, Ryota Shiraki, Tomoaki Kawano, Mitsuru Hosaka, Seiji Yoshimura, Takanori Koike, Hiroki Fukudome, Shinya Mimasu
Publikováno v:
Chemicalpharmaceutical bulletin. 67(8)
We synthesized and evaluated novel 5-[2-(thiophen-2-yl)propan-2-yl]-4H-1,2,4-triazole derivatives as 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitors. Optimization of the thiophene ring and the substituents on the 1,2,4-triazole ring p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e873e3ce1a9d632552b40556811975b
https://pubmed.ncbi.nlm.nih.gov/31366832
https://pubmed.ncbi.nlm.nih.gov/31366832
Autor:
Seiji, Yoshimura, Roman V, Koziy, Ryan, Dickinson, Igor, Moshynskyy, Joscelyn A, McKenzie, Elemir, Simko, José L, Bracamonte
Publikováno v:
Can J Vet Res
While serum amyloid A (SAA) has been investigated as a potential marker for septic arthritis in horses, no study has reported on whether SAA can be used to detect eradication of joint infection. Therefore, the objective of this study was to investiga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::da2a2c83dd4a7c17af8d0d2b4cee4799
https://pubmed.ncbi.nlm.nih.gov/32801454
https://pubmed.ncbi.nlm.nih.gov/32801454
Autor:
Roman V, Koziy, Seiji, Yoshimura, Ryan, Dickinson, Joanna M, Rybicka, Igor, Moshynskyy, Musangu, Ngeleka, Jose L, Bracamonte, Elemir, Simko
Publikováno v:
Canadian journal of veterinary research = Revue canadienne de recherche veterinaire. 83(1)
Septic arthritis is an important disease in horses, necessitating aggressive and prolonged therapy. In order to guide therapy, reliable methods of detecting the eradication of infection are needed. Therefore, the objective of this study was to invest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0ed0aca7d5d9f3aaaebefac8fe0a2c11
https://pubmed.ncbi.nlm.nih.gov/30670899
https://pubmed.ncbi.nlm.nih.gov/30670899
Autor:
Takashi Ogiyama, Koichi Yonezawa, Seiji Yoshimura, Shuichiro Kakimoto, Makoto Inoue, Jun-Ichi Shishikura, Takayasu Gotoh, Toshihiro Watanabe, Akiko Koakutsu, Tetsuo Kiso, Naoko Katayama
Publikováno v:
Bioorganic & Medicinal Chemistry. 23:4638-4648
In lead optimization efforts starting from the tetrahydroisoquinoline (S)-1, we identified 2-{[(2R)-2-hydroxypropyl]amino}-1-[(1S)-8-methoxy-1-phenyl-3,4-dihydroisoquinolin-2(1H)-yl]ethanone ((1S)-8t) as a novel orally active small-molecule N-type ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abfdde053acc2da97352d3733c1a4112
https://doi.org/10.1016/j.bmc.2015.05.053
https://doi.org/10.1016/j.bmc.2015.05.053