Zobrazeno 1 - 10 of 25 pro vyhledávání: '"Seh Hyon Song"'
1
Akademický článek
Tricaprylin‐based drug crystalline suspension for intramuscular long‐acting delivery of entecavir with alleviated local inflammation
Autor: Min Young Jeong, Myoung Jin Ho, Joon Soo Park, Hoetaek Jeong, Jin Hee Kim, Yong Jin Jang, Doe Myung Shin, In Gyu Yang, Hye Rim Kim, Woo Heon Song, Sangkil Lee, Seh Hyon Song, Yong Seok Choi, Young Taek Han, Myung Joo Kang
Publikováno v: Bioengineering & Translational Medicine, Vol 9, Iss 4, Pp n/a-n/a (2024)
Abstract In order to ensure prolonged pharmacokinetic profile along with local tolerability at the injection site, tricaprylin‐based drug crystalline suspension (TS) was designed and its local distribution, pharmacokinetics, and inflammatory respon
Externí odkaz: https://doaj.org/article/da7fadc36f0840148e50a7f1735aa509
Zobrazit plný text záznamu
2
Akademický článek
Enhanced oral absorption of insulin: hydrophobic ion pairing and a self-microemulsifying drug delivery system using a D-optimal mixture design
Autor: Yoon Tae Goo, Sangkil Lee, Ji Yeh Choi, Min Song Kim, Gi Hyeong Sin, Sun Ho Hong, Chang Hyun Kim, Seh Hyon Song, Young Wook Choi
Publikováno v: Drug Delivery, Vol 29, Iss 1, Pp 2831-2845 (2022)
The lipophilicity of a peptide drug can be considerably increased by hydrophobic ion pairing with amphiphilic counterions for successful incorporation into lipid-based formulations. Herein, to enhance the oral absorption of insulin (INS), a self-micr
Externí odkaz: https://doaj.org/article/7f248a6afc39449aa2b08ca02e12c71a
Zobrazit plný text záznamu
3
Akademický článek
Improved Dissolution and Oral Bioavailability of Valsartan Using a Solidified Supersaturable Self-Microemulsifying Drug Delivery System Containing Gelucire® 44/14
Autor: Dong Jun Shin, Bo Ram Chae, Yoon Tae Goo, Ho Yub Yoon, Chang Hyun Kim, Se Il Sohn, Dongho Oh, Ahram Lee, Seh Hyon Song, Young Wook Choi
Publikováno v: Pharmaceutics, Vol 11, Iss 2, p 58 (2019)
To improve the dissolution and oral bioavailability of valsartan (VST), we previously formulated a supersaturable self-microemulsifying drug delivery system (SuSMED) composed of Capmul® MCM (oil), Tween® 80 (surfactant), Transcutol® P (cosurfactan
Externí odkaz: https://doaj.org/article/48d94e0b9c8c45dc980aa388b7c81cb8
Zobrazit plný text záznamu
4
Akademický článek
Evaluation of the Efficacy of an Elastin-Inducing Composition Containing Amino Acids, Copper, and Hyaluronic Acid: Results of an Open Single-Center Clinical Trial Study
Autor: Man-Seok Kim, Ko-Eun Chun, Dong-Keun Lee, Seh-Hyon Song
Publikováno v: Cosmetics, Vol 9, Iss 3, p 51 (2022)
The degradation and reduction in number of extracellular matrix (ECM) proteins are representative biological changes associated with decreased elasticity resulting in various skin problems. Elastin is an ECM protein that plays an important role in ma
Externí odkaz: https://doaj.org/article/aee19ec5a19c4ca1b2f9cf9a7c96cc28
Zobrazit plný text záznamu
7
Supersaturable self-microemulsifying drug delivery system enhances dissolution and bioavailability of telmisartan
Autor: Sang Beom Han, Ho Yub Yoon, Bo Ram Chae, Seh Hyon Song, Sun Young Park, Chang Hyun Kim, Yoon Tae Goo, Chang Hwa Jin, Young Wook Choi
Publikováno v: Pharmaceutical Development and Technology. 26:60-68
To enhance the dissolution and oral bioavailability of telmisartan (TMS), a poorly water-soluble anti-hypertensive drug, a supersaturable self-microemulsifying drug delivery system (SuSMEDDS) was developed. Amorphous alkalinized TMS (AAT) was formula
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e74d7c28dc1d1d145630018e95f7264a
https://doi.org/10.1080/10837450.2020.1834580
Zobrazit plný text záznamu
8
Enhanced oral bioavailability of valsartan in rats using a supersaturable self-microemulsifying drug delivery system with P-glycoprotein inhibitors
Autor: Young Wook Choi, Bo Ram Chae, Chang Hyun Kim, Tae Hoon Kang, Sun Young Park, Sangkil Lee, Seh Hyon Song, Yoon Tae Goo, Ho Yub Yoon, Dong Woo Yeom
Publikováno v: Pharmaceutical Development and Technology. 25:178-186
Valsartan (VST) is a poorly water-soluble drug and a P-glycoprotein (P-gp) substrate. To enhance the dissolution and oral absorption of VST, a novel supersaturable self-microemulsifying drug delivery system (Su-SMEDDS) was formulated. Based on the pr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5680fa145250698a5902af79c689160
https://doi.org/10.1080/10837450.2019.1683749
Zobrazit plný text záznamu
9
Intravesical delivery of rapamycin via folate-modified liposomes dispersed in thermo-reversible hydrogel
Autor: Young Mi Whang, Chang Hyun Kim, In Ho Chang, Ho Yub Yoon, Soo-Yeon Kim, Yoon Tae Goo, Seh Hyon Song, Tae Hoon Kang, Sang Jin Lee, Young-Wook Choi
Publikováno v: International Journal of Nanomedicine. 14:6249-6268
Purpose To develop an intravesical instillation system for the treatment of bladder cancer, rapamycin (Rap) was encapsulated into liposomes and then homogeneously dispersed throughout a poloxamer 407 (P407)-based hydrogel. Methods Rap-loaded conventi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::645d65a3fec416406159a58d39d2ba52
https://doi.org/10.2147/ijn.s216432
Zobrazit plný text záznamu
10
Synergistic effect of copper and amino acid mixtures on the production of extracellular matrix proteins in skin fibroblasts
Autor: Seh Hyon Song, Ki Wung Chung, Man-Seok Kim
Publikováno v: Molecular biology reports. 48(4)
The stimulation of extracellular matrix (ECM) protein production is an interesting target to maintain normal skin structure and delay skin aging. Copper has been shown to stimulate ECM protein synthesis by activating lysyl oxidase. Although copper in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb355763c5cf4b6c7c701cedb682c6bf
https://pubmed.ncbi.nlm.nih.gov/34009566
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje