Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Seiji Shiraishi"'
Publikováno v:
Biology, Vol 13, Iss 2, p 91 (2024)
Non-obese metabolic dysfunction-associated steatotic liver disease (MASLD) has been associated with cardiovascular-related mortality, leading to a higher mortality rate compared to the general population. However, few reports have examined cardiovasc
Externí odkaz:
https://doaj.org/article/975de1278dbe4524820cd533b72b599c
Autor:
Kanako Miyano, Katsuya Ohbuchi, Yuka Sudo, Kouichiro Minami, Toru Yokoyama, Masahiro Yamamoto, Miaki Uzu, Miki Nonaka, Seiji Shiraishi, Hiroaki Murata, Yoshikazu Higami, Yasuhito Uezono
Publikováno v:
Journal of Pharmacological Sciences, Vol 143, Iss 4, Pp 320-324 (2020)
Cellular dielectric spectroscopy (CDS) is a novel technology enabling pharmacological evaluation of multiple receptor types with a label-free cell-based assay. We evaluated activities of a family of ligand-gated channels, transient receptor potential
Externí odkaz:
https://doaj.org/article/c353329a3d5446a2926a09e994c6518d
Autor:
Yuko Tanabe, Seiji Shiraishi, Kenji Hashimoto, Kazutaka Ikeda, Daisuke Nishizawa, Junko Hasegawa, Akihiko Shimomura, Yukinori Ozaki, Nobuko Tamura, Mayu Yunokawa, Kan Yonemori, Toshimi Takano, Hidetaka Kawabata, Kenji Tamura, Yasuhiro Fujiwara, Chikako Shimizu
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-7 (2020)
Abstract Background Sodium channels located in the dorsal root ganglion, particularly Nav1.7 and Nav1.8, encoded by SCN9A and SCN10A, respectively, act as molecular gatekeepers for pain detection. Our aim was to determine the association between TIPN
Externí odkaz:
https://doaj.org/article/f0550d61d10845b988866f542ddcb3ca
Autor:
Kanako Miyano, Minori Ikehata, Kaori Ohshima, Yuki Yoshida, Yasuhiro Nose, Sei-ichi Yoshihara, Katsuyuki Oki, Seiji Shiraishi, Miaki Uzu, Miki Nonaka, Yoshikazu Higami, Yasuhito Uezono
Publikováno v:
PLoS ONE, Vol 17, Iss 2 (2022)
Mesenchymal stem cells (MSCs), which are isolated from adipose tissue (AD-MSCs), umbilical cord (UC-MSCs), or bone marrow, have therapeutic potential including anti-inflammatory and immunomodulatory activities. It was recently reported that MSCs are
Externí odkaz:
https://doaj.org/article/d3c62824590b4058be9be33347c89cb9
Autor:
Thomas P. Chapman, Daniele Corridoni, Seiji Shiraishi, Sumeet Pandey, Anna Aulicino, Simon Wigfield, Maria do Carmo Costa, Marie-Laëtitia Thézénas, Henry Paulson, Roman Fischer, Benedikt M. Kessler, Alison Simmons
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
The interplay between NOD2 and TLR2 following recognition of components of the bacterial cell wall peptidoglycan is well-established, however their role in redirecting metabolic pathways in myeloid cells to degrade pathogens and mount antigen present
Externí odkaz:
https://doaj.org/article/ec8c671e88244eb8bddf0895cc76210a
Autor:
Daniele Corridoni, Seiji Shiraishi, Thomas Chapman, Tessa Steevels, Daniele Muraro, Marie-Laëtitia Thézénas, Gennaro Prota, Ji-Li Chen, Uzi Gileadi, Nicola Ternette, Vincenzo Cerundolo, Alison Simmons
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
NOD2 and TLR2 recognize components of bacterial cell wall peptidoglycan and direct defense against enteric pathogens. CD8+ T cells are important for immunity to such pathogens but how NOD2 and TLR2 induce antigen specific CD8+ T cell responses is unk
Externí odkaz:
https://doaj.org/article/9eb738e749514517b1f3c064aa982497
Autor:
Satoshi Murakami, Yuka Sudo, Kanako Miyano, Hitomi Nishimura, Motohiro Matoba, Seiji Shiraishi, Hiroki Konno, Yasuhito Uezono
Publikováno v:
Journal of Pharmacological Sciences, Vol 130, Iss 2, Pp 72-77 (2016)
Non-selective transient receptor potential vanilloid (TRPV) cation channels are activated by various insults, including exposure to heat, acidity, and the compound capsaicin, resulting in sensations of pain in the skin, visceral organs, and oral cavi
Externí odkaz:
https://doaj.org/article/e5a4f7c66c794a1aba836849d7812ca7
Autor:
Kiyoshi Terawaki, Yohei Kashiwase, Yumi Sawada, Hirofumi Hashimoto, Mitsuhiro Yoshimura, Katsuya Ohbuchi, Yuka Sudo, Masami Suzuki, Kanako Miyano, Seiji Shiraishi, Yoshikazu Higami, Kazuyoshi Yanagihara, Tomohisa Hattori, Yoshio Kase, Yoichi Ueta, Yasuhito Uezono
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173113 (2017)
Cancer cachexia (CC) is a multifactorial disease characterized by decreased food intake and loss of body weight due to reduced musculature with or without loss of fat mass. Patients with gastric cancer have a high incidence of cachexia. We previously
Externí odkaz:
https://doaj.org/article/c2eadc0372d54a64bf52e5bc854962ca
Publikováno v:
Journal of Pharmacological Sciences, Vol 112, Iss 4, Pp 424-431 (2010)
G protein–coupled receptors, in particular, Ca2+-mobilizing Gq-coupled receptors have been reported to be targets for anesthetics. Opioids are commonly used analgesics in clinical practice, but the effects of anesthetics on the opioid μ-receptors
Externí odkaz:
https://doaj.org/article/8a391bfff7d74c74a6f0607c5d5523aa
Autor:
Katsuya Morita, Seiji Shiraishi, Naoyo Motoyama, Tomoya Kitayama, Takashi Kanematsu, Yasuhito Uezono, Toshihiro Dohi
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e91746 (2014)
Bone cancer pain is the most severe among cancer pain and is often resistant to current analgesics. Thus, the development of novel analgesics effective at treating bone cancer pain are desired. Platelet-activating factor (PAF) receptor antagonists we
Externí odkaz:
https://doaj.org/article/fc5716b84f98406c8afa26062897669e