Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Seergazhi G. Srivatsan"'
Publikováno v:
ACS Omega, Vol 3, Iss 11, Pp 15343-15352 (2018)
Externí odkaz:
https://doaj.org/article/0dce61b558884294b266b1892417fec0
Autor:
Saddam Y. Khatik, Sruthi Sudhakar, Satyajit Mishra, Jeet Kalia, P. I. Pradeepkumar, Seergazhi G. Srivatsan
Publikováno v:
Chemical Science. 14:5627-5637
We report the use of a new dual-app nucleoside probe composed of environment-sensitive fluorescent and 19F NMR labels in dissecting the structural polymorphism of G-quadruplexes formed by the EGFR gene, which is implicated in many cancers.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf143cd9dd89220edcf91a903d404007
https://doi.org/10.1039/d3sc00519d
https://doi.org/10.1039/d3sc00519d
Publikováno v:
Bioconjugate Chemistry. 33:1515-1526
Although evidence for the existence and biological role of i-motif (iM) DNA structures in cells is emerging, probing their structural polymorphism and identifying physiologically active conformations using currently available tools remain a major cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4cf5274bf38de2f10aedabcc92201c0
https://doi.org/10.1021/acs.bioconjchem.2c00237
https://doi.org/10.1021/acs.bioconjchem.2c00237
Autor:
Pulak Ghosh, Heike M. Kropp, Karin Betz, Samra Ludmann, Kay Diederichs, Andreas Marx, Seergazhi G. Srivatsan
Publikováno v:
Journal of the American Chemical Society. 144(23)
DNA polymerases can process a wide variety of structurally diverse nucleotide substrates, but the molecular basis by which the analogs are processed is not completely understood. Here, we demonstrate the utility of environment-sensitive heterocycle-m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0322af38656733164bd03975a94922a4
https://pubmed.ncbi.nlm.nih.gov/35666775
https://pubmed.ncbi.nlm.nih.gov/35666775
Autor:
Jerrin Thomas George, Debojyoti Chakraborty, Souvik Maiti, Seergazhi G. Srivatsan, Meghali Aich, Dipanjali Sinha, Mohd Azhar, Uddhav B. Ambi
Publikováno v:
J Am Chem Soc
Locus-specific interrogation of target genes employing functional probes such as proteins and small molecules is paramount in decoding the molecular basis of gene function and designing tools to modulate its downstream effects. In this context, CRISP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eff27530ea86f3fa688dfb49f0849bb
https://doi.org/10.1021/jacs.0c06541
https://doi.org/10.1021/jacs.0c06541
Publikováno v:
Nanoscale advances
Analogous to nucleic acids, the building blocks of nucleic acids and their derivatives are widely used to create supramolecular architectures for application mainly in the field of biomedicine. Here, we describe the construction of a multi-stimuli re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d666fd887f6d9798fda6e4b12432add
http://europepmc.org/articles/PMC7611312
http://europepmc.org/articles/PMC7611312
Publikováno v:
Chem Commun (Camb)
To understand the structure and ensuing function of RNA in various cellular processes, researchers greatly rely on traditional as well as contemporary labeling technologies to devise efficient biochemical and biophysical platforms. In this context, b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f70a4255becab54ab630110da0605e41
https://doi.org/10.1039/d0cc05228k
https://doi.org/10.1039/d0cc05228k
Publikováno v:
Chem Asian J
Nucleoside-lipid conjugates are very useful supramolecular building blocks to construct self-assembled architectures suited for biomedical and material applications. Such nucleoside derivatives can be further synthetically manipulated to endow additi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cb5f7c288f34aaa9dac59c7a0b691e9
https://europepmc.org/articles/PMC7612753/
https://europepmc.org/articles/PMC7612753/
Publikováno v:
Chembiochem
Development of versatile probes that would enable study different conformations and recognition properties of therapeutic nucleic acid motifs by complementing biophysical techniques can greatly aid nucleic acid analysis and therapy. Here, we report t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9df60d7687211c87ed0266d3759201f9
https://europepmc.org/articles/PMC7612754/
https://europepmc.org/articles/PMC7612754/
Publikováno v:
Molecular Architectonics and Nanoarchitectonics ISBN: 9789811641886
Molecular Architectonics and Nanoarchitectonics
Molecular Architectonics and Nanoarchitectonics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ed0263f8a7e0380fc8a1204fd61dd3c
https://doi.org/10.1007/978-981-16-4189-3_13
https://doi.org/10.1007/978-981-16-4189-3_13