Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Seesandra V Rajagopala"'
Autor:
Anders Wallqvist, Hao Wang, Nela Zavaljevski, Vesna Memišević, Keehwan Kwon, Rembert Pieper, Seesandra V Rajagopala, Jaques Reifman
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0188071 (2017)
Coxiella burnetii is an obligate Gram-negative intracellular pathogen and the etiological agent of Q fever. Successful infection requires a functional Type IV secretion system, which translocates more than 100 effector proteins into the host cytosol
Externí odkaz:
https://doaj.org/article/74ecc693a33d4f889ad91e60fad8b8ea
Autor:
Mira C Patel, Wei Wang, Lioubov M Pletneva, Seesandra V Rajagopala, Yi Tan, Tina V Hartert, Marina S Boukhvalova, Stefanie N Vogel, Suman R Das, Jorge C G Blanco
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0166336 (2016)
In recent years, there has been a significant increase in detection of Enterovirus D-68 (EV-D68) among patients with severe respiratory infections worldwide. EV-D68 is now recognized as a re-emerging pathogen; however, due to lack of a permissive ani
Externí odkaz:
https://doaj.org/article/065d7e0b51a84a78b777c7ffd4826168
Autor:
Vesna Memišević, Nela Zavaljevski, Seesandra V Rajagopala, Keehwan Kwon, Rembert Pieper, David DeShazer, Jaques Reifman, Anders Wallqvist
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 3, p e1004088 (2015)
Burkholderia pathogenicity relies on protein virulence factors to control and promote bacterial internalization, survival, and replication within eukaryotic host cells. We recently used yeast two-hybrid (Y2H) screening to identify a small set of nove
Externí odkaz:
https://doaj.org/article/a62c57576e2e4a0db0ff95e2c5454f49
Autor:
Even Fossum, Caroline C Friedel, Seesandra V Rajagopala, Björn Titz, Armin Baiker, Tina Schmidt, Theo Kraus, Thorsten Stellberger, Christiane Rutenberg, Silpa Suthram, Sourav Bandyopadhyay, Dietlind Rose, Albrecht von Brunn, Mareike Uhlmann, Christine Zeretzke, Yu-An Dong, Hélène Boulet, Manfred Koegl, Susanne M Bailer, Ulrich Koszinowski, Trey Ideker, Peter Uetz, Ralf Zimmer, Jürgen Haas
Publikováno v:
PLoS Pathogens, Vol 5, Iss 9, p e1000570 (2009)
Herpesviruses constitute a family of large DNA viruses widely spread in vertebrates and causing a variety of different diseases. They possess dsDNA genomes ranging from 120 to 240 kbp encoding between 70 to 170 open reading frames. We previously repo
Externí odkaz:
https://doaj.org/article/33021b3072d04c4e8a3b53bdf764ccc6
Autor:
Björn Titz, Seesandra V Rajagopala, Johannes Goll, Roman Häuser, Matthew T McKevitt, Timothy Palzkill, Peter Uetz
Publikováno v:
PLoS ONE, Vol 3, Iss 5, p e2292 (2008)
Protein interaction networks shed light on the global organization of proteomes but can also place individual proteins into a functional context. If we know the function of bacterial proteins we will be able to understand how these species have adapt
Externí odkaz:
https://doaj.org/article/dbb551e5739b4a99ac23900b76af434b
Autor:
Joseph Lykins, Matthew J. Moschitto, Ying Zhou, Ekaterina V. Filippova, Hoang V. Le, Tadakimi Tomita, Barbara A. Fox, David J. Bzik, Chunlei Su, Seesandra V. Rajagopala, Kristin Flores, Furio Spano, Stuart Woods, Craig W. Roberts, Cong Hua, Kamal El Bissati, Kelsey M. Wheeler, Sarah Dovgin, Stephen P. Muench, Martin McPhillie, Colin W.G. Fishwick, Wayne F. Anderson, Patricia J. Lee, Mark Hickman, Louis M. Weiss, Jitender P. Dubey, Hernan A. Lorenzi, Richard B. Silverman, Rima L. McLeod
Publikováno v:
iScience, Vol 27, Iss 1, Pp 108477- (2024)
Summary: Toxoplasma gondii causes morbidity, mortality, and disseminates widely via cat sexual stages. Here, we find T. gondii ornithine aminotransferase (OAT) is conserved across phyla. We solve TgO/GABA-AT structures with bound inactivators at 1.55
Externí odkaz:
https://doaj.org/article/4214ce2e3d344bdb89d711a4b2786ce4
Autor:
Britton A. Strickland, Seesandra V. Rajagopala, Arash Kamali, Meghan H. Shilts, Suman B. Pakala, Marina S. Boukhvalova, Shibu Yooseph, Jorge C. G. Blanco, Suman R. Das
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract The cotton rat (Sigmodon) is the gold standard pre-clinical small animal model for respiratory viral pathogens, especially for respiratory syncytial virus (RSV). However, without a reference genome or a published transcriptome, studies requi
Externí odkaz:
https://doaj.org/article/9b3242249057498baa79d3e3609ab293
Autor:
Britton A. Strickland, Mira C. Patel, Meghan H. Shilts, Helen H. Boone, Arash Kamali, Wei Zhang, Daniel Stylos, Marina S. Boukhvalova, Christian Rosas-Salazar, Shibu Yooseph, Seesandra V. Rajagopala, Jorge C. G. Blanco, Suman R. Das
Publikováno v:
Animal Microbiome, Vol 3, Iss 1, Pp 1-17 (2021)
Abstract Background The cotton rat (genus Sigmodon) is an essential small animal model for the study of human infectious disease and viral therapeutic development. However, the impact of the host microbiome on infection outcomes has not been explored
Externí odkaz:
https://doaj.org/article/8526110de20846cd9cc266bed8059356
Autor:
Alexander Gelbard, Meghan H. Shilts, Britton Strickland, Kevin Motz, Hsiu-Wen Tsai, Helen Boone, Wonder P. Drake, Celestine Wanjalla, Paula Marincola Smith, Hunter Brown, Marisol Ramierez, James B. Atkinson, Jason Powell, John Simpson, Seesandra V. Rajagopala, Simon Mallal, Quanhu Sheng, Alexander T. Hillel, Suman R. Das
Background Idiopathic subglottic stenosis (iSGS) is a rare fibrotic disease of the proximal airway affecting adult Caucasian women nearly exclusively. Life-threatening ventilatory obstruction occurs secondary to pernicious subglottic mucosal scar. Di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff77bc1278e5859b41a50a133030a401
https://doi.org/10.21203/rs.3.rs-2945067/v1
https://doi.org/10.21203/rs.3.rs-2945067/v1
Autor:
Seesandra V. Rajagopala, Britton A. Strickland, Suman B. Pakala, Kyle S. Kimura, Meghan H. Shilts, Christian Rosas-Salazar, Hunter M. Brown, Michael H. Freeman, Bronson C. Wessinger, Veerain Gupta, Elizabeth Phillips, Simon A. Mallal, Justin H. Turner, Suman R. Das
Publikováno v:
Journal of Virology. 97
Several prior studies have shown that SARS-CoV-2 viral load can predict the likelihood of disease spread and severity. A higher detectable SARS-CoV-2 plasma viral load was associated with worse respiratory disease severity.