Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Sei Kumakura"'
Publikováno v:
Renal Failure, Vol 41, Iss 1, Pp 47-56 (2019)
AST-120 (KREMEZIN®) consists of oral, spherical carbon particles that adsorb uremic toxins and their precursors within the gastrointestinal tract, allowing them to be excreted in the feces. Uremic toxins such as indoxyl sulfate and p-cresyl sulfate
Externí odkaz:
https://doaj.org/article/2937b596faca4e9ab1fd48f8c0d5e5d3
Publikováno v:
Renal Failure, Vol 41, Iss 1, Pp 47-56 (2019)
AST-120 (KREMEZIN®) consists of oral, spherical carbon particles that adsorb uremic toxins and their precursors within the gastrointestinal tract, allowing them to be excreted in the feces. Uremic toxins such as indoxyl sulfate and p-cresyl sulfate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e01ea2f8b24521b8999f696f65ffc30b
https://doi.org/10.1080/0886022x.2018.1561376
https://doi.org/10.1080/0886022x.2018.1561376
Autor:
Hironori Sato, Sei Kumakura, Naoki Yamamoto, Tetsuro Matano, Tsutomu Murakami, Yosuke Maeda, Yuta Hikichi, Taichiro Takemura, Masayuki Fujino, Masaru Yokoyama
Publikováno v:
The Journal of general virology. 97(9)
HIV-1 passage in cell culture in the presence of chemokine receptor antagonists can result in selection of viruses with env mutations that confer resistance to these inhibitors. In the present study, we examined the effect of HIV-1env mutations that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::711692c60c6f31a07e43fbae6bde066d
https://pubmed.ncbi.nlm.nih.gov/27368421
https://pubmed.ncbi.nlm.nih.gov/27368421
Autor:
Yuetsu Tanaka, Reiko Tanaka, Mikiro Yanaka, Kazu Okuma, Masako Nishizawa, Mamoru Ito, Naoki Yamamoto, Wataru Sugiura, Tomoyuki Ogura, Sei Kumakura
Publikováno v:
The Journal of Infectious Diseases. 197:134-141
CXCR4-tropic (X4) human immunodeficiency virus type 1 (HIV-1) does not efficiently infect and replicate in severe combined immunodeficiency (SCID) mice reconstituted with human peripheral blood mononuclear cells, termed "hu-PBL-SCID mice," due to, at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0acfc06c1fcdab0817288a2706036c8
https://doi.org/10.1086/524303
https://doi.org/10.1086/524303
Publikováno v:
Medical microbiology and immunology. 202(2)
We evaluated the long-term effects of the single oral administration of a new CXCR4 antagonist, KRH-3955, on elevation of white blood cell (WBC), neutrophil and lymphocyte counts in normal cynomolgus monkeys. In the monkeys treated with 0, 2, 20, 200
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c50021c840b986c185a7b2ec4525dc7
https://pubmed.ncbi.nlm.nih.gov/22772800
https://pubmed.ncbi.nlm.nih.gov/22772800
Autor:
Jun Komano, Reiko Tanaka, Yuetsu Tanaka, Toru Yamazaki, Sei Kumakura, Wei Huang, Naoki Yamamoto, Tsutomu Murakami, Makiko Hamatake, Kazu Okuma, Jonathan Toma, Mikiro Yanaka
The previously reported CXCR4 antagonist KRH-1636 was a potent and selective inhibitor of CXCR4-using (X4) human immunodeficiency virus type 1 (HIV-1) but could not be further developed as an anti-HIV-1 agent because of its poor oral bioavailability.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::141d0e3a89e2cabe8cb971a92f89946f
https://europepmc.org/articles/PMC2704660/
https://europepmc.org/articles/PMC2704660/
