Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Seigo, Iwakawa"'
Autor:
Shota Tanaka, Mika Hosokawa, Takumi Miyamoto, Aiko Nakagawa, Mika Haruna, Kumiko Ueda, Seigo Iwakawa, Ken-ichi Ogawara
Publikováno v:
Biochemistry and Biophysics Reports, Vol 26, Iss , Pp 100996- (2021)
microRNAs (miRNAs) contained in small extracellular vesicles (sEVs) are candidates for non-invasive biomarkers. Oxaliplatin (L-OHP) has been approved for advanced colorectal cancer (CRC) chemotherapy. However, the response to L-OHP differs among CRC
Externí odkaz:
https://doaj.org/article/0628385de8e242989e0303c525fd387d
Publikováno v:
Biochemical and Biophysical Research Communications. 578:157-162
Decitabine (DAC), a DNA methyltransferase (DNMT) inhibitor is a novel anti-cancer drug regulating epigenetic mechanisms. Similar to conventional anti-cancer drugs, drug resistance to DAC also has been reported, resulting in tumor recurrence. Our prev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab51794025123e4ffb8d17ca03d64b9a
https://doi.org/10.1016/j.bbrc.2021.09.041
https://doi.org/10.1016/j.bbrc.2021.09.041
Publikováno v:
Drug Metabolism and Pharmacokinetics. 35:124-130
Decitabine (DAC), a DNA methylation inhibitor, is transported into cancer cells mainly via equilibrative nucleoside transporter 1 (ENT1) and subsequently phosphorylated by deoxycytidine kinase (dCK). We previously reported that apparent DAC uptake in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1aed95c3e8badd06a6701ff51a2975f
https://doi.org/10.1016/j.dmpk.2019.10.002
https://doi.org/10.1016/j.dmpk.2019.10.002
Publikováno v:
Biochemical and Biophysical Research Communications. 509:249-254
Epigenetic modifiers such as decitabine (DAC), a DNA methyltransferase inhibitor, have the potential benefit of combination therapy with conventional anti-cancer drugs. This study was aimed to clarify whether DAC at the low concentration without cyto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47c2703389178849a29575427eefe422
https://doi.org/10.1016/j.bbrc.2018.12.115
https://doi.org/10.1016/j.bbrc.2018.12.115
Publikováno v:
Chemicalpharmaceutical bulletin. 68(12)
The aim of this study was to investigate appropriate analytical conditions for hydrophilic nucleosides and nucleotides (monophosphates and triphosphates) by HPLC methods using a mixed-mode AX-C18 column with anion-exchange and hydrophobic interaction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6122fd9f4ee7b50a960b59cb1016a12
https://pubmed.ncbi.nlm.nih.gov/33268655
https://pubmed.ncbi.nlm.nih.gov/33268655
Publikováno v:
Biological and Pharmaceutical Bulletin. 41:277-280
Human serum albumin (HSA) has two major ligand-binding sites, sites I and II, and hydrolyzes compounds at both sites. Although the hydrolytic interaction of ester-type drugs with other drugs by HSA has been reported, there are only a few studies conc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d67b3bdb5967f54e1600f45f862d6a6c
https://doi.org/10.1248/bpb.b17-00680
https://doi.org/10.1248/bpb.b17-00680
Autor:
Takeshi Tomida, Manabu Kume, Tatsuya Nishioka, Shuji Kitagawa, Hiroo Makimoto, Ikuko Yano, Tomoyuki Sakaue, Tsuneo Hamaguchi, Atsushi Uda, Aiko Ishikawa, Akira Nozaki, Seigo Iwakawa, Midori Hirai
Publikováno v:
医療薬学. 44(4):157-164
Kobe University Hospital created a simplified 14-item protocol for resolving out-of-hospital prescription queries. The protocol was implemented in September 2016 in nine community pharmacies. If prescriptions were changed as per the new protocol or v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48f9181be12deb1bbdf371108c34e906
http://www.lib.kobe-u.ac.jp/handle_kernel/90006434
http://www.lib.kobe-u.ac.jp/handle_kernel/90006434
Autor:
Takumi Miyamoto, Shota Tanaka, Ken-ichi Ogawara, Mika Hosokawa, Kumiko Ueda, Mika Haruna, Aiko Nakagawa, Seigo Iwakawa
Publikováno v:
Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports, Vol 26, Iss, Pp 100996-(2021)
Biochemistry and Biophysics Reports, Vol 26, Iss, Pp 100996-(2021)
microRNAs (miRNAs) contained in small extracellular vesicles (sEVs) are candidates for non-invasive biomarkers. Oxaliplatin (L-OHP) has been approved for advanced colorectal cancer (CRC) chemotherapy. However, the response to L-OHP differs among CRC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5bcfe0ae4d8b11f68d61f72f9c26461
https://doi.org/10.1016/j.bbrep.2021.100996
https://doi.org/10.1016/j.bbrep.2021.100996
Publikováno v:
Biological & Pharmaceutical Bulletin. 40:2199-2204
Limited information is currently available on how to apply epigenetic modifiers to current colorectal cancer (CRC) chemotherapy. The purpose of this study is to clarify the schedule-dependent effects of combined treatment with conventional anticancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e0fbbe22300ce17f47d8763da6282f2
https://doi.org/10.1248/bpb.b17-00439
https://doi.org/10.1248/bpb.b17-00439
Autor:
Norio Masumoto, Kunihiko Hashimoto, Shogo Kurebayashi, Satoko Suzuki, Shinya Inada, Hiroaki Otsuki, Masafumi Koga, Seigo Iwakawa, Kayoko Goya, Hiroyuki Sho
Publikováno v:
Diabetology International. 8:212-217
The ratio of glycated albumin (GA) to HbA1c (the GA/HbA1c ratio) has been used as a glycemic control indicator that reflects postprandial plasma glucose levels or glycemic variability. In this study, we investigated the effects of alogliptin, a DPP-4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09d6a6ef3be409fc84bbc88fdd3e92ab
https://doi.org/10.1007/s13340-016-0298-3
https://doi.org/10.1007/s13340-016-0298-3