Výsledky vyhledávání - "Seigo Sugiyama"

Akademický článek

Elevation of the renal threshold for glucose is associated with insulin resistance and higher glycated hemoglobin levels

Autor: Kunio Hieshima, Seigo Sugiyama, Akira Yoshida, Noboru Kurinami, Tomoko Suzuki, Hiroko Ijima, Fumio Miyamoto, Keizo Kajiwara, Katsunori Jinnouchi, Tomio Jinnouchi, Hideaki Jinnouchi

Publikováno v: Journal of Diabetes Investigation, Vol 11, Iss 3, Pp 617-625 (2020)

Abstract Aims/Introduction The renal threshold for glucose (RTg) corresponds to a blood glucose level of ~180 mg/dL; however, in hospitals, patients are often encountered who are hyperglycemic, but urine glucose test strip‐negative, who remain nega

Externí odkaz: https://doaj.org/article/ea9220535e6942029004990f72a09126

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Akademický článek

Rationale and design of a multicenter placebo-controlled double-blind randomized trial to evaluate the effect of empagliflozin on endothelial function: the EMBLEM trial

Publikováno v: Cardiovascular Diabetology, Vol 16, Iss 1, Pp 1-12 (2017)

Abstract Background Type 2 diabetes mellitus (T2DM) is characterized by systemic metabolic abnormalities and the development of micro- and macrovascular complications, resulting in a shortened life expectancy. A recent cardiovascular (CV) safety tria

Externí odkaz: https://doaj.org/article/03047384b5c34598bbc3090a5fe2a771

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Akademický článek

Impaired Peripheral Endothelial Function Assessed by Digital Reactive Hyperemia Peripheral Arterial Tonometry and Risk of In‐Stent Restenosis

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 6 (2016)

BackgroundDrug‐eluting stents are replacing bare‐metal stents, but in‐stent restenosis (ISR) remains a problem. Reactive hyperemia index (RHI) assessed by peripheral arterial tonometry evaluates endothelial function noninvasively. We prospectiv

Externí odkaz: https://doaj.org/article/cd60a8e2e9324d24bb152f7d8a0a4ffc

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Akademický článek

Liraglutide, a Glucagon-Like Peptide-1 Analog, Increased Insulin Sensitivity Assessed by Hyperinsulinemic-Euglycemic Clamp Examination in Patients with Uncontrolled Type 2 Diabetes Mellitus

Autor: Hideaki Jinnouchi, Seigo Sugiyama, Akira Yoshida, Kunio Hieshima, Noboru Kurinami, Tomoko Suzuki, Fumio Miyamoto, Keizo Kajiwara, Kunihiko Matsui, Tomio Jinnouchi

Publikováno v: Journal of Diabetes Research, Vol 2015 (2015)

Aims. Glucagon-like peptide-1 (GLP-1) analog promotes insulin secretion by acting on pancreatic β-cells. This antihyperglycemic treatment for type 2 diabetes mellitus (DM) has attracted increased clinical attention not only for its antihyperglycemic

Externí odkaz: https://doaj.org/article/997933f938f24c579d57859cb800a18d

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Akademický článek

Basal and ischemia-induced transcardiac troponin release into the coronary circulation in patients with suspected coronary artery disease.

Autor: Masaaki Konishi, Seigo Sugiyama, Koichi Sugamura, Toshimitsu Nozaki, Keisuke Ohba, Junichi Matsubara, Kenji Sakamoto, Yasuhiro Nagayoshi, Hitoshi Sumida, Eiichi Akiyama, Yasushi Matsuzawa, Kentaro Sakamaki, Satoshi Morita, Kazuo Kimura, Satoshi Umemura, Hisao Ogawa

Publikováno v: PLoS ONE, Vol 8, Iss 4, p e60163 (2013)

BACKGROUND: Cardiac troponin is a specific biomarker for cardiomyocyte necrosis in acute coronary syndromes. Troponin release from the coronary circulation remains to be determined because of the lower sensitivity of the conventional assay. We sought

Externí odkaz: https://doaj.org/article/b05a736d4fcf4a71b59b726a2c062386

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Akademický článek

Combination treatment of rosuvastatin or atorvastatin, with regular exercise improves arterial wall stiffness in patients with coronary artery disease.

Autor: Kensuke Toyama, Seigo Sugiyama, Hideki Oka, Yuri Iwasaki, Hitoshi Sumida, Tomoko Tanaka, Shinji Tayama, Hideaki Jinnouchi, Hisao Ogawa

Publikováno v: PLoS ONE, Vol 7, Iss 7, p e41369 (2012)

OBJECTIVE: Statin- and exercise-therapy are both clinically beneficial by preventing cardiovascular events in patients with coronary artery disease (CAD). However, there is no information on the vascular effects of the combination of statins and exer

Externí odkaz: https://doaj.org/article/9a823b576969470fb37fea1967ebc057

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