Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Seetha Mannepalli"'
Autor:
Shuwa Xu, Alina P. Sergeeva, Phinikoula S. Katsamba, Seetha Mannepalli, Fabiana Bahna, Jude Bimela, S. Lawrence Zipursky, Lawrence Shapiro, Barry Honig, Kai Zinn
Publikováno v:
Cell Reports, Vol 39, Iss 1, Pp 110618- (2022)
Summary: Neurons in the developing brain express many different cell adhesion molecules (CAMs) on their surfaces. CAM-binding affinities can vary by more than 200-fold, but the significance of these variations is unknown. Interactions between the imm
Externí odkaz:
https://doaj.org/article/f89dc971c1d84cf2a7121d9388e742ec
Autor:
Kerry Marie Goodman, Phinikoula S Katsamba, Rotem Rubinstein, Göran Ahlsén, Fabiana Bahna, Seetha Mannepalli, Hanbin Dan, Rosemary V Sampogna, Lawrence Shapiro, Barry Honig
Publikováno v:
eLife, Vol 11 (2022)
The stochastic expression of fewer than 60 clustered protocadherin (cPcdh) isoforms provides diverse identities to individual vertebrate neurons and a molecular basis for self-/nonself-discrimination. cPcdhs form chains mediated by alternating cis an
Externí odkaz:
https://doaj.org/article/f9b761bcb13542ab8bc955b4360d0564
Autor:
Alina P. Sergeeva, Phinikoula S. Katsamba, Filip Cosmanescu, Joshua J. Brewer, Goran Ahlsen, Seetha Mannepalli, Lawrence Shapiro, Barry Honig
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Dpr (Defective proboscis extension response) and DIP (Dpr Interacting Proteins) are immunoglobulin-like cell-cell adhesion proteins that form highly specific pairwise interactions, which control synaptic connectivity during Drosophila development. He
Externí odkaz:
https://doaj.org/article/13350acddc38455f905089b350c9c95f
Autor:
Heike Blockus, Sebi V. Rolotti, Miklos Szoboszlay, Eugénie Peze-Heidsieck, Tiffany Ming, Anna Schroeder, Nuno Apostolo, Kristel M. Vennekens, Phinikoula S. Katsamba, Fabiana Bahna, Seetha Mannepalli, Goran Ahlsen, Barry Honig, Lawrence Shapiro, Joris de Wit, Attila Losonczy, Franck Polleux
Publikováno v:
Cell Reports, Vol 37, Iss 3, Pp 109828- (2021)
Summary: Synaptic connectivity within adult circuits exhibits a remarkable degree of cellular and subcellular specificity. We report that the axon guidance receptor Robo2 plays a role in establishing synaptic specificity in hippocampal CA1. In vivo,
Externí odkaz:
https://doaj.org/article/ca93291c525c4a8aa7c919fed9005f37
Autor:
Kerry Marie Goodman, Rotem Rubinstein, Chan Aye Thu, Seetha Mannepalli, Fabiana Bahna, Göran Ahlsén, Chelsea Rittenhouse, Tom Maniatis, Barry Honig, Lawrence Shapiro
Publikováno v:
eLife, Vol 5 (2016)
Stochastic cell-surface expression of α-, β-, and γ-clustered protocadherins (Pcdhs) provides vertebrate neurons with single-cell identities that underlie neuronal self-recognition. Here we report crystal structures of ectodomain fragments compris
Externí odkaz:
https://doaj.org/article/5d4ce16104d24b35b29a6deed02c523e
Autor:
Kerry M Goodman, Masahito Yamagata, Xiangshu Jin, Seetha Mannepalli, Phinikoula S Katsamba, Göran Ahlsén, Alina P Sergeeva, Barry Honig, Joshua R Sanes, Lawrence Shapiro
Publikováno v:
eLife, Vol 5 (2016)
Sidekick (Sdk) 1 and 2 are related immunoglobulin superfamily cell adhesion proteins required for appropriate synaptic connections between specific subtypes of retinal neurons. Sdks mediate cell-cell adhesion with homophilic specificity that underlie
Externí odkaz:
https://doaj.org/article/e9bc2f0c2f4f4a988f06dcf96cc41409
Autor:
Alina P. Sergeeva, Phinikoula S. Katsamba, Jared M. Sampson, Fabiana Bahna, Seetha Mannepalli, Nicholas C. Morano, Lawrence Shapiro, Richard A. Friesner, Barry Honig
The strength of binding between human angiotensin converting enzyme 2 (ACE2) and the receptor binding domain (RBD) of viral spike protein plays a role in the transmissibility of the SARS-CoV-2 virus. In this study we focus on a subset of RBD mutation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0d6ebde0415fe53661d44d684cbabbc
https://doi.org/10.1101/2022.08.01.502301
https://doi.org/10.1101/2022.08.01.502301
Autor:
Phinikoula S Katsamba, Kerry Marie Goodman, Rotem Rubinstein, Göran Ahlsén, Fabiana Bahna, Seetha Mannepalli, Hanbin Dan, Rosemary V Sampogna, Lawrence Shapiro, Barry Honig
Publikováno v:
eLife. 11
The stochastic expression of fewer than 60 clustered protocadherin (cPcdh) isoforms provides diverse identities to individual vertebrate neurons and a molecular basis for self-/nonself-discrimination. cPcdhs form chains mediated by alternating cis an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::410a4c4bca6cf09b42f3b5f7c6e6168f
https://doi.org/10.7554/elife.72416
https://doi.org/10.7554/elife.72416
Autor:
Filip Cosmanescu, Lawrence Shapiro, Barry Honig, Joshua J. Brewer, Seetha Mannepalli, Alina P. Sergeeva, Goran Ahlsen, Phinikoula S. Katsamba
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications
Nature Communications
Differential binding affinities among closely related protein family members underlie many biological phenomena, including cell-cell recognition. Drosophila DIP and Dpr proteins mediate neuronal targeting in the fly through highly specific protein-pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8294dc905906f3d01cf273f8a74c21ad
https://doaj.org/article/13350acddc38455f905089b350c9c95f
https://doaj.org/article/13350acddc38455f905089b350c9c95f
Autor:
Phinikoula S Katsamba, Kerry Marie Goodman, Rotem Rubinstein, Göran Ahlsén, Fabiana Bahna, Seetha Mannepalli, Hanbin Dan, Rosemary V Sampogna, Lawrence Shapiro, Barry Honig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c994db8f93f615e2b3c8fc77ca3519c
https://doi.org/10.7554/elife.72416.sa2
https://doi.org/10.7554/elife.72416.sa2