Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Seetha Srinivasan"'
Publikováno v:
Cell Reports, Vol 3, Iss 5, Pp 1629-1639 (2013)
SUMMARY c-Myc oncogenic activity is thought to be mediated in part by its ability to generate DNA replication stress and subsequent genomic instability when deregulated. Previous studies have demonstrated a nontranscriptional role for c-Myc in regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::056fa6855f15d90a3135dce0e75bb96d
http://www.sciencedirect.com/science/article/pii/S2211124713001691
http://www.sciencedirect.com/science/article/pii/S2211124713001691
Autor:
David N. Fredricks, A. Pascale, Olivier Hyrien, D.J. Valint, L. Watson, Noah G. Hoffman, Seetha Srinivasan, Christine Mitchell
Publikováno v:
American Journal of Obstetrics and Gynecology. 219:642
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3201e78d5dea1d993c85972424f40d66
https://doi.org/10.1016/j.ajog.2018.10.085
https://doi.org/10.1016/j.ajog.2018.10.085
Autor:
William A. Zagorski, Erik S. Knudsen, Christopher N. Mayhew, Seetha Srinivasan, Sandy Schwemberger
Publikováno v:
Journal of Biological Chemistry. 282:23867-23877
The retinoblastoma tumor suppressor (RB) is functionally inactivated in many human cancers. Classically, RB functions to repress E2F-mediated transcription and inhibit cell cycle progression. Consequently, RB ablation leads to loss of cell cycle cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac30b304f7839ee9f998872a6ead1cb9
https://doi.org/10.1074/jbc.m700542200
https://doi.org/10.1074/jbc.m700542200
Publikováno v:
Journal of Biological Chemistry. 280:23371-23379
Fluid shear stress maintains vascular homeostasis by influencing endothelial gene expression. One mechanism by which shear stress achieves this is through the induction of transcription factors including Krüppel-like factor 2(KLF2). We have previous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::744702c3a500a15d6a310f2ac1acdc15
https://doi.org/10.1074/jbc.m413839200
https://doi.org/10.1074/jbc.m413839200
Autor:
Vimla Band, Yoshitaka Ono, Latika Singh, David E. Wazer, Hideyuki Mukai, Seetha Srinivasan, Ajay Kumar, Qingshen Gao
Publikováno v:
Journal of Biological Chemistry. 275:14824-14830
The high risk human papillomaviruses (HPVs) are associated with carcinomas of cervix and other genital tumors. Previous studies have identified two viral oncoproteins E6 and E7, which are expressed in the majority of HPV-associated carcinomas. The ab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a6fdd7c013439512215edc7fa339f65
https://doi.org/10.1074/jbc.275.20.14824
https://doi.org/10.1074/jbc.275.20.14824
Autor:
Jean Gautier, Seetha Srinivasan
Publikováno v:
Cell Cycle Checkpoints ISBN: 9781617792724
Cell cycle checkpoints are involved in the coordinated response to DNA damage and thus play a key role in maintaining genome integrity. Several model systems have been developed to study the mechanisms and complexity of checkpoint function. Here we d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a6df0e64a1b5980c6924eff862e184a
https://doi.org/10.1007/978-1-61779-273-1_10
https://doi.org/10.1007/978-1-61779-273-1_10
Autor:
Snorri S. Thorgeirsson, Kathryn A. Wikenheiser-Brokamp, Charlene R. Sexton, Ju Seog Lee, Gregory P. Boivin, Christopher A. Reed, Xiangdong Liu, Scott L. Carter, Seetha Srinivasan, Erik S. Knudsen, Christopher N. Mayhew, Sejal R. Fox, Bruce J. Aronow
Publikováno v:
Gastroenterology. 133(3)
Background & Aims: The retinoblastoma (RB) tumor suppressor is functionally inactivated in most hepatocellular carcinomas (HCC), although the mechanisms by which RB suppresses liver tumorigenesis are poorly defined. We investigated the impact of RB l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b125dc287cdadf4b227db54264d3e54d
https://pubmed.ncbi.nlm.nih.gov/17854601
https://pubmed.ncbi.nlm.nih.gov/17854601
Publikováno v:
Biochemistry. 44(33)
Kruppel-like transcription factor 2 (KLF2), a critical gene for mouse embryogenesis, was recently identified as an inhibitor of adipogenesis. However, it is still unknown whether KLF2 is a natural repressor of adipocyte differentiation and if KLF2 af
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e6217056f1f6415c39c3fbe308d1cbf
https://pubmed.ncbi.nlm.nih.gov/16101293
https://pubmed.ncbi.nlm.nih.gov/16101293
Publikováno v:
Biological Chemistry. 385
Fluid shear stress is crucial for maintenance of a properly functioning endothelium. In this study we demonstrate that the KLF2 transcription factor is greatly induced by pulsatile shear stress in murine microvascular endothelial cells. The promoter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77d3be2a895afd6d0c44269997d9174e
https://doi.org/10.1515/bc.2004.088
https://doi.org/10.1515/bc.2004.088
Autor:
Seetha Srinivasan, Georg F. Weber, Yongtong Zhao, Hamid Band, Gaoyuan Meng, Laurie M. Delmolino, David E. Wazer, Ajay Kumar, Qingshen Gao, Mu Sheng Zeng, Goberdhan P. Dimri, Vimla Band
Publikováno v:
Molecular and cellular biology. 22(16)
High-risk human papillomaviruses (HPVs) are associated with carcinomas of the cervix and other genital tumors. The HPV oncoprotein E6 is essential for oncogenic transformation. We identify here hADA3, human homologue of the yeast transcriptional coac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c55c5482e4eed4808288457b55a7c0d
https://pubmed.ncbi.nlm.nih.gov/12138191
https://pubmed.ncbi.nlm.nih.gov/12138191