Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Seetharama, Jois"'
Autor:
Achyut Dahal, Pravin Parajuli, Sitanshu S. Singh, Leeza Shrestha, Jafrin Jobayer Sonju, Prajesh Shrestha, Ioulia Chatzistamou, Seetharama Jois
Publikováno v:
Journal of Pharmacological Sciences, Vol 149, Iss 3, Pp 124-138 (2022)
Protein–protein interactions (PPI) of co-stimulatory molecules CD2-CD58 are important in the early stage of an immune response, and increased expression of these co-stimulatory molecules is observed in the synovial region of joints in rheumatoid ar
Externí odkaz:
https://doaj.org/article/6f4a099918274d28861606dab32d7cbf
Publikováno v:
Clinical and Translational Discovery, Vol 2, Iss 3, Pp n/a-n/a (2022)
Externí odkaz:
https://doaj.org/article/d067cab6c02d4fea88a0968ff56da7a6
Autor:
Uddin, Mohammad A., Kubra, Khadeja-Tul, Sonju, Jafrin Jobayer, Akhter, Mohammad S., Seetharama, Jois, Barabutis, Nektarios
Publikováno v:
In Medicine in Drug Discovery June 2020 6
Autor:
Therese Marie A. Collantes, Carolyn M. Clark, Farhana Musarrat, Nithya Jambunathan, Seetharama Jois, Konstantin G. Kousoulas
Publikováno v:
Viruses, Vol 14, Iss 10, p 2189 (2022)
The alphaherpesvirus UL37 tegument protein is a highly conserved, multi-functional protein. Mutagenesis analysis delineated the UL37 domains necessary for retrograde transport and viral replication. Specifically, the amino-terminal 480 amino acids ar
Externí odkaz:
https://doaj.org/article/0655d2a6c14a4572a1646515c56e019b
Autor:
Rushikesh Sable, Nithya Jambunathan, Sitanshu Singh, Sandeep Pallerla, Konstantin G Kousoulas, Seetharama Jois
Publikováno v:
BioTechniques, Vol 65, Iss 3, Pp 149-157 (2018)
Protein–protein interactions (PPI) by homo-, hetero- or oligo-merization in the cellular environment regulate cellular processes. PPI can be inhibited by antibodies, small molecules or peptides, and this inhibition has therapeutic value. A recently
Externí odkaz:
https://doaj.org/article/3ed450dac3884a9993c31e64ffbd547e
Publikováno v:
Clinical and translational discovery. 2(3)
Autor:
Himgauri Naik, Jafrin Jobayer Sonju, Sitanshu Singh, Ioulia Chatzistamou, Leeza Shrestha, Ted Gauthier, Seetharama Jois
Publikováno v:
Pharmaceuticals, Vol 14, Iss 3, p 221 (2021)
The therapeutic index of chemotherapeutic agents can be improved by the use of nano-carrier-mediated chemotherapeutic delivery. Ligand-targeted drug delivery can be used to achieve selective and specific delivery of chemotherapeutic agents to cancer
Externí odkaz:
https://doaj.org/article/01d511eee117468aa06699ba43545a3e
Autor:
Rushikesh Sable, Seetharama Jois
Publikováno v:
Molecules, Vol 20, Iss 6, Pp 11569-11603 (2015)
Blocking protein-protein interactions (PPI) using small molecules or peptides modulates biochemical pathways and has therapeutic significance. PPI inhibition for designing drug-like molecules is a new area that has been explored extensively during th
Externí odkaz:
https://doaj.org/article/5dfca8faddfb4f8a84d45fef30ac9264
Autor:
Achyut Dahal, Pravin Parajuli, Sitanshu S. Singh, Leeza Shrestha, Jafrin Jobayer Sonju, Prajesh Shrestha, Ioulia Chatzistamou, Seetharama Jois
Publikováno v:
Journal of pharmacological sciences. 149(3)
Protein-protein interactions (PPI) of co-stimulatory molecules CD2-CD58 are important in the early stage of an immune response, and increased expression of these co-stimulatory molecules is observed in the synovial region of joints in rheumatoid arth
Publikováno v:
The Journal of Peptide Research. 49:15-22
A 10 amino acid residue cyclic peptide, cyclo(2,9)-Ac-Glnl-Cys2-Arg3-Ser4-Val5-Glu6-Gly7-Ser8-Cys9-Glyl0, from the C-terminal region of human growth hormone (hGH) was synthesized and studied by 2D proton NMR and molecular dynamics (MD) simulations. T