Výsledky vyhledávání - "Seiichi Yusa"

Effective recovery of highly purified CD326(+) tumor cells from lavage fluid of patients treated with a novel cell-free and concentrated ascites reinfusion therapy (KM-CART)

Autor: Keisuke Matsusaki, Yukino Kimura, Seiichi Yusa, Yui Harada, Yoshikazu Yonemitsu, Takefumi Ishidao, Noriko Yasuda

Publikováno v: SpringerPlus

For the production of tumor-specific vaccines, including dendritic cell (DC) vaccines, the tumor cells themselves are an ideal source. Floating tumor cells in the ascites fluid from patients with malignant ascites are a good candidate source, but it

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eae86a636c3cee0adf68e1cd775c21ce
https://pubmed.ncbi.nlm.nih.gov/26702369

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Expression of normal cellular prion protein (PrP ) on T lymphocytes and the effect of copper ion: analysis by wild-type and prion protein gene-deficient mice

Autor: Takuya Nishimura, Takashi Onodera, Shigeyoshi Itohara, Akikazu Sakudo, Atsutaka Kubosaki, Keiichi Saeki, Yukiko Nishimura-Nasu, Yoshitsugu Matsumoto, Seiichi Yusa

Publikováno v: Biochemical and Biophysical Research Communications. 307:810-813

The purpose of this report was to determine the effect of prion protein (PrP) gene disruption on T lymphocyte function. Previous studies have suggested that normal cellular prion protein (PrP(c)) binds to copper and Cu(2+) is essential for interleuki

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d1d4c359c763ccf1823f01f76a9e48f
https://doi.org/10.1016/s0006-291x(03)01263-4

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Treatment with chemotherapy and dendritic cells pulsed with multiple Wilms' tumor 1 (WT1)-specific MHC class I/II-restricted epitopes for pancreatic cancer

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 20(16)

Purpose: We performed a phase I trial to investigate the safety, clinical responses, and Wilms' tumor 1 (WT1)-specific immune responses following treatment with dendritic cells (DC) pulsed with a mixture of three types of WT1 peptides, including both

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5db8f46fb1930157a45773ddf695d2c
https://pubmed.ncbi.nlm.nih.gov/25056373

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Prognostic factors related to add-on dendritic cell vaccines on patients with inoperable pancreatic cancer receiving chemotherapy: a multicenter analysis

Autor: Yoshikazu Yonemitsu, Sun-ichi Tsujitani, Hidenori Takahashi, Kazuhiro Nagai, Masahiro Ogasawara, Masaki Nagaya, Shigetaka Shimodaira, Seiichi Yusa, Junji Kishimoto, Mitsugu Tanii, Hirofumi Abe, Masato Okamoto, Yuta Shibamoto, Masanori Kobayashi, Takefumi Ishidao

Publikováno v: Cancer immunology, immunotherapy : CII. 63(8)

Dendritic cell (DC)-based cancer vaccines may have a significant benefit to patients with advanced pancreatic cancer. However, variations among clinical studies make it difficult to compare clinical outcomes. Here, we identified factors that determin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a1ae0b76c47bc87010a139f8d5abf64
https://pubmed.ncbi.nlm.nih.gov/24777613

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Distribution of Cellular Isoform of Prion Protein in T Lymphocytes and Bone Marrow, Analyzed by Wild-Type and Prion Protein Gene-Deficient Mice

Autor: Atsutaka Kubosaki, Takuya Nishimura, Seiichi Yusa, Yuko Nakamura, Yoshitsugu Matsumoto, Shigeyoshi Itohara, Takashi Onodera, Yukiko Nasu, Keiichi Saeki

Publikováno v: Biochemical and Biophysical Research Communications. 282:103-107

In this study, the authors investigated normal cellular prion protein (PrP C ) expression on murine immune systems using prion protein gene-deficient mouse as negative control. Immunocytes expressing PrP C in adult and fetal mice were detected by flo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::635b403d759d32f8424ed2fe5571bc4f
https://doi.org/10.1006/bbrc.2001.4538

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Abstract CT223: Dendritic cells pulsed with Wilms′ tumor gene 1 (WT1)-specific and MHC class I and II-restricted epitopes with gemcitabine induce antitumor immune responses in patients with advanced pancreatic cancer

Autor: Hiroshi Arakawa, Shigeo Koido, Kazuki Takakura, Hisao Tajiri, Shin Kan, Shigetaka Shimodaira, Kan Uchiyama, Seiichi Yusa, Sadamu Homma, Takafumi Ishidao, Kazumi Hayashi, Masato Okamoto, Shinji Yoshizaki, Toshifumi Ohkusa, Hiroo Imazu, Masako Mori, Mikio Kajihara

Publikováno v: Cancer Research. 74:CT223-CT223

Wilms' tumor gene 1 (WT1) protein is an attractive target for cancer immunotherapy. To evaluate whether dendritic cells (DCs) pulsed with WT1-specific and MHC class I and II-restricted epitopes in combination with gemcitabine induce antitumor immune

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8c5edff2e724cd8efad42c566fdd4453
https://doi.org/10.1158/1538-7445.am2014-ct223

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Autor: Masahiko Hatano, Mari Dezawa, Takeshi Tokuhisa, Seiichi Yusa, Hiroyuki Yamamoto, Yoichi Kohno, Yoshinori Iitsuka

Publikováno v: Anatomy and embryology. 195(5)

We have isolated the murine homeobox gene (Ncx) that belong to a Hox11 gene family. Expression of the Ncx gene was analyzed in total RNAs from embryos by reverse transcribed polymerase chain reaction (RT-PCR). The mRNA was detected in embryos after 9

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae7053ebe2f45c3da12cb520acfae8d4
https://pubmed.ncbi.nlm.nih.gov/9176664

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