Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Seetharama D. Satyanarayanajois"'
Autor:
Lina H. K. Lim, Seetharama D. Satyanarayanajois, Sakshi Sikka, Brad G. Stiles, Sulaiman Ali Alharbi, Arunachalam Chinnathambi, Kodappully Sivaraman Siveen, M. E. Zayed, Ramar Perumal Samy, Gautam Sethi, Alan Prem Kumar, Maung Maung Thwin
Publikováno v:
Biochimie. 111:30-44
Antimicrobial peptides (AMPs) play a vital role in defense against resistant bacteria. In this study, eight different AMPs synthesized from Python reticulatus serum protein were tested for bactericidal activity against various Gram-positive and Gram-
Publikováno v:
Immunotherapy. 6:755-774
Peptides and peptidomimetics can function as immunomodulating agents by either blocking the immune response or stimulating the immune response to generate tolerance. Knowledge of B- or T-cell epitopes along with conformational constraints is importan
Publikováno v:
Biopolymers. 101:693-702
Human epidermal growth factor receptor-2 (HER2) is a tyrosine kinase family protein receptor that is known to undergo heterodimerization with other members of the family of epidermal growth factor receptors (EGFR) for cell signaling. Overexpression o
Autor:
Alecia McCall, Sashikanth Banappagari, Krystal R. Fontenot, M. Graça H. Vicente, Seetharama D. Satyanarayanajois, Amit D. Gujar
Publikováno v:
European Journal of Medicinal Chemistry. 65:60-69
Among the EGFRs, HER2 is a major heterodimer partner and also has important implications in the formation of particular tumors. Interaction of HER2 protein with other EGFR proteins can be modulated by small molecule ligands and, hence, these protein-
Autor:
Vincent T. K. Chow, Bradley G. Stiles, Seetharama D. Satyanarayanajois, Ramar Perumal Samy, Ponnampalam Gopalakrishnakone
Publikováno v:
Current Proteomics. 10:10-28
Autor:
Paul W. Sylvester, Alaadin Alayoubi, Seetharama D. Satyanarayanajois, Shanthi Kanthala, John F. Anderson, Sami Nazzal
Publikováno v:
Colloids and Surfaces B: Biointerfaces. 103:23-30
The objectives of this work were to engineer physically stable "Vitamin E" rich intravenous lipid emulsions and to evaluate their in vitro antiproliferative activity against MCF-7 (human mammary adenocarcinoma) and SW-620 (human colon adenocarcinoma)
Autor:
Alaadin Alayoubi, John F. Anderson, Sami Nazzal, Seetharama D. Satyanarayanajois, Paul W. Sylvester
Publikováno v:
European Journal of Pharmaceutical Sciences. 48:385-392
Tocotrienol rich fraction (TRF) of vitamin E was previously shown to have anticancer activity against murine tumor cells in vitro. TRF was also shown to potentiate the anticancer activity of statins. The objectives of this study were therefore (a) to
Autor:
Sami Nazzal, Paul W. Sylvester, Alaadin Alayoubi, Seetharama D. Satyanarayanajois, Ahmed Abu Fayyad, Mohammad M. Kamal, John F. Anderson
Publikováno v:
2016 32nd Southern Biomedical Engineering Conference (SBEC).
Among two groups of components of Vitamine E, tocopherols and tocotrienols (T3), T3 shown to have anticancer property. It has been also reported that T3 potentiate the anticancer activity of some other drugs including statins when delivered simultane
Publikováno v:
Future Medicinal Chemistry. 3:1765-1786
Rapid advances in our collective understanding of biomolecular structure and, in concert, of biochemical systems, coupled with developments in computational methods, have massively impacted the field of medicinal chemistry over the past two decades,
Publikováno v:
Journal of Medicinal Chemistry. 54:5307-5319
Cell adhesion molecule CD2 and its ligand CD58 provide good examples of protein-protein interactions in cells that participate in the immune response. To modulate the cell adhesion interaction, peptides were designed from the discontinuous epitopes o