Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Sehoon Won"'
Autor:
Michael A. Bemben, Matthew A. Sandoval, Aliza A. Le, Sehoon Won, Vivian N Chau, Julie C. Lauterborn, Salvatore Incontro, Kathy H. Li, Alma L. Burlingame, Katherine W. Roche, Christine M. Gall, Roger A. Nicoll, Javier Diaz-Alonso
Neurodevelopmental disorders are frequently linked to mutations in synaptic organizing molecules. MAM domain containing glycosylphosphatidylinositol anchor 1 and 2 (MDGA1 and MDGA2) are a family of synaptic organizers suggested to play an unusual rol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41ca99f368ad139fcfa61e0d6f1fcb49
https://doi.org/10.1101/2023.05.25.542333
https://doi.org/10.1101/2023.05.25.542333
Autor:
Sehoon Won, Katie S. Kindt, Hiu-Tung C. Wong, Amrita Mandal, Natalie Mosqueda, Katherine Pinter, Catherine M. Drerup, Alisha Beirl, Richa Madan Lomash
Publikováno v:
The Journal of Neuroscience
In neurons, mitochondria are transported by molecular motors throughout the cell to form and maintain functional neural connections. These organelles have many critical functions in neurons and are of high interest as their dysfunction is associated
Autor:
Stephanie B. Seminara, Greti Aguilera, Tim Cheetham, Richard Quinton, Ellen W. Leschek, Angela Delaney, Katherine W. Roche, Sehoon Won, Melissa Jennings, Kevin M. Barnes, Philip Whalen, Shanna Yue, Matthew G. Boden, William F. Crowley, Adrian G. Temnycky, Sally Radovick, Jeffrey Baron, Julian C. Lui, Youn Hee Jee, Jack A. Yanovski
Publikováno v:
Genetics in medicine : official journal of the American College of Medical Genetics
Purpose Impaired function of gonadotropin-releasing hormone (GnRH) neurons can cause a phenotypic spectrum ranging from delayed puberty to isolated hypogonadotropic hypogonadism (IHH). We sought to identify a new genetic etiology for these conditions
Autor:
Sehoon Won, Katherine W. Roche
Publikováno v:
The Journal of Physiology. 599:443-451
Phosphorylation regulates glutamate receptor trafficking. The cytosolic C-terminal domains of both NMDA receptors (NMDARs) and AMPA receptors (AMPARs) have distinct motifs, which are substrates for serine/threonine and tyrosine phosphorylation. Decad
Publikováno v:
Proceedings of the National Academy of Sciences. 116:8028-8037
Significance Striatal-enriched protein tyrosine phosphatase (STEP) regulates the trafficking and function of a variety of synaptic proteins, including receptors and protein kinases. In addition, STEP’s expression and activity are altered in many ne
Autor:
Sehoon, Won, Katherine W, Roche
Publikováno v:
The Journal of physiologyReferences. 599(2)
Phosphorylation regulates glutamate receptor trafficking. The cytosolic C-terminal domains of both NMDA receptors (NMDARs) and AMPA receptors (AMPARs) have distinct motifs, which are substrates for serine/threonine and tyrosine phosphorylation. Decad
Autor:
Sehoon Won, Katie S. Kindt, Catherine M. Drerup, Natalie Mosqueda, Alisha Beirl, Richa Madan Lomash, Katherine Pinter, Amrita Mandal
Mitochondrial transport in neurons is essential for forming and maintaining axonal projections. While much is known about anterograde mitochondrial movement, the function of retrograde mitochondrial motility in neurons was unknown. We investigated th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::552be9f7bb837651f24b80917da7823e
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 116(16)
Striatal-enriched protein tyrosine phosphatase (STEP) is a brain-specific protein phosphatase that regulates a variety of synaptic proteins, including NMDA receptors (NAMDRs). To better understand STEP’s effect on other receptors, we used mass spec
Publikováno v:
Current opinion in neurobiology. 43
The PSD-95 family of proteins, known as MAGUKs, have long been recognized to be central building blocks of the PSD. They are categorized as scaffolding proteins, which link surface-expressed receptors to the intracellular signaling molecules. Althoug
Publikováno v:
Proceedings of the National Academy of Sciences. 113
Phosphorylation regulates surface and synaptic expression of NMDA receptors (NMDARs). Both the tyrosine kinase Fyn and the tyrosine phosphatase striatal-enriched protein tyrosine phosphatase (STEP) are known to target the NMDA receptor subunit GluN2B