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Statistically Optimized Facile Development, Characterization and Evaluation of Niosomal Nasal Drug Delivery System of Ropinirole Hydrochloride: In vitro Drug Release, Cytotoxicity and ex vivo Permeability Studies

Autor: Regulagadda Suryanarayana, Anjaneyulu Vinukonda, Seema Saroj, Neelu Jain, Harish Pandey, VSA Pavan Rudrabhatla, Thrimurthulu Gode

Publikováno v: Indian Journal of Pharmaceutical Education and Research. 57:62-73

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f506982a1f0dbcc080b5c86ce605cc67
https://doi.org/10.5530/001954641874

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Development and Validation of an Environmentally Benign and Robust Stability Indicating Assay Method for Lenalidomide: Comprehensive Degradation Kinetics Study and Application of Synergistic Approach Involving Green Analytical Chemistry and Quality by Des

Autor: Seema Saroj, Sadhana J. Rajput, Priya V. Shah, Juhi Saxena

Publikováno v: Indian Journal of Pharmaceutical Education and Research. 53:133-143

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dc5b8518a1e1c3ebd05c62b01678f193
https://doi.org/10.5530/ijper.53.1.18

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Etoposide encased folic acid adorned mesoporous silica nanoparticles as potent nanovehicles for enhanced prostate cancer therapy: synthesis, characterization, cellular uptake and biodistribution

Autor: Seema Saroj, Sadhana J. Rajput

Publikováno v: Artificial Cells, Nanomedicine, and Biotechnology. 46:1115-1130

The present research was motivated by the dire need to design a targeted and safe Nano-vehicle for delivery of Etoposide (ETE), which would be tolerant of normal cells and exclusively toxic to prostate cancer cells. The folic acid functionalized meso

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::735904321b9e9540725592ef7fb36524
https://doi.org/10.1080/21691401.2018.1533843

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Green Analytical Chemistry and Quality by Design: A Combined approach towards Robust and Sustainable Modern Analysis

Autor: Vinod Jairaj, Rajeshwari Rathod, Priya Shah, Seema Saroj

Publikováno v: Current Analytical Chemistry. 14:367-381

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4ac93943efb547f57b306eff5c9f5570
https://doi.org/10.2174/1573411013666170615140836

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Composite smart mesoporous silica nanoparticles as promising therapeutic and diagnostic candidates: Recent trends and applications

Autor: Seema Saroj, Sadhana J. Rajput

Publikováno v: Journal of Drug Delivery Science and Technology. 44:349-365

Theranostics is an emerging field which involves application of a single formulation for both diagnosis as well as therapeutics. The present manuscript describes various applications of hybrid mesoporous silica nanoparticles in therapeutics, diagnost

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ffa2e32a5b04d6a4a5305323d7131e3d
https://doi.org/10.1016/j.jddst.2018.01.014

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Etoposide encapsulated functionalized mesoporous silica nanoparticles: Synthesis, characterization and effect of functionalization on dissolution kinetics in simulated and biorelevant media

Autor: Sadhana J. Rajput, Seema Saroj

Publikováno v: Journal of Drug Delivery Science and Technology. 44:27-40

Highly ordered hexagonal (MCM-41) mesoporous silica nanoparticles (MSNs) loaded with etoposide (ETO) were synthesized and functionalized with amino groups (MCM-41-A). The objective was to investigate effect of functionalization and compare release pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0f2ec4eedfbac1340f29557b79c93648
https://doi.org/10.1016/j.jddst.2017.11.020

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Applying green analytical chemistry for development and validation of RP-HPLC stability indicating assay method for estimation of fenoverine in bulk and dosage form using quality by design approach

Autor: Seema Saroj, Rajeshwari Rathod, Vinod Jairaj

Publikováno v: Journal of Liquid Chromatography & Related Technologies. 40:340-352

A green and robust reverse-phase liquid chromatographic method has been developed for the determination of fenoverine (FEN), by applying combined principles of green analytical chemistry and qualit...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::749d860741add41deb68553396a30425
https://doi.org/10.1080/10826076.2017.1304414

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Facile development, characterization, and evaluation of novel bicalutamide loaded pH-sensitive mesoporous silica nanoparticles for enhanced prostate cancer therapy

Autor: Sadhana J. Rajput, Seema Saroj

Publikováno v: Drug development and industrial pharmacy. 45(4)

It is a challenge to deliver therapeutics exclusively to cancer cells, while sparing the normal cells. However, pH-sensitive delivery systems have proved to be highly efficient in fulfilling this task due to their ability to provide on-demand and sel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86664ff165e3a735d8ec7f1d74b6551b
https://pubmed.ncbi.nlm.nih.gov/30582382

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ESTIMATION OF LENALIDOMIDE IN BULK AND ITS DOSAGE FORM USING UV SPECTROPHOTOMETRIC AND RP-HPLC METHODS

Autor: Juhi Saxena, Seema Saroj

The present work includes a simple, economic, rapid, accurate and precise UV spectrophotometric and isocratic RP-HPLC method development for estimation of Lenalidomide in bulk and its formulation. Estimation was done at 250nm which was found to be λ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aa268797ed57088599811b20b9e9b4f

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