Pharmacoinformatic and molecular docking studies reveal potential novel antidepressants against neurodegenerative disorders by targeting HSPB8

Autor: Sehgal SA, Mannan S, Ali S

Publikováno v: Drug Design, Development and Therapy, Vol 2016, Iss Issue 1, Pp 1605-1618 (2016)

Sheikh Arslan Sehgal,1–4 Shazia Mannan,1 Sannia Ali1 1Department of Bioscience, COMSATS Institute of Information Technology, Sahiwal, Pakistan; 2State Key Laboratory of Biomembrane and Membrane Biotechnology, Institute of Zoology, Chinese Academy o

Externí odkaz: https://doaj.org/article/e74640092bc84922b15e55b0de9e64f1

Pharmacoinformatics elucidation of potential drug targets against migraine to target ion channel protein KCNK18

Autor: Sehgal SA, Hassan M, Rashid S

Publikováno v: Drug Design, Development and Therapy, Vol 2014, Iss default, Pp 571-581 (2014)

Sheikh Arslan Sehgal, Mubashir Hassan, Sajid Rashid National Center for Bioinformatics, Quaid-i-Azam University, Islamabad, Pakistan Abstract: Migraine, a complex debilitating neurological disorder is strongly associated with potassium channel subfam

Externí odkaz: https://doaj.org/article/adbef12d416641d19217ba0ded6a4ceb

In silico designing of multiepitope-based-peptide (MBP) vaccine against MAPK protein express for Alzheimer's disease in Zebrafish.

Autor: Arfat Y; Department of Biotechnology, Faculty of Life Sciences, University of Okara, Okara, 56300, Pakistan., Zafar I; Department of Bioinformatics and Computational Biology, Virtual University, Punjab, 54700, Pakistan., Sehgal SA; Department of Bioinformatics, Institute of Biochemistry, Biotechnology and Bioinformatics, The Islamia University of Bahawalpur, Bahawalpur, Pakistan., Ayaz M; Department of Parasitology, Faculty of Veterinary Science, Cholistan University of Veterinary and Animal Sciences, Bahawalpur, Pakistan., Sajid M; Department of Biotechnology, Faculty of Life Sciences, University of Okara, Okara, 56300, Pakistan., Khan JM; Department of Parasitology, Faculty of Veterinary Science, Cholistan University of Veterinary and Animal Sciences, Bahawalpur, Pakistan., Ahsan M; Department of Environmental Sciences, Institute of Environmental and Agricultural Sciences, University of Okara, Okara, 56300, Pakistan., Rather MA; Division of Fish Genetics and Biotechnology, Faculty of Fisheries, Rangil- Gandarbal (SKAUST-K), India., Khan AA; Pharmaceutical Biotechnology Laboratory, Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh, 11451, Saudi Arabia., Alshehri JM; Pharmaceutical Biotechnology Laboratory, Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh, 11451, Saudi Arabia., Akash S; Department of Pharmacy, Faculty of Allied Health Sciences, Daffodil International, University, Dhaka, Bangladesh., Nepovimova E; Department of Chemistry, Faculty of Science, University of Hradec Králové, Hradec Králové, 50 003, Czech Republic., Kuca K; Department of Chemistry, Faculty of Science, University of Hradec Králové, Hradec Králové, 50 003, Czech Republic.; Biomedical Research Center, University Hospital Hradec Kralove, 50005, Hradec Kralove, Czech Republic., Sharma R; Department of Rasashastra and Bhaishajya Kalpana, Faculty of Ayurveda, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.

Publikováno v: Heliyon [Heliyon] 2023 Nov 12; Vol. 9 (11), pp. e22204. Date of Electronic Publication: 2023 Nov 12 (Print Publication: 2023).

Elucidation of novel compounds and epitope-based peptide vaccine design against C30 endopeptidase regions of SARS-CoV-2 using immunoinformatics approaches.

Autor: Marriam S; Department of Microbiology and Molecular Genetics, Faculty of Life Sciences, University of Okara, Okara, Pakistan., Afghan MS; Department of Ear, Nose, and Throat (ENT), District Headquarter (DHQ) Teaching Hospital Faisalabad, Faisalabad, Punjab, Pakistan., Nadeem M; Department of Ear, Nose, and Throat (ENT), District Headquarter (DHQ) Teaching Hospital Faisalabad, Faisalabad, Punjab, Pakistan., Sajid M; Department of Biotechnology, Faculty of Life Sciences, University of Okara, Okara, Pakistan., Ahsan M; Institute of Environmental and Agricultural Sciences, University of Okara, Okara, Pakistan., Basit A; Department of Microbiology, University of Jhang, Jhang, Pakistan., Wajid M; Department of Zoology, Faculty of Life Sciences, University of Okara, Okara, Pakistan., Sabri S; Department of Microbiology and Molecular Genetics, Faculty of Life Sciences, University of Okara, Okara, Pakistan., Sajid M; Department of Biotechnology, Faculty of Life Sciences, University of Okara, Okara, Pakistan., Zafar I; Department of Bioinformatics and Computational Biology, Virtual University, Punjab, Pakistan., Rashid S; Department of Pharmacology and Toxicology, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia., Sehgal SA; Department of Bioinformatics, Faculty of Life Sciences, University of Okara, Okara, Pakistan.; Department of Bioinformatics, Institute of Biochemistry, Biotechnology and Bioinformatics, The Islamia University of Bahawalpur, Bahawalpur, Pakistan., Alkhalifah DHM; Department of Biology, College of Science, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia., Hozzein WN; Botany and Microbiology Department, Faculty of Science, Beni-Suef University, Beni-Suef, Egypt., Chen KT; Department of Occupational Medicine, Tainan Municipal Hospital (managed by ShowChwan Medical Care Corporation), Tainan, Taiwan.; Department of Public Health, College of Medicine, National Cheng Kung University, Tainan, Taiwan., Sharma R; Department of Rasa Shastra and Bhaishajya Kalpana, Faculty of Ayurveda, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.

Publikováno v: Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2023 May 24; Vol. 13, pp. 1134802. Date of Electronic Publication: 2023 May 24 (Print Publication: 2023).

In silico elucidation of potential drug targets against oxygenase domain of Human eNOS Dysfunction.

Autor: Malik A; Department of Bioinformatics, Institute of Biochemistry, Biotechnology and Bioinformatics, The Islamia University of Bahawalpur, Bahawalpur, Pakistan., Iqbal MN; Department of Bioinformatics, Institute of Biochemistry, Biotechnology and Bioinformatics, The Islamia University of Bahawalpur, Bahawalpur, Pakistan., Ashraf S; Khawaja Muhammad Safdar Medical College Sialkot, Sialkot, Pakistan., Khan MS; Faculty of Lifesciences, Department of Zoology, University of Okara, Okara, Pakistan., Shahzadi S; Department of Bioinformatics, Institute of Biochemistry, Biotechnology and Bioinformatics, The Islamia University of Bahawalpur, Bahawalpur, Pakistan., Shafique MF; Department of Bioinformatics, Institute of Biochemistry, Biotechnology and Bioinformatics, The Islamia University of Bahawalpur, Bahawalpur, Pakistan., Sajid Z; Department of Biotechnology, Institute of Biochemistry, Biotechnology and Bioinformatics, The Islamia University of Bahawalpur, Bahawalpur, Pakistan., Sajid M; Department of Biotechnology, University of Okara, Okara, Pakistan., Sehgal SA; Department of Bioinformatics, Institute of Biochemistry, Biotechnology and Bioinformatics, The Islamia University of Bahawalpur, Bahawalpur, Pakistan.; Department of Bioinformatics, University of Okara, Okara, Pakistan.

Publikováno v: PloS one [PLoS One] 2023 Apr 26; Vol. 18 (4), pp. e0284993. Date of Electronic Publication: 2023 Apr 26 (Print Publication: 2023).