Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Seiichi Tsukamoto"'
Autor:
Fumihito Miura, Yasuhiro Kodera, Yusuke Matsui, Kenji Shiraishi, Makoto Suzuki, Tomoko Saito, Hiromitsu Araki, Aya Komine, Shuhei Ito, Seiichi Tsukamoto, Kuniaki Sato, Koshi Mimori, Atsushi Niida, Mitsuko Fukunaga, Takaaki Masuda, Akihiro Kitagawa, Dai Shimizu, Nobuyoshi Akimitsu, Hiroshi Haeno, Yuji Miyamoto, Kenzui Taniue, Yukihiro Yoshikawa, Takashi Ito, Hideo Baba, Yuta Kobayashi
Publikováno v:
Cancer Gene Therapy. 29:428-436
The accurate and early diagnosis and classification of cancer origin from either tissue or liquid biopsy is crucial for selecting the appropriate treatment and reducing cancer-related mortality. Here, we established the CAncer Cell-of-Origin (CACO) m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2691cbebafb7e9a8a0e64fef2c720e74
https://doi.org/10.1038/s41417-021-00401-w
https://doi.org/10.1038/s41417-021-00401-w
Autor:
Dai, Shimizu, Kenzui, Taniue, Yusuke, Matsui, Hiroshi, Haeno, Hiromitsu, Araki, Fumihito, Miura, Mitsuko, Fukunaga, Kenji, Shiraishi, Yuji, Miyamoto, Seiichi, Tsukamoto, Aya, Komine, Yuta, Kobayashi, Akihiro, Kitagawa, Yukihiro, Yoshikawa, Kuniaki, Sato, Tomoko, Saito, Shuhei, Ito, Takaaki, Masuda, Atsushi, Niida, Makoto, Suzuki, Hideo, Baba, Takashi, Ito, Nobuyoshi, Akimitsu, Yasuhiro, Kodera, Koshi, Mimori
Publikováno v:
Cancer gene therapy. 29(5)
The accurate and early diagnosis and classification of cancer origin from either tissue or liquid biopsy is crucial for selecting the appropriate treatment and reducing cancer-related mortality. Here, we established the CAncer Cell-of-Origin (CACO) m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d2d4035f30fe47291920ad6666fa45cd
https://pubmed.ncbi.nlm.nih.gov/34744163
https://pubmed.ncbi.nlm.nih.gov/34744163
Autor:
Teruyuki Fujii, Seiichi Tsukamoto, Seine A. Shintani, Takako Terui, Shin'ichi Ishiwata, Yasuharu Kushida, Norio Fukuda, Erisa Hirokawa, Fuyu Kobirumaki-Shimozawa, Togo Shimozawa, Kotaro Oyama
Publikováno v:
Progress in Biophysics and Molecular Biology. 124:31-40
The cardiac pump function is a result of a rise in intracellular Ca2+ and the ensuing sarcomeric contractions [i.e., excitation-contraction (EC) coupling] in myocytes in various locations of the heart. In order to elucidate the heart's mechanical pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25712c77a178283b92d627539853fb31
https://doi.org/10.1016/j.pbiomolbio.2016.09.006
https://doi.org/10.1016/j.pbiomolbio.2016.09.006
Autor:
Cristobal G. dos Remedios, Fuyu Kobirumaki-Shimozawa, Shin'ichi Ishiwata, Amy Li, Mitsunori Yamane, Seiichi Tsukamoto, Tatsuya Kagemoto, Kotaro Oyama, Norio Fukuda
Publikováno v:
Circulation: Heart Failure. 11
Background: Left ventricular wall motion is depressed in patients with dilated cardiomyopathy (DCM). However, whether or not the depressed left ventricular wall motion is caused by impairment of sarcomere dynamics remains to be fully clarified. Metho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d9393e0bba38041b04c467a1bb2b357
https://doi.org/10.1161/circheartfailure.117.004333
https://doi.org/10.1161/circheartfailure.117.004333
Publikováno v:
Biochemistry. 53:3858-3866
Many studies have shown that during the early stages of the folding of a protein, chain collapse and secondary structure formation lead to a partially folded intermediate. Thus, direct observation of these early folding events is crucial if we are to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a22e1270cd15137ee1ad811286fbeaf5
https://doi.org/10.1021/bi5003647
https://doi.org/10.1021/bi5003647
Autor:
Seiichi Tsukamoto, Kotaro Oyama, Togo Shimozawa, Seine A. Shintani, Shin'ichi Ishiwata, Fuyu Kobirumaki-Shimozawa, Norio Fukuda, Teruyuki Fujii
Publikováno v:
Biophysical Journal. 110(3)
In the present study, we developed a novel experimental system for simultaneous measurement of changes in the intracellular Ca2+ concentration ([Ca2+]i) at local areas of the T-tubules / Z-discs and single sarcomere length (SL) via expression of FRET
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aab7c377b12b2c2b82f8df2730edac56
Publikováno v:
Journal of Biochemistry. 146:343-350
A variant of human tear lipocalin was expressed in Escherichia coli, and the bound fatty acids were analysed by gas chromatography, mass spectroscopy and nuclear magnetic resonance spectroscopy. Five major fatty acids were identified as hexadecanoic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b981da2966fe981e30bbc4059ee1a937
https://doi.org/10.1093/jb/mvp076
https://doi.org/10.1093/jb/mvp076
Autor:
Takeo Yajima, Yoshiteru Yamada, Kanako Nakagawa, Hiroshi Kihara, Seiichi Tsukamoto, Kazuo Fujiwara, Masamichi Ikeguchi
Publikováno v:
Journal of Applied Crystallography. 40:s213-s216
The chloride-ion concentration dependence of the molecular dimension in the acid-denatured state of equine β-lactoglobulin (ELG) was investigated by small-angle X-ray scattering. In the presence of chloride ion, ELG has a globular and compact confor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b40f3c05924ba0ef5f79f02238c9372
https://doi.org/10.1107/s0021889807008278
https://doi.org/10.1107/s0021889807008278
Autor:
Masamichi Ikeguchi, Seiichi Tsukamoto, Kazuo Fujiwara, Takahiro Okabe, Toshiaki Miyajima, Kanako Nakagawa
Publikováno v:
Journal of biochemistry. 156(5)
β-lactoglobulin forms a non-native α-helix during an early stage of folding. To address the role of the non-native structure in the folding process, we designed several mutants of equine β-lactoglobulin with reduced helical propensity in the non-n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bb3611f228da44b3f81b0848fd753b6
https://pubmed.ncbi.nlm.nih.gov/24947560
https://pubmed.ncbi.nlm.nih.gov/24947560
Autor:
Kanako, Nakagawa, Yoshiteru, Yamada, Yoshitaka, Matsumura, Seiichi, Tsukamoto, Mio, Yamamoto-Ohtomo, Hideaki, Ohtomo, Takahiro, Okabe, Kazuo, Fujiwara, Masamichi, Ikeguchi
Publikováno v:
Biopolymers. 101(6)
Chain collapse and secondary structure formation are frequently observed during the early stages of protein folding. Is the chain collapse brought about by interactions between secondary structure units or is it due to polymer behavior in a poor solv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::112ef521bce507b646e68c6126d8e9f0
https://pubmed.ncbi.nlm.nih.gov/25100622
https://pubmed.ncbi.nlm.nih.gov/25100622