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Autor:
Jill D. Bashutski, Morris F. Manolson, S. Jeffrey Dixon, Stephen M. Sims, Johan N. M. Heersche, Seema Shorey, Azza Gramoun
Publikováno v:
Physiology and Pharmacology Publications
The integrin alphavbeta3 mediates cell-matrix interactions. Vitaxin(R), a humanized monoclonal antibody that blocks human and rabbit alphavbeta3 integrins, is in clinical trials for metastatic melanoma and prostate cancer. alphavbeta3 is the predomin