Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Sehyun, Chae"'
Autor:
Sehyun Chae, Hyun-ju Lee, Ha-Eun Lee, Jieun Kim, Yoo Joo Jeong, Yuxi Lin, Hye Yun Kim, Geoffray Leriche, Rachel S. Ehrlich, Sascha Castro Lingl, Min-Duk Seo, Young-Ho Lee, Jerry Yang, Jae-Ick Kim, Hyang-Sook Hoe
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-34 (2024)
Abstract Background We recently reported that the dopamine (DA) analogue CA140 modulates neuroinflammatory responses in lipopolysaccharide-injected wild-type (WT) mice and in 3-month-old 5xFAD mice, a model of Alzheimer’s disease (AD). However, the
Externí odkaz:
https://doaj.org/article/320a17cb8a82451c8f0b059ff0d03f14
Autor:
Jong Hyuk Yoon, Dongha Lee, Chany Lee, Eunji Cho, Seulah Lee, Amaury Cazenave-Gassiot, Kipom Kim, Sehyun Chae, Edward A. Dennis, Pann-Ghill Suh
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 5, Pp 1043-1054 (2024)
Abstract Biomedical research on the brain has led to many discoveries and developments, such as understanding human consciousness and the mind and overcoming brain diseases. However, historical biomedical research on the brain has unique characterist
Externí odkaz:
https://doaj.org/article/4a4b038fd58945099e89b00aa1e37063
Autor:
Jiye Choi, Seungmoon Jung, Jieun Kim, Dahm So, Arie Kim, Sowon Kim, Sungjoon Choi, Eunsu Yoo, Jee Yeon Kim, Yoon Cheol Jang, Hyoin Lee, Jeongyeon Kim, Hee-Sup Shin, Sehyun Chae, Sehoon Keum
Publikováno v:
Cell Reports, Vol 43, Iss 9, Pp 114659- (2024)
Summary: Empathy, crucial for social interaction, is impaired across various neuropsychiatric conditions. However, the genetic and neural underpinnings of empathy variability remain elusive. By combining forward genetic mapping with transcriptome ana
Externí odkaz:
https://doaj.org/article/a8b63d774700496d889444263a14e779
Autor:
Jeongsoo Kim, Tae-Jin Kim, Sehyun Chae, Hyojeong Ha, Yejin Park, Sunghee Park, Chul Joo Yoon, Seon Ah Lim, Hyemin Lee, Jiyoung Kim, Jungwon Kim, Kyungtaek Im, Kyunghye Lee, Jeongmin Kim, Daham Kim, Eunju Lee, Min Hwa Shin, Serk In Park, Inmoo Rhee, Keehoon Jung, Jeewon Lee, Keun Hwa Lee, Daehee Hwang, Kyung-Mi Lee
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-21 (2024)
Abstract Background In the myeloid compartment of the tumor microenvironment, CD244 signaling has been implicated in immunosuppressive phenotype of monocytes. However, the precise molecular mechanism and contribution of CD244 to tumor immunity in mon
Externí odkaz:
https://doaj.org/article/b9d69d09111a49bdb32d80e3ebb65c32
Autor:
Somin Lee, Hyunkyung Kim, Bum Suk Kim, Sehyun Chae, Sangmin Jung, Jung Seub Lee, James Yu, Kyungmin Son, Minhwan Chung, Jong Kyoung Kim, Daehee Hwang, Sung Hee Baek, Noo Li Jeon
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Several functions of autophagy associated with proliferation, differentiation, and migration of endothelial cells have been reported. Due to lack of models recapitulating angiogenic sprouting, functional heterogeneity of autophagy in endothe
Externí odkaz:
https://doaj.org/article/aa9f3fd8ad304ab0a6941c90ed022c38
Autor:
Seungbo Yoo, Yun Hee Jeong, Hong-Hee Choi, Sehyun Chae, Daehee Hwang, Sung Jae Shin, Sang-Jun Ha
Publikováno v:
Experimental and Molecular Medicine, Vol 55, Iss 5, Pp 999-1012 (2023)
Abstract Chronic viral infection impairs systemic immunity in the host; however, the mechanism underlying the dysfunction of immune cells in chronic viral infection is incompletely understood. In this study, we studied the lineage differentiation of
Externí odkaz:
https://doaj.org/article/2d70b49057364b869f851817bfc7cd93
Autor:
Sehyun Chae, Jieun Kim
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S301-S302 (2023)
Externí odkaz:
https://doaj.org/article/32bf8da31d154afc8295d946b610f1a4
Autor:
Ji-Hye Oh, Sungyang Jo, Kye Won Park, Eun-Jae Lee, Seung Hyun Lee, Yun Su Hwang, Ha Ra Jeon, Yeonjin Ryu, Hee Jeong Yoon, Sung-Min Chun, Chong Jai Kim, Tae Won Kim, Chang Ohk Sung, Sehyun Chae, Sun Ju Chung
Publikováno v:
Experimental and Molecular Medicine, Vol 55, Iss 3, Pp 555-564 (2023)
Parkinson’s disease: genetic risk factors in a Korean population A whole-genome sequencing study of Korean individuals with Parkinson’s disease (PD) has identified several new genetic risk factors, ranging from single nucleotide variations (SNVs)
Externí odkaz:
https://doaj.org/article/427f9743ab9b42ca99fb560c6a692102
Autor:
Jieun Kim, Jung-Youn Han, Yujeong Lee, Kipom Kim, Young Pyo Choi, Sehyun Chae, Hyang-Sook Hoe
Publikováno v:
Molecular Brain, Vol 16, Iss 1, Pp 1-5 (2023)
Abstract Studies of mouse models of Alzheimer's disease (AD) have demonstrated that nitric oxide synthase 2 (NOS2) is involved in AD pathology. However, the effects of NOS2 on the pathology of Parkinson’s disease (PD) are not well studied. To addre
Externí odkaz:
https://doaj.org/article/967a425a63384093990557041393fc7c
Autor:
Sofia Brito, Hyojin Heo, Byungsun Cha, Su-Hyun Lee, Sehyun Chae, Mi-Gi Lee, Byeong-Mun Kwak, Bum-Ho Bin
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Spermidine (SPD), a polyamine naturally present in living organisms, is known to prolong the lifespan of animals. In this study, the role of SPD in melanogenesis was investigated, showing potential as a pigmenting agent. SPD treatment increa
Externí odkaz:
https://doaj.org/article/a09c3963f2014fd29346de1ddd14b5ec