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Autor:
Kuniaki Saito, Tomihiko Uemura, Seiich Haga, Kumiko Hirai, Susumu Izumi, Hidehito Kuroyanagi, Yoshitaka Tatebayashi, Yoshitaka Hayashi, Kanako Hirabayashi-Takahashi
Publikováno v:
Journal of Biochemistry. 148:639-650
L-kynurenine 3-monooxygenase (KMO) is an NAD(P)H-dependent flavin monooxygenase that catalyses the hydroxylation of L -kynurenine to 3-hydroxykynurenine, and is localized as an oligomer in the mitochondrial outer membrane. In the human brain, KMO may