Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Sehime Gulsun Temel"'
Autor:
Gulten Tuncel, Burcin Sanlıdag, Eray Dirik, Tugba Baris, Mahmut Cerkez Ergoren, Sehime Gulsun Temel
Publikováno v:
Global Medical Genetics, Vol 10, Iss 03, Pp 240-246 (2023)
Spinal muscular atrophy (SMA) is a rare, recessively inherited neurodegenerative disorder caused by the presence of pathogenic variants in the SMN gene. As it is the leading inherited cause of infant mortality, identification of SMN gene pathogenic v
Externí odkaz:
https://doaj.org/article/d393add898a843b9b163c7108e2bbea4
Autor:
Ibrahim Boga, Sebnem Ozemri Sag, Nilgun Duman, Sevda Yesim Ozdemir, Mahmut Cerkez Ergoren, Kubilay Dalci, Cem Mujde, Cem Kaan Parsak, Cagla Rencuzogullari, Ozge Sonmezler, Orcun Yalav, Adem Alemdar, Lamiya Aliyeva, Ozlem Bozkurt, Sibel Cetintas, Erdem Cubukcu, Adem Deligonul, Berkcan Dogan, Cemre Ornek Erguzeloglu, Turkkan Evrensel, Sehsuvar Gokgoz, Kazim Senol, Sahsine Tolunay, Esra Akyurek, Neslihan Basgoz, Nuriye Gökçe, Bilge Dundar, Figen Ozturk, Duygu Taskin, Mercan Demirtas, Murat Cag, Omer Diker, Polat Olgun, Sevcan Tug Bozdogan, Munis Dundar, Atil Bisgin, Sehime Gulsun Temel
Publikováno v:
European Journal of Breast Health, Vol 19, Iss 3, Pp 235-252 (2023)
Objective:Breast cancer (BC) is the most common cancer type in women and may be inherited, mostly in an autosomal dominant pattern. The clinical diagnosis of BC relies on the published diagnostic criteria, and analysis of two genes, BRCA1 and BRCA2,
Externí odkaz:
https://doaj.org/article/a71c390801df4f9498bd73b6b92a7cb8
Autor:
Aya Badeea Ismail, Mehmet Sait Dundar, Cemre Ornek Erguzeloglu, Mahmut Cerkez Ergoren, Adem Alemdar, Sebnem Ozemri Sag, Sehime Gulsun Temel
Publikováno v:
Biomedicines, Vol 12, Iss 5, p 968 (2024)
Alzheimer’s disease (AD) is a major global health challenge, especially among individuals aged 65 or older. According to population health studies, Turkey has the highest AD prevalence in the Middle East and Europe. To accurately determine the freq
Externí odkaz:
https://doaj.org/article/911415175df84fada0540492352d7bd9
Autor:
Bahriye Karakas, Yeliz Aka, Asli Giray, Sehime Gulsun Temel, Ufuk Acikbas, Huveyda Basaga, Ozgur Gul, Ozgur Kutuk
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-14 (2021)
Abstract Breast cancer is the most common cancer with a high rate of mortality and morbidity among women worldwide. Estrogen receptor status is an important prognostic factor and endocrine therapy is the choice of first-line treatment in ER-positive
Externí odkaz:
https://doaj.org/article/44d45a0c3a7546519ca7435ae2928d1c
Autor:
Mahmut C. Ergoren, Erdal Eren, Elena Manara, Stefano Paolacci, Pinar Tulay, Sebnem O. Sag, Matteo Bertelli, Gamze Mocan, Sehime Gulsun Temel
Publikováno v:
Global Medical Genetics, Vol 08, Iss 03, Pp 100-103 (2021)
Achondroplasia (ACH) is a hereditary disorder of dwarfism that is caused by the aberrant proliferation and differentiation of chondrocyte growth plates. The common findings of macrocephaly and facial anomalies accompany dwarfism in these patients. Fi
Externí odkaz:
https://doaj.org/article/25af990199424ec8aeca1660290848e9
Publikováno v:
PeerJ, Vol 10, p e12947 (2022)
Background Impaired meiosis can result in absence of sperm in the seminal fluid. This condition, namely non-obstructive azoospermia (NOA), is one of the reasons of male infertility. Despite the low number of studies on meiosis 1-associated protein (M
Externí odkaz:
https://doaj.org/article/c4bd6d2670524b079ca282269267db82
Autor:
Niyazi Senturk, Gulten Tuncel, Berkcan Dogan, Lamiya Aliyeva, Mehmet Sait Dundar, Sebnem Ozemri Sag, Gamze Mocan, Sehime Gulsun Temel, Munis Dundar, Mahmut Cerkez Ergoren
Publikováno v:
Genes, Vol 12, Iss 11, p 1774 (2021)
Artificial intelligence provides modelling on machines by simulating the human brain using learning and decision-making abilities. Early diagnosis is highly effective in reducing mortality in cancer. This study aimed to combine cancer-associated risk
Externí odkaz:
https://doaj.org/article/34d3a02102d843b8aa3a735aa953a776
Autor:
Ozgur Kutuk, Nurgul Aytan, Bahriye Karakas, Asli Giray Kurt, Ufuk Acikbas, Sehime Gulsun Temel, Huveyda Basaga
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182809 (2017)
Necrosis, apoptosis and autophagic cell death are the main cell death pathways in multicellular organisms, all with distinct and overlapping cellular and biochemical features. DNA damage may trigger different types of cell death in cancer cells but t
Externí odkaz:
https://doaj.org/article/dd8aabf79cfe4db6b9fed0b38da53684
Autor:
Cagri Ogur, Semra Kahraman, Darren Karl Griffin, Cigdem Cinar Yapan, Mehmet Ali Tufekci, Murat Cetinkaya, Sehime Gulsun Temel, Alper Yilmaz
Publikováno v:
Reproductive BioMedicine Online. 46:713-727
Autor:
Sehime Gulsun Temel, Mahmut Cerkez Ergoren, Izel Yilmaz, Ozel Yuruker, Havva Cobanogullari, Ozgur Tosun, Haluk Barbaros Oral, Nerin Nadir Bahceciler
Publikováno v:
The EuroBiotech Journal. 6:126-132
Objective: Allergic asthma is the most frequently observed subtype of individuals with asthma. The effects of serotonin plays in the pathophysiology of asthma has not been clearly determined. Thus, this study aimed to investigate the association betw