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Epigenomic and Transcriptomic Profiling of Solitary Fibrous Tumors Identifies Site-Specific Patterns and Candidate Genes Regulated by DNA Methylation.

Autor: Beird HC; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Cloutier JM; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Gokgoz N; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital Toronto, Ontario, Canada., Eeles C; Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada., Griffin AM; University of Toronto Musculoskeletal Oncology Unit, Division of Orthopaedic Surgery, Department of Surgery, Mount Sinai Hospital, Toronto, Ontario, Canada., Ingram DR; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Wani KM; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Segura RL; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Cohen L; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Ho C; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Wunder JS; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital Toronto, Ontario, Canada; University of Toronto Musculoskeletal Oncology Unit, Division of Orthopaedic Surgery, Department of Surgery, Mount Sinai Hospital, Toronto, Ontario, Canada., Andrulis IL; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital Toronto, Ontario, Canada; Department of Molecular Genetics Canada, University of Toronto, Toronto, Ontario, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada., Futreal PA; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Haibe-Kains B; Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada; Vector Institute for Artificial Intelligence, Toronto, Ontario, Canada., Lazar AJ; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Wang WL; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Przybyl J; Department of Surgery, McGill University & Cancer Research Program, The Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada., Demicco EG; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada; Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, Ontario, Canada. Electronic address: Elizabeth.demicco@sinaihealth.ca.

Publikováno v: Laboratory investigation; a journal of technical methods and pathology [Lab Invest] 2024 Nov; Vol. 104 (11), pp. 102146. Date of Electronic Publication: 2024 Sep 30.