Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Seher Yuksel"'
Autor:
Yeshumenesh Zegeye, Bogale Aredo, Seher Yuksel, Dogan Can Kirman, Ashwani Kumar, Bo Chen, Emily Turpin, Sangita Shresta, Yu-Guang He, Laurent Gautron, Miao Tang, Xiaohong Li, Sophia M. DiCesare, John D. Hulleman, Chao Xing, Sara Ludwig, Eva Marie Y. Moresco, Bruce A. Beutler, Rafael L. Ufret-Vincenty
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Activated microglia have been implicated in the pathogenesis of age-related macular degeneration (AMD), diabetic retinopathy, and other neurodegenerative and neuroinflammatory disorders, but our understanding of the mechanisms behind their a
Externí odkaz:
https://doaj.org/article/9429c796dd824374af717a5bef932a51
Autor:
Seher Yuksel, Bogale Aredo, Yeshumenesh Zegeye, Cynthia X. Zhao, Miao Tang, Xiaohong Li, John D. Hulleman, Laurent Gautron, Sara Ludwig, Eva M. Y. Moresco, Igor A. Butovich, Bruce A. Beutler, Rafael L. Ufret-Vincenty
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-19 (2023)
Abstract Microglia play a role in the pathogenesis of many retinal diseases. Fundus spots in mice often correlate with the accumulation of activated subretinal microglia. Here we use a semiquantitative fundus spot scoring scale in combination with an
Externí odkaz:
https://doaj.org/article/3683c57a77574449a41c1f5040bcfed1
Autor:
Ozlem Ozkaya Akagunduz, Demet Etit, Gozde Yazici, Ali Veral, Oguz Cetinayak, Sulen Sarioglu, Gaye Guler Tezel, Sumerya Duru Birgi, Seher Yuksel, Gulsen Kara, Teuta Zoto Mustafayev, Fatma Tokat, Beyhan Ceylaner Bicakli, Kayhan Basak, Mustafa Esassolak, Fadime Akman, Enis Ozyar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e1efcd042a18af907d451c3426cd00c
https://avesis.deu.edu.tr/publication/details/7cc85ede-4b6b-478e-87ba-f85d2291bac7/oai
https://avesis.deu.edu.tr/publication/details/7cc85ede-4b6b-478e-87ba-f85d2291bac7/oai
Publikováno v:
J Biol Chem
Exocrine meibomian glands (MGs) play a central role in the ocular physiology and biochemistry by producing in situ and, mostly, de novo a secretion (meibum), which is composed of a complex mixture of homologous lipids of various classes, in a metabol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a79f8a042ebda31cce615575c8996d4
https://europepmc.org/articles/PMC10070659/
https://europepmc.org/articles/PMC10070659/
Autor:
Igor A. Butovich, Amber Wilkerson, Kelli R. Goggans, Olga V. Belyaeva, Natalia Y. Kedishvili, Seher Yuksel
Publikováno v:
Journal of Biological Chemistry. 299:104725
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b70fecfb9a15cbe749a1da4da174ef9a
https://doi.org/10.1016/j.jbc.2023.104725
https://doi.org/10.1016/j.jbc.2023.104725
Autor:
Daniel M. Albert, Arthur S. Polans, Brian C. Leonard, Igor A. Butovich, Tom Gadek, Seher Yuksel
Publikováno v:
J Ocul Pharmacol Ther
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, vol 37, iss 10
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, vol 37, iss 10
Purpose: Instability of the tear film leads to evaporative dry eye disease (EDED), but the Harderian gland in some terrestrial vertebrates may produce novel lipids that stabilize the tear film and protect against dry eye. Here, the nonpolar lipids in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d03861686f806a74a4579eb5c9f875ac
https://europepmc.org/articles/PMC8713569/
https://europepmc.org/articles/PMC8713569/
Autor:
Guldane Cengiz Seval, Isınsu Kuzu, Seher Yuksel, Hulya Yılmaz, Gul Yavuz, Gulsah Kaygusuz, Klara Dalva, Muhit Ozcan, Meral Beksac
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 22:S89-S90
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09746916cff7980833b1951327607461
https://doi.org/10.1016/s2152-2650(22)00429-3
https://doi.org/10.1016/s2152-2650(22)00429-3
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 1583, p 1583 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 4
International Journal of Molecular Sciences
Volume 22
Issue 4
Previous studies on ablation of several key genes of meibogenesis related to fatty acid elongation, omega oxidation, and esterification into wax esters have demonstrated that inactivation of any of them led to predicted changes in the meibum lipid pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9085b77bf7f0928b12a12c4ad2a8d062
https://www.mdpi.com/1422-0067/22/4/1583
https://www.mdpi.com/1422-0067/22/4/1583
Publikováno v:
FASEB J
Recently, elongase of very long chain fatty acids-3 (ELOVL3) was demonstrated to play a pivotal role in physiology and biochemistry of the ocular surface by maintaining a proper balance in the lipid composition of meibum. The goal of this study was t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c897bdd70499d2edd8ff524ad8e1344
https://doi.org/10.1096/fj.202002323r
https://doi.org/10.1096/fj.202002323r
Publikováno v:
J Steroid Biochem Mol Biol
Exocrine Meibomian glands (MG) play a central role in the ocular surface physiology by producing meibum – a lipid secretion composed of cholesteryl esters (CE), cholesterol (Chl), triacylgycerols (TAG), waxes and other types of lipids. MG were prev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b6480ed4f809061888d1066e87fc452
https://pubmed.ncbi.nlm.nih.gov/33819631
https://pubmed.ncbi.nlm.nih.gov/33819631