Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Seiichi, Iizuka"'
Autor:
Hiroaki Oizumi, Yuki Miyamoto, Chika Seiwa, Masahiro Yamamoto, Nozomu Yoshioka, Seiichi Iizuka, Tomohiro Torii, Katsuya Ohbuchi, Kazushige Mizoguchi, Junji Yamauchi, Hiroaki Asou
Publikováno v:
iScience, Vol 26, Iss 10, Pp 107448- (2023)
Summary: Multiple sclerosis (MS) is a leading disease that causes disability in young adults. We have previously shown that a DEAD-box RNA helicase Ddx54 binds to mRNA and protein isoforms of myelin basic protein (MBP) and that Ddx54 siRNA blocking a
Externí odkaz:
https://doaj.org/article/63a42a4946ca499fb147b3974ca292f5
Autor:
Miwa Nahata, Sachiko Mogami, Hitomi Sekine, Seiichi Iizuka, Naoto Okubo, Naoki Fujitsuka, Hiroshi Takeda
Publikováno v:
npj Aging and Mechanisms of Disease, Vol 7, Iss 1, Pp 1-14 (2021)
Abstract Chronic undernutrition contributes to the increase in frailty observed among elderly adults, which is a pressing issue in the sector of health care for older people worldwide. Autophagy, an intracellular recycling system, is closely associat
Externí odkaz:
https://doaj.org/article/2976f3861c604a40a8c972724066b04e
Autor:
Akinori Nishi, Noriko Kaifuchi, Chika Shimobori, Katsuya Ohbuchi, Seiichi Iizuka, Aiko Sugiyama, Keisuke Ogura, Masahiro Yamamoto, Haruo Kuroki, Shigeki Nabeshima, Ayako Yachie, Yukiko Matsuoka, Hiroaki Kitano
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-19 (2021)
Abstract Maoto, a traditional kampo medicine, has been clinically prescribed for influenza infection and is reported to relieve symptoms and tissue damage. In this study, we evaluated the effects of maoto as an herbal multi-compound medicine on host
Externí odkaz:
https://doaj.org/article/b5861bd758d54473b0e9cfbbe5346d2a
Autor:
Miwa Nahata, Naoki Fujitsuka, Hitomi Sekine, Chika Shimobori, Katsuya Ohbuchi, Seiichi Iizuka, Sachiko Mogami, Shunsuke Ohnishi, Hiroshi Takeda
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Malnutrition impairs basic daily activities and leads to physical frailty, which is aggravated in the elderly compared with young adults. It is also well-known that the elderly are more vulnerable to metabolic stress. Therefore, in this study, using
Externí odkaz:
https://doaj.org/article/826f08799ed24f58a4c998facfea729e
Autor:
Yumi Harada, Hitomi Sekine, Kunitsugu Kubota, Daichi Sadatomi, Seiichi Iizuka, Naoki Fujitsuka
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 141, Iss , Pp 111860- (2021)
EGFR tyrosine kinase inhibitors (TKIs) are mainly used to treat non-small cell lung cancer; however, adverse effects such as severe diarrhea represent a major obstacle towards the continuation of EGFR-TKIs therapy. Chloride channels, which control th
Externí odkaz:
https://doaj.org/article/f7fd0d0cf52a4ee58a9b95b1c6bf2a17
Autor:
Mitsue Nishiyama, Nobuhiro Ohtake, Atsushi Kaneko, Naoko Tsuchiya, Sachiko Imamura, Seiichi Iizuka, Shiori Ishizawa, Akinori Nishi, Masahiro Yamamoto, Akinobu Taketomi, Toru Kono
Publikováno v:
Nutrients, Vol 12, Iss 3, p 839 (2020)
Non-alcoholic fatty liver disease (NAFLD) is considered a worldwide healthcare problem that mirrors the increased prevalence of obesity. Gut microbiota plays a crucial role in the progression and treatment of NAFLD. Bofutsushosan (BTS), a pharmaceuti
Externí odkaz:
https://doaj.org/article/a113859c46b04d4ca5dd6e718a105694
Autor:
Shiori Ishizawa, Akinori Nishi, Noriko Kaifuchi, Chika Shimobori, Miwa Nahata, Chihiro Yamada, Seiichi Iizuka, Katsuya Ohbuchi, Mitsue Nishiyama, Naoki Fujitsuka, Toru Kono, Masahiro Yamamoto
Publikováno v:
Gene. 846
Dysregulation of lipid metabolism and diabetes are risk factors for nonalcoholic fatty liver disease (NAFLD), and the gut-liver axis and intestinal microbiome are known to be highly associated with the pathogenesis of this disease. In Japan, the trad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f79e804e422219c7ee19547fe426099b
https://pubmed.ncbi.nlm.nih.gov/36067864
https://pubmed.ncbi.nlm.nih.gov/36067864
Publikováno v:
British Journal of Pharmacology
Background and Purpose Women have a higher incidence of eating disorders than men. We investigated whether the effects of ghrelin on feeding are affected by sex and stress, and to elucidate the mechanisms that may cause sex differences in stress‐me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d776c6bf426cea3d6357c3810634bff4
http://hdl.handle.net/2115/79574
http://hdl.handle.net/2115/79574
Autor:
Koichi Tsuneyama, Yen-Chen Chen, Makoto Fujimoto, Yoshiyuki Sasaki, Wataru Suzuki, Tsutomu Shimada, Seiichi Iizuka, Mitsunobu Nagata, Masaki Aburada, Shao-Yuan Chen
Publikováno v:
The Scientific World Journal, Vol 11, Pp 2124-2135 (2011)
The effect of hyperbaric oxygen treatment (HBOT) was examined using MSG mice, which are an animal model of obesity, hyperlipidemia, diabetes, and nonalcoholic fatty liver disease. Nineteen MSG male mice were divided into HBOT treated and control grou
Externí odkaz:
https://doaj.org/article/e1ff57c336f54aa6a9ec47a29b9f2e48
Autor:
Yohei Tokita, Masahiro Yamamoto, Kazuko Satoh, Mitsue Nishiyama, Seiichi Iizuka, Sachiko Imamura, Yoshio Kase
Publikováno v:
Journal of Pharmacological Sciences, Vol 115, Iss 1, Pp 75-83 (2011)
This study focused on the localization of transient receptor potential vanilloid type 1 (TRPV1) in the intestines in postoperative adhesion model rats and investigated the underlying mechanism for the anti-adhesion action of daikenchuto (DKT), especi
Externí odkaz:
https://doaj.org/article/07799087cd324e4ba7f338c088a1425a