Zobrazeno 1 - 10
of 606
pro vyhledávání: '"Seiji Shioda"'
Autor:
Weidong Zhang, Ayako Miura, Md Moin Abu Saleh, Koichiro Shimizu, Yuichiro Mita, Ryota Tanida, Satoshi Hirako, Seiji Shioda, Valery Gmyr, Julie Kerr-Conte, Francois Pattou, Chunhuan Jin, Yoshikatsu Kanai, Kazuki Sasaki, Naoto Minamino, Hideyuki Sakoda, Masamitsu Nakazato
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract Insulin secretion from pancreatic β cells is regulated by multiple stimuli, including nutrients, hormones, neuronal inputs, and local signalling. Amino acids modulate insulin secretion via amino acid transporters expressed on β cells. The
Externí odkaz:
https://doaj.org/article/13b28fe0aa5b471fb9ba3b62af44728f
Autor:
Masahiko Iwamoto, Tetsuya Kubota, Yoshitaka Sakurai, Nobuhiro Wada, Seiji Shioda, Toshimasa Yamauchi, Takashi Kadowaki, Naoto Kubota
Publikováno v:
Pharmacology Research & Perspectives, Vol 10, Iss 4, Pp n/a-n/a (2022)
Abstract Epidemiological and animal studies have revealed that sodium‐glucose cotransporter 2 (SGLT2) inhibitors suppress cardiovascular events in subjects with type 2 diabetes and atherosclerosis in animal models of diabetes. However, it still rem
Externí odkaz:
https://doaj.org/article/f9c72ebdee414566a987bfa6e7983cf8
Autor:
Junko Shibato, Fumiko Takenoya, Ai Kimura, Cheol Woo Min, Michio Yamashita, Ravi Gupta, Sun Tae Kim, Randeep Rakwal, Seiji Shioda
Publikováno v:
Molecules, Vol 28, Iss 4, p 1565 (2023)
The biological and psychological importance of hair is recognized worldwide. Molecules that can promote the activation of hair follicle stem cells and the initiation of the growth phase have been subjects of research. Clarifying how hair regeneration
Externí odkaz:
https://doaj.org/article/65ba1043be104e00915529ae62987cd3
Autor:
Chika Sawa, Sachiko Yofu, Keisuke Kiriyama, Keita Sutoh, Tomomi Saito, Satomi Kishi, Mariko Gunji, Yuriko Inoue, Masahito Sugi, Seiji Shioda, Kazuho Honda
Publikováno v:
Heliyon, Vol 7, Iss 11, Pp e08318- (2021)
Tumor necrosis frequently occurs in malignant tumors, showing rapid growth and invasion. This phenomenon is generally regarded as simple ischemic necrosis due to insufficient tumor vessels and blood supply. However, the necrotic tissue contains high
Externí odkaz:
https://doaj.org/article/69b0aad5d1f44e999dba242fae3d6fdd
Autor:
Taeko Kobayashi, Wenhui Piao, Toshiya Takamura, Hiroshi Kori, Hitoshi Miyachi, Satsuki Kitano, Yumiko Iwamoto, Mayumi Yamada, Itaru Imayoshi, Seiji Shioda, Andrea Ballabio, Ryoichiro Kageyama
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
It remains unclear why quiescent neural stem cells (qNSCs) in the subventricular zone of the mouse brain have enlarged lysosomes. Here, authors demonstrate that qNSCs exhibit higher lysosomal activity and degrade activated EGF receptor by endolysosom
Externí odkaz:
https://doaj.org/article/4691a3fa38a34ed4b3aef31a73471536
Autor:
Yuko S Niino, Ikuo Kawashima, Yoshinobu Iguchi, Hiroaki Kanda, Kiyoshi Ogura, Kaoru Mita-Yoshida, Tomio Ono, Maya Yamazaki, Kenji Sakimura, Satomi Yogosawa, Kiyotsugu Yoshida, Seiji Shioda, Takaya Gotoh
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0253912 (2021)
Protein kinase C-delta (PKCδ) has a caspase-3 recognition sequence in its structure, suggesting its involvement in apoptosis. In addition, PKCδ was recently reported to function as an anti-cancer factor. The generation of a PKCδ knockout mouse mod
Externí odkaz:
https://doaj.org/article/9aeae0a7358643b3bccee12c21878958
Autor:
Junko Shibato, Fumiko Takenoya, Takahiro Hirabayashi, Ai Kimura, Michio Yamashita, Ichiro Takasaki, Randeep Rakwal, Seiji Shioda
Publikováno v:
Neural Plasticity, Vol 2021 (2021)
The present research investigates the molecular mechanism of neurite outgrowth (protrusion elongation) under pituitary adenylate cyclase-activating polypeptide (PACAP) 38 treatments using a rat adrenal-derived pheochromocytoma cell line—PC12. This
Externí odkaz:
https://doaj.org/article/5b99d3b987a046d2bc6f1587bdcee2e9
Publikováno v:
Heliyon, Vol 6, Iss 4, Pp e03597- (2020)
Objective: Previous human and animal studies have shown that excessive maternal intake of folic acid (FA) predisposes to impaired glucose tolerance in the offspring. However, the underlying mechanism is unknown. Therefore, we aimed to determine wheth
Externí odkaz:
https://doaj.org/article/a85ca0b2293b46f78ba9548e2d75f789
Autor:
Ranjith Kumar Bakku, Ravi Gupta, Cheol-Woo Min, Sun-Tae Kim, Genboku Takahashi, Junko Shibato, Seiji Shioda, Fumiko Takenoya, Ganesh Kumar Agrawal, Randeep Rakwal
Publikováno v:
Molecules, Vol 27, Iss 3, p 1111 (2022)
The present research investigates the tuber proteome of the ‘medicinal’ plant Jerusalem artichoke (abbreviated as JA) (Helianthus tuberosus L.) using a high-throughput proteomics technique. Although JA has been historically known to the Native Am
Externí odkaz:
https://doaj.org/article/3f5e718a586d403b87f7ceba13eec6a1
Publikováno v:
The Journal of Headache and Pain, Vol 19, Iss 1, Pp 1-8 (2018)
Abstract Pituitary adenylate-cyclase-activating polypeptide (PACAP) is a 27- or 38-amino acid neuropeptide, which belongs to the vasoactive intestinal polypeptide (VIP)/glucagon/secretin family. PACAP shows particularly high homology (~ 68%) to VIP.
Externí odkaz:
https://doaj.org/article/526e728293124e56933e420271c461cc