Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Seesandra V. Rajagopala"'
Autor:
Joseph Lykins, Matthew J. Moschitto, Ying Zhou, Ekaterina V. Filippova, Hoang V. Le, Tadakimi Tomita, Barbara A. Fox, David J. Bzik, Chunlei Su, Seesandra V. Rajagopala, Kristin Flores, Furio Spano, Stuart Woods, Craig W. Roberts, Cong Hua, Kamal El Bissati, Kelsey M. Wheeler, Sarah Dovgin, Stephen P. Muench, Martin McPhillie, Colin W.G. Fishwick, Wayne F. Anderson, Patricia J. Lee, Mark Hickman, Louis M. Weiss, Jitender P. Dubey, Hernan A. Lorenzi, Richard B. Silverman, Rima L. McLeod
Publikováno v:
iScience, Vol 27, Iss 1, Pp 108477- (2024)
Summary: Toxoplasma gondii causes morbidity, mortality, and disseminates widely via cat sexual stages. Here, we find T. gondii ornithine aminotransferase (OAT) is conserved across phyla. We solve TgO/GABA-AT structures with bound inactivators at 1.55
Externí odkaz:
https://doaj.org/article/4214ce2e3d344bdb89d711a4b2786ce4
Autor:
Britton A. Strickland, Seesandra V. Rajagopala, Arash Kamali, Meghan H. Shilts, Suman B. Pakala, Marina S. Boukhvalova, Shibu Yooseph, Jorge C. G. Blanco, Suman R. Das
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract The cotton rat (Sigmodon) is the gold standard pre-clinical small animal model for respiratory viral pathogens, especially for respiratory syncytial virus (RSV). However, without a reference genome or a published transcriptome, studies requi
Externí odkaz:
https://doaj.org/article/9b3242249057498baa79d3e3609ab293
Autor:
Britton A. Strickland, Mira C. Patel, Meghan H. Shilts, Helen H. Boone, Arash Kamali, Wei Zhang, Daniel Stylos, Marina S. Boukhvalova, Christian Rosas-Salazar, Shibu Yooseph, Seesandra V. Rajagopala, Jorge C. G. Blanco, Suman R. Das
Publikováno v:
Animal Microbiome, Vol 3, Iss 1, Pp 1-17 (2021)
Abstract Background The cotton rat (genus Sigmodon) is an essential small animal model for the study of human infectious disease and viral therapeutic development. However, the impact of the host microbiome on infection outcomes has not been explored
Externí odkaz:
https://doaj.org/article/8526110de20846cd9cc266bed8059356
Autor:
Meghan H. Shilts, Christian Rosas-Salazar, Britton A. Strickland, Kyle S. Kimura, Mohammad Asad, Esha Sehanobish, Michael H. Freeman, Bronson C. Wessinger, Veerain Gupta, Hunter M. Brown, Helen H. Boone, Viraj Patel, Mali Barbi, Danielle Bottalico, Meaghan O’Neill, Nadeem Akbar, Seesandra V. Rajagopala, Simon Mallal, Elizabeth Phillips, Justin H. Turner, Elina Jerschow, Suman R. Das
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2022)
BackgroundThe upper respiratory tract (URT) is the portal of entry of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and SARS-CoV-2 likely interacts with the URT microbiome. However, understanding of the associations between the URT mi
Externí odkaz:
https://doaj.org/article/9ef946a8192346939b7eb46383e33609
Autor:
Alexander Gelbard, Meghan H. Shilts, Britton Strickland, Kevin Motz, Hsiu-Wen Tsai, Helen Boone, Wonder P. Drake, Celestine Wanjalla, Paula Marincola Smith, Hunter Brown, Marisol Ramierez, James B. Atkinson, Jason Powell, John Simpson, Seesandra V. Rajagopala, Simon Mallal, Quanhu Sheng, Alexander T. Hillel, Suman R. Das
Background Idiopathic subglottic stenosis (iSGS) is a rare fibrotic disease of the proximal airway affecting adult Caucasian women nearly exclusively. Life-threatening ventilatory obstruction occurs secondary to pernicious subglottic mucosal scar. Di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff77bc1278e5859b41a50a133030a401
https://doi.org/10.21203/rs.3.rs-2945067/v1
https://doi.org/10.21203/rs.3.rs-2945067/v1
Autor:
Seesandra V. Rajagopala, Britton A. Strickland, Suman B. Pakala, Kyle S. Kimura, Meghan H. Shilts, Christian Rosas-Salazar, Hunter M. Brown, Michael H. Freeman, Bronson C. Wessinger, Veerain Gupta, Elizabeth Phillips, Simon A. Mallal, Justin H. Turner, Suman R. Das
Publikováno v:
Journal of Virology. 97
Several prior studies have shown that SARS-CoV-2 viral load can predict the likelihood of disease spread and severity. A higher detectable SARS-CoV-2 plasma viral load was associated with worse respiratory disease severity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::927e85be791bc5406f0db12bcaca618b
https://doi.org/10.1128/jvi.01478-22
https://doi.org/10.1128/jvi.01478-22
Autor:
Christian Rosas-Salazar, Kyle S. Kimura, Meghan H. Shilts, Britton A. Strickland, Michael H. Freeman, Bronson C. Wessinger, Veerain Gupta, Hunter M. Brown, Helen H. Boone, Seesandra V. Rajagopala, Justin H. Turner, Suman Ranjan Das
Publikováno v:
Microbial Genomics. 9
To date, little is known about the effect of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus responsible for the coronavirus disease 2019 (COVID-19) pandemic, on the upper respiratory tract (URT) microbiota over time. To fill
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2967e80ff914dc9a07a1ea013f8ad10d
https://doi.org/10.1099/mgen.0.000957
https://doi.org/10.1099/mgen.0.000957
Autor:
Seesandra V, Rajagopala, Britton A, Strickland, Suman B, Pakala, Kyle S, Kimura, Meghan H, Shilts, Christian, Rosas-Salazar, Hunter M, Brown, Michael H, Freeman, Bronson C, Wessinger, Veerain, Gupta, Elizabeth, Phillips, Simon A, Mallal, Justin H, Turner, Suman R, Das
Publikováno v:
bioRxiv
Little is known about the relationships between symptomatic early-time SARS-CoV-2 viral load and upper airway mucosal gene expression and immune response. To examine the association of symptomatic SARS-CoV-2 early viral load with upper airway mucosal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04bae8ffe13e2d6f3896eac94937ff07
https://doi.org/10.1101/2022.08.23.504908
https://doi.org/10.1101/2022.08.23.504908
Publikováno v:
Dig Dis
Background: Esophageal conditions result in significant morbidity and mortality worldwide. There is growing enthusiasm for discerning the role of microbiome in esophageal diseases. Conceivably, the focus has been on examining the role of local microb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37f1e1f2631afb5037e4b8cbbc38ddc8
https://doi.org/10.1159/000517736
https://doi.org/10.1159/000517736
Autor:
Anders Wallqvist, Hao Wang, Nela Zavaljevski, Vesna Memišević, Keehwan Kwon, Rembert Pieper, Seesandra V Rajagopala, Jaques Reifman
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0188071 (2017)
Coxiella burnetii is an obligate Gram-negative intracellular pathogen and the etiological agent of Q fever. Successful infection requires a functional Type IV secretion system, which translocates more than 100 effector proteins into the host cytosol
Externí odkaz:
https://doaj.org/article/74ecc693a33d4f889ad91e60fad8b8ea