Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Seema Rawal"'
Autor:
Faye M Johnson, Filip Janku, Mohamed A Gouda, Hai T Tran, Jitesh D Kawedia, Debora Schmitz, Hendrik Streefkerk, J Jack Lee, Clark R Andersen, Defeng Deng, Seema Rawal, Pooja A Shah, Adel K El-Naggar, Jason M Johnson, Mitchell J Frederick
Publikováno v:
The Oncologist. 27:1004-e926
Background PI3K/mTOR inhibition leads to apoptosis of NOTCH1-mutant head and neck squamous cell carcinoma (HNSCC) cells. We tested the efficacy of the PI3K/mTOR inhibitor bimiralisib in patients with NOTCH1-mutant HNSCC. Methods Patients with recurre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::230b44ce16fbf708715ec0621a79cd8a
https://doi.org/10.1093/oncolo/oyac185
https://doi.org/10.1093/oncolo/oyac185
Autor:
David J. Delgado, Tina Chou, Rakesh Sharma, Fuliang Chu, Nathan Fowler, Amber U Luong, Sattva S. Neelapu, Hyun Jun Park, Francisco Vega, Min Zhang, Seema Rawal, R. Eric Davis, Heather Lin, Shibichakravarthy Kannan, Veerabhadran Baladandayuthapani, Durga Nattamai, Chen Dong
Publikováno v:
The Journal of Immunology. 190:6681-6693
The microenvironment of human follicular lymphoma (FL), an incurable B cell non-Hodgkin’s lymphoma, is thought to play a major role in its pathogenesis and course. Microenvironmental cells of likely importance include follicular Th cells (TFH) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9cb26ced6d280d0c53250755cfbf4a3
https://doi.org/10.4049/jimmunol.1201363
https://doi.org/10.4049/jimmunol.1201363
Publikováno v:
Journal of Neuroscience Research. 87:218-227
The microsomal epoxide hydrolase (mEH) and soluble epoxide hydrolase (sEH) enzymes exist in a variety of cells and tissues, including liver, kidney and testis. However, very little is known about brain epoxide hydrolases. Here we report the expressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a171fcf6679f9a802e372c658102460
https://doi.org/10.1002/jnr.21827
https://doi.org/10.1002/jnr.21827
Autor:
Sattva S. Neelapu, Loretta J. Nastoupil, Francesco Turturro, Larry W. Kwak, Yasuhiro Oki, Seema Rawal, Robert Z. Orlowski, Jatin P. Shah, R. Eric Davis, Veerabhadran Baladandayuthapani, Kenneth Y. Tsai, Fredrick B. Hagemeister, Michelle A. Fanale, Linda Claret, Peter McLaughlin, Felipe Samaniego, Lei Feng, Nathan Fowler, Tariq Muzzafar, Jason R. Westin, Jorge E. Romaguera, Luis Fayad, Michael Wang
Summary Background Standard treatments for indolent non-Hodgkin lymphomas are often toxic, and most patients ultimately relapse. Lenalidomide, an immunomodulatory agent, is effective as monotherapy for relapsed indolent non-Hodgkin lymphoma. We asses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4e7d38c79178443881dcfc20c3e6dda
https://europepmc.org/articles/PMC4370362/
https://europepmc.org/articles/PMC4370362/
Autor:
Harry W. Schroeder, Soung Chul Cha, Jinsong Wei, Amber U Luong, Juliana Ong, Seema Rawal, Shibichakravarthy Kannan, Weiguo Wu, Benjamin Kwak, Kunhwa Kim, Sang Kim, Flavio Egidio Baio, Daniel S. Paick, Michael Popescu, Larry W. Kwak, Sattva S. Neelapu, Richard E. Davis, Leticia S. Watkins, Hong Qin
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 190(9)
Antigen activation of the B-cell receptor (BCR) may play a role in the pathogenesis of human follicular lymphoma (FL) and other B-cell malignancies. However, the nature of the antigen(s) recognized by tumor BCRs has not been well studied. Here, we us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abd14fd1f86e2674bb7f1e796e5173fe
https://pubmed.ncbi.nlm.nih.gov/23536634
https://pubmed.ncbi.nlm.nih.gov/23536634
Autor:
Larry W. Kwak, Jinsheng Weng, Jorge E. Romaguera, Hyun Jun Park, Rakesh Sharma, Fuliang Chu, David A. Delgado, Luis Fayad, Michelle A. Fanale, Amber U Luong, Seema Rawal, Sattva S. Neelapu
Publikováno v:
Blood. 120(8)
Immunotherapy with therapeutic idiotype vaccines offers promise for treatment of B-cell malignancies. However, identification of novel immunogenic lymphoma-associated antigens that are universally expressed is necessary to overcome the barriers of pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b8c4861c396e4a40e879e2b3b39f8fe
https://pubmed.ncbi.nlm.nih.gov/22918421
https://pubmed.ncbi.nlm.nih.gov/22918421
Autor:
Hui Min Fan, Yeonseok Chung, Hoyong Lim, Xiao Hui Zhou, Yi Hong Wang, Fuliang Chu, Shinya Tanaka, Roza Nurieva, Chen Dong, Joseph M. Reynolds, Sattva S. Neelapu, Zhong Ming Liu, Seema Rawal, Gustavo J. Martinez
Publikováno v:
Nature medicine
Foxp3(+) regulatory T (T(reg)) cells suppress different types of immune responses to help maintain homeostasis in the body. How T(reg) cells regulate humoral immunity, including germinal center reactions, is unclear. Here we identify a subset of T(re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ef2675cffbdfa6059eeb0649b9d5649
https://pubmed.ncbi.nlm.nih.gov/21970029
https://pubmed.ncbi.nlm.nih.gov/21970029
Publikováno v:
The FASEB Journal. 22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14dfced4e856a430db085203d788685f
https://doi.org/10.1096/fasebj.22.1_supplement.479.4
https://doi.org/10.1096/fasebj.22.1_supplement.479.4
Publikováno v:
Molecular and cellular biochemistry. 268(1-2)
Amoebiasis caused by the protozoan parasite Entamoeba histolytica is one of the leading parasitic causes of morbidity and mortality in the developing countries. Among the variety of virulence factors, an adherence lectin (Gal/GalNAc, 260 kDa) has bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::946c415523c4f712be7091f3fee8d294
https://pubmed.ncbi.nlm.nih.gov/15724442
https://pubmed.ncbi.nlm.nih.gov/15724442
Autor:
Nathan Fowler, Sattva S. Neelapu, Seema Rawal, Michael J. Wallace, David J. Delgado, R. Eric Davis, Min Zhang, Rakesh Sharma, Tariq Muzzafar, Linda Catherine Lacerte, Veerabhadran Baladandayuthapani, Felipe Samaniego, Nusrat Harun, Carla Heise, Zhiqiang Wang
Publikováno v:
Blood. 120:2766-2766
Abstract 2766 Background: Lenalidomide plus rituximab therapy is a highly effective and well-tolerated therapy in patients (pts) with follicular lymphoma (FL). In a Phase II trial, this combination induced a complete remission rate of 87% in pts with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a0ffc2e0c7ba17f890f106fde32e3f2
https://doi.org/10.1182/blood.v120.21.2766.2766
https://doi.org/10.1182/blood.v120.21.2766.2766