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pro vyhledávání: '"Seepersad, Colin"'
Autor:
Seepersad, Colin Elliott
Transient Receptor Potential Melastatin 2 (TRPM2) is a widely expressed, non-selective cationic channel with implicated roles in cell death, chemokine production and oxidative stress. This study characterizes a novel interactor of TRPM2. Using fusion
Externí odkaz:
http://hdl.handle.net/1807/31435
Autor:
Rajasekar, Karthik V., Zdanowski, Konrad, Yan, Jun, Hopper, Jonathan T. S., Francis, Marie-Louise R., Seepersad, Colin, Sharp, Connor, Pecqueur, Ludovic, Werner, Jörn M., Robinson, Carol V., Mohammed, Shabaz, Potts, Jennifer R., Kleanthous, Colin
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Nature Communications
Nature Communications
Redox-regulated effector systems that counteract oxidative stress are essential for all forms of life. Here we uncover a new paradigm for sensing oxidative stress centred on the hydrophobic core of a sensor protein. RsrA is an archetypal zinc-binding