Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Seiji Naganuma"'
Autor:
Keisuke Taniuchi, Makoto Ueno, Tomoyuki Yokose, Masahiko Sakaguchi, Reiko Yoshioka, Mitsunari Ogasawara, Takuhiro Kosaki, Seiji Naganuma, Mutsuo Furihata
Publikováno v:
PLoS ONE, Vol 17, Iss 3 (2022)
The upregulation of PODXL and ITGB1 in surgically resected pancreatic cancer tissues is correlated with an unfavorable postoperative prognosis. The aim of this study was to investigate whether PODXL and ITGB1 are useful preoperative markers for the p
Externí odkaz:
https://doaj.org/article/92275749370547289d3d945824a6b159
Autor:
Takashi Kijima, Hiroshi Nakagawa, Masataka Shimonosono, Prasanna M. Chandramouleeswaran, Takeo Hara, Varun Sahu, Yuta Kasagi, Osamu Kikuchi, Koji Tanaka, Veronique Giroux, Amanda B. Muir, Kelly A. Whelan, Shinya Ohashi, Seiji Naganuma, Andres J. Klein-Szanto, Yoshiaki Shinden, Ken Sasaki, Itaru Omoto, Yoshiaki Kita, Manabu Muto, Adam J. Bass, J. Alan Diehl, Gregory G. Ginsberg, Yuichiro Doki, Masaki Mori, Yasuto Uchikado, Takaaki Arigami, Narayan G. Avadhani, Devraj Basu, Anil K. Rustgi, Shoji Natsugoe
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 1, Pp 73-91 (2019)
Background & Aims: Oropharyngeal and esophageal squamous cell carcinomas, especially the latter, are a lethal disease, featuring intratumoral cancer cell heterogeneity and therapy resistance. To facilitate cancer therapy in personalized medicine, thr
Externí odkaz:
https://doaj.org/article/7488edc6ab024bcda04958703e1f2938
Publikováno v:
Cancer Medicine, Vol 7, Iss 11, Pp 5733-5751 (2018)
Abstract WAVE2 is a member of the WASP/WAVE family of actin cytoskeletal regulatory proteins; unfortunately, little is known about its function in pancreatic cancers. In this study, we report the role of WAVE2 in the motility and invasiveness of panc
Externí odkaz:
https://doaj.org/article/af80c4bba28345dfbbd3e58da09a1c73
Autor:
Mitsuteru Natsuizaka, Kelly A. Whelan, Shingo Kagawa, Koji Tanaka, Veronique Giroux, Prasanna M. Chandramouleeswaran, Apple Long, Varun Sahu, Douglas S. Darling, Jianwen Que, Yizeng Yang, Jonathan P. Katz, E. Paul Wileyto, Devraj Basu, Yoshiaki Kita, Shoji Natsugoe, Seiji Naganuma, Andres J. Klein-Szanto, J. Alan Diehl, Adam J. Bass, Kwok-Kin Wong, Anil K. Rustgi, Hiroshi Nakagawa
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
Notch receptors can exert different roles in cancer. In this manuscript, the authors reveal that Notch1 activation and EMT promote tumor initiation and cancer cell heterogeneity in squamous cell carcinoma, while the repression of Notch3 by ZEB1 limit
Externí odkaz:
https://doaj.org/article/6f8691ad6d324ab0a967f60181be89c5
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0217920 (2019)
We previously reported that overexpression of PODXL, BCL7B, and ARHGEF4 in pancreatic cancer tissue is correlated with pancreatic cancer-related survival. The aim of this study was to investigate the use of PODXL, BCL7B, ARHGEF4, and the integrin fam
Externí odkaz:
https://doaj.org/article/afa1b55735db41c79c3752a8ed710d1c
Autor:
Hiroshi Nakagawa, Meenhard Herlyn, J. Alan Diehl, Andres J. Klein-Szanto, Phyllis A. Gimotty, Devraj Basu, Douglas S. Darling, Momo Nakagawa, Ross A. Kalman, Hiroshi Itoh, Sotai Kimura, Shingo Kagawa, Seiji Naganuma, Mitsuteru Natsuizaka, Shinya Ohashi
PDF file - 347K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83ac618df784415ef6c0f495840431a3
https://doi.org/10.1158/0008-5472.22389635.v1
https://doi.org/10.1158/0008-5472.22389635.v1
Autor:
Masaya Sugiyama, Hideaki Kinugasa, Naoya Sakamoto, Kenichi Morikawa, Takuya Sho, Koji Ogawa, Hiroshi Takeda, Masashi Mizokami, Shunsuke Ohnishi, Seiji Naganuma, Shinya Ohashi, Mitsuteru Natsuizaka, Osamu Maehara, Megumi Kimura, Naoto Okubo, Goki Suda, Gouki Kanbe, Taku Shigesawa, Shingo Kagawa, Masato Nakai
Publikováno v:
Cancer Biol Ther
Fibroblast growth factors (FGFs) and their receptors (FGFRs) are important for signaling to maintain cancer stem-like cells (CSCs) in esophageal squamous cell carcinoma (ESCC). However, which FGF receptor, 1, 2, 3, 4, and L1, is essential or whether
Autor:
Waka Iwashita, Kaoru Furihata, Akiko Yano, Makoto Toi, Seiji Naganuma, Atsushi Kurabayashi, Chiharu Tanaka, Mutsuo Furihata
Publikováno v:
Journal of Cutaneous Pathology. 48:451-454
Acantholytic dyskeratotic acanthoma is a rare variant of epidermal acanthoma. It has a flat, plaque-like structure and is characterized microscopically by acantholysis and dyskeratosis. Eccrine syringofibroadenomatous hyperplasia is benign and likely
Autor:
Waka Iwashita, Atsushi Kurabayashi, Chiharu Tanaka, Seiji Naganuma, Mutsuo Furihata, Fuminori Aki, Takanori Kawamura
Publikováno v:
International Journal of Surgical Pathology. 28:683-687
Superficial angiomyxoma is a rare, benign, multilobulated cutaneous tumor composed of stellate and spindle cells, a prominent myxoid matrix, and numerous blood vessels. Superficial angiomyxoma may be indistinguishable from cutaneous lesions of the Ca
Autor:
Chiharu Tanaka, Kaoru Furihata, Seiji Naganuma, Mitsunari Ogasawara, Reiko Yoshioka, Hideki Taniguchi, Mutsuo Furihata, Keisuke Taniuchi
Publikováno v:
Human cell. 35(2)
A well-established preclinical model of pancreatic cancer needs to be established to facilitate research on new therapeutic targets. Recently established animal models of pancreatic cancer, including patient-derived tumor models and organoid models,