APOA2 increases cholesterol efflux capacity to plasma HDL by displacing the C-terminus of resident APOA1.

Autor: Sarkar S; Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA, USA., Morris J; Department of Pathology and Laboratory Medicine, University of Cincinnati, Cincinnati, OH, USA., You Y; Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA, USA., Sexmith H; Department of Pediatrics, Cincinnati Children's Hospital Medical Center and the University of Cincinnati, Cincinnati, OH, USA., Street SE; Department of Pathology and Laboratory Medicine, University of Cincinnati, Cincinnati, OH, USA., Thibert SM; Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland, WA, USA., Attah IK; Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA, USA., Hutchinson Bunch CM; Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA, USA., Novikova IV; Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland, WA, USA., Evans JE; Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland, WA, USA., Shah AS; Department of Pediatrics, Cincinnati Children's Hospital Medical Center and the University of Cincinnati, Cincinnati, OH, USA., Gordon SM; Department of Physiology and the Saha Cardiovascular Research Center, University of Kentucky College of Medicine, Lexington, KY, USA., Segrest JP; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Bornfeldt KE; Department of Medicine, UW Medicine Diabetes Institute, University of Washington, Seattle WA, USA., Vaisar T; Department of Medicine, UW Medicine Diabetes Institute, University of Washington, Seattle WA, USA., Heinecke JW; Department of Medicine, UW Medicine Diabetes Institute, University of Washington, Seattle WA, USA., Davidson WS; Department of Pathology and Laboratory Medicine, University of Cincinnati, Cincinnati, OH, USA. Electronic address: sean.davidson@uc.edu., Melchior JT; Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA, USA; Department of Pathology and Laboratory Medicine, University of Cincinnati, Cincinnati, OH, USA; Department of Neurology, Oregon Health and Science University, Portland, OR, USA. Electronic address: john.melchior@pnnl.gov.

Publikováno v: Journal of lipid research [J Lipid Res] 2024 Dec; Vol. 65 (12), pp. 100686. Date of Electronic Publication: 2024 Oct 28.

Flipped C-Terminal Ends of APOA1 Promote ABCA1-dependent Cholesterol Efflux by Small HDLs.

Autor: He Y; Department of Medicine, University of Washington, Seattle, WA, 98109, USA., Pavanello C; Centro Grossi Paoletti, Dipartimento di Scienze Farmacologiche e Biomolecolari, Università degli Studi di Milano, Milano, Italy., Hutchins PM; Department of Medicine, University of Washington, Seattle, WA, 98109, USA., Tang C; Department of Medicine, University of Washington, Seattle, WA, 98109, USA., Pourmousa M; Laboratory of Computational Biology, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892., Vaisar T; Department of Medicine, University of Washington, Seattle, WA, 98109, USA., Song HD; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, 37240, USA., Pastor RW; Laboratory of Computational Biology, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892., Remaley AT; Department of Laboratory Medicine, National Institutes of Health, Bethesda, MD 20892., Goldberg IJ; Department of Medicine, New York University, New York, NY, 10016, USA., Costacou T; Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA, 15261, USA., Davidson WS; Department of Pathology and Laboratory Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, 45237, USA., Bornfeldt KE; Department of Medicine, University of Washington, Seattle, WA, 98109, USA., Calabresi L; Centro Grossi Paoletti, Dipartimento di Scienze Farmacologiche e Biomolecolari, Università degli Studi di Milano, Milano, Italy., Segrest JP; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, 37240, USA., Heinecke JW; Department of Medicine, University of Washington, Seattle, WA, 98109, USA.

Publikováno v: MedRxiv : the preprint server for health sciences [medRxiv] 2023 Nov 04. Date of Electronic Publication: 2023 Nov 04.

Specialized Cellular Domains for ABCA1-mediated Cholesterol Efflux Detected by Quantitative Electron Microscopy.

Autor: Jerome WGJ; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA., Hart RC; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA., Aller SG; Department of Pharmacology & Toxicology, University of Alabama at Birmingham, Birmingham, AL, USA., Tang C; Department of Medicine, University of Washington, Seattle, WA, USA., Heinecke JW; Department of Medicine, University of Washington, Seattle, WA, USA., Davidson WS; Department of Pathology and Laboratory Medicine, University of Cincinnati, Cincinnati, OH, USA., Segrest JP; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.

Publikováno v: Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada [Microsc Microanal] 2023 Jul 22; Vol. 29 (29 Suppl 1), pp. 1096-1097.

Conformational flexibility of apolipoprotein A-I amino- and carboxy-termini is necessary for lipid binding but not cholesterol efflux.

Autor: Bedi S; Department of Pathology and Laboratory Medicine, University of Cincinnati, Cincinnati, OH, USA., Morris J; Department of Pathology and Laboratory Medicine, University of Cincinnati, Cincinnati, OH, USA., Shah A; Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA., Hart RC; Department of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, TN, USA., Jerome WG; Department of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, TN, USA., Aller SG; Department of Pharmacology and Toxicology, University of Alabama at Birmingham, Birmingham, AL, USA., Tang C; Department of Medicine, University of Washington School of Medicine, Seattle, WA, USA., Vaisar T; Department of Medicine, University of Washington School of Medicine, Seattle, WA, USA., Bornfeldt KE; Department of Medicine, University of Washington School of Medicine, Seattle, WA, USA., Segrest JP; Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA., Heinecke JW; Department of Medicine, University of Washington School of Medicine, Seattle, WA, USA., Davidson WS; Department of Pathology and Laboratory Medicine, University of Cincinnati, Cincinnati, OH, USA. Electronic address: Sean.Davidson@UC.edu.

Publikováno v: Journal of lipid research [J Lipid Res] 2022 Mar; Vol. 63 (3), pp. 100168. Date of Electronic Publication: 2022 Jan 17.

Prevalence and Association of Components of Metabolic Syndrome and Uric Acid among Commercial Drivers in South-West Nigeria.

Autor: Ajayi, David D.¹ (AUTHOR), Raimi, Taiwo H.² (AUTHOR) taiwo.raimi@eksu.edu.ng, Dada, Samuel A.² (AUTHOR)

Publikováno v: Annals of African Medicine. Jan-Mar2025, Vol. 24 Issue 1, p152-160. 9p.