Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Seham A Abdel-Gaber"'
Publikováno v:
Asian Pacific Journal of Tropical Medicine, Vol 16, Iss 8, Pp 337-346 (2023)
Objective: To explore the clinical features, diagnosis, etiology, treatment, and outcomes of COVID-19 related empyema. Methods: Using PRISMA statement, a systematic search of relevant case reports published between December 2019 and April 2023 was pe
Externí odkaz:
https://doaj.org/article/1996bbc9d1c941169ee4256429e154be
Autor:
Mohamed A. Morsy, Seham A. Abdel-Gaber, Sahar A. Mokhemer, Mahmoud Kandeel, Wael F. Sedik, Anroop B. Nair, Katharigatta N. Venugopala, Hany Ezzat Khalil, Bandar E. Al-Dhubiab, Mervat Z. Mohamed
Publikováno v:
Pharmaceuticals, Vol 16, Iss 5, p 665 (2023)
The clinical usefulness of doxorubicin (DOX) is limited by its serious adverse effects, such as cardiotoxicity. Pregnenolone demonstrated both anti-inflammatory and antioxidant activity in animal models. The current study aimed to investigate the car
Externí odkaz:
https://doaj.org/article/9fa69729efb9480dbde210f6f11d1777
Autor:
Mohamed A. Morsy, Azza A. K. El-Sheikh, Sara Mohamed Naguib Abdel-Hafez, Mahmoud Kandeel, Seham A. Abdel-Gaber
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Methotrexate (MTX) is a well-known anticancer drug that causes nephrotoxicity as a side effect. To investigate the mechanisms by which paeonol, a natural phenolic compound, can protect against MTX-induced nephrotoxicity, paeonol (100 mg/kg/day orally
Externí odkaz:
https://doaj.org/article/9ef02b36627b40468cb445f5de0a4dfa
Autor:
Mohamed A. Morsy, Mahmoud Kandeel, Ahmed R. N. Ibrahim, Seham A. Abdel-Gaber, Shery Jacob, Katharigatta N. Venugopala, Pottathil Shinu, Mahmoud El-Daly
Publikováno v:
Molecules, Vol 27, Iss 21, p 7383 (2022)
The activity of the P-glycoprotein (P-gp) transporter encoded by the ABCB1 gene confers resistance to anticancer drugs and contributes to cancer-related mortality and morbidity. Recent studies revealed the cytotoxic effects of the endogenous dipeptid
Externí odkaz:
https://doaj.org/article/6bab9bd3c7474cc4b2c6d7baadfa7580
Autor:
Mohamed A. Morsy, Rania Abdel-Latif, Sara Mohamed Naguib Abdel Hafez, Mahmoud Kandeel, Seham A. Abdel-Gaber
Publikováno v:
Pharmaceuticals, Vol 15, Iss 10, p 1296 (2022)
Methotrexate (MTX) is an effective chemotherapeutic agent against a wide range of tumors and autoimmune diseases; however, hepatotoxicity limits its clinical use. Oxidative stress and inflammation have been implicated in the pathogenesis of MTX-induc
Externí odkaz:
https://doaj.org/article/5668148120324b16b6a3bcfd70331129
Autor:
Mohamed A. Morsy, Yasmine F. Ibrahim, Sara Mohamed Naguib Abdel Hafez, Nagwa M. Zenhom, Anroop B. Nair, Katharigatta N. Venugopala, Pottathil Shinu, Seham A. Abdel-Gaber
Publikováno v:
Antioxidants, Vol 11, Iss 9, p 1687 (2022)
Hepatic ischemia/reperfusion (HIR) is the most common type of liver injury following several clinical situations. Modulating oxidative stress and inflammation by Nrf2/HO-1 and TLR4/MYD88/NF-κB pathways, respectively, is involved in alleviating HIR i
Externí odkaz:
https://doaj.org/article/8492d4e6d42247729765effc2d52966f
Autor:
Abdulla Y. Al-Taher, Mohamed A. Morsy, Rehab A. Rifaai, Nagwa M. Zenhom, Seham A. Abdel-Gaber
Publikováno v:
Mediators of Inflammation, Vol 2020 (2020)
Methotrexate (MTX) is a commonly used chemotherapeutic agent. Oxidative stress and inflammation have been proved in the development of MTX toxicity. Paeonol is a natural phenolic compound with various pharmacological activities including antioxidant
Externí odkaz:
https://doaj.org/article/edcd63258e654c148478155fe2ac0627
Autor:
Mohamed A Ibrahim, Alyaa Abdelfattah Abdelmonaem, Seham A Abdel-Gaber, Heba M Hafez, Sara Mohamed Naguib Abdel Hafez, Walaa Yehia Abdelzaher
Publikováno v:
Journal of Pharmacy and Pharmacology. 74:537-546
Objectives This study aimed to analyse the potential effect of rupatadine (RUP) on ulcerative colitis (UC) induced by acetic acid (AA). Methods Forty male adult Wistar rats were divided into five groups: Control group: received vehicles for 14 days;
Autor:
Mohamed A. Morsy, Asmaa M. Abdel-Aziz, Sara M. N. Abdel-Hafez, Katharigatta N. Venugopala, Anroop B. Nair, Seham A. Abdel-Gaber
Publikováno v:
Pharmaceuticals, Vol 13, Iss 9, p 223 (2020)
Paeonol, a phenolic ingredient in the genus Paeonia, possesses antioxidant and anti-inflammatory effects. Methotrexate (MTX) is a commonly used chemotherapeutic agent; however, its germ cell damage is a critical problem. P-glycoprotein (P-gp), an eff
Externí odkaz:
https://doaj.org/article/e8af32c913dc4d2f858a8e76aec97e20
Autor:
Randa Ahmed Ibrahim, Sayed Shehata, Marwa M.M. Refaie, Seham A. Abdel-Gaber, Asmaa M A Bayoumi
Publikováno v:
Cardiovascular Toxicology. 21:1033-1044
Doxorubicin (DOX) is one of the most widely used chemotherapeutic drugs, but its cardiotoxicity has been shown to be a dose-restricting factor during therapy. Finding new agents for reducing these complications is still in critical need. The current