Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Seema Mukhija"'
Autor:
Henk Schulz, Monica Bandera, Laurent Weiss, Christian Oefner, Sergio Lociuro, Heike Laue, Glenn E. Dale, Sandro Parisi, Seema Mukhija, Andreas Haldimann
Publikováno v:
Journal of Antimicrobial Chemotherapy. 63:687-698
Objectives Iclaprim is a novel 2,4-diaminopyrimidine that exhibits potent, rapid bactericidal activity against major Gram-positive pathogens, including methicillin-susceptible Staphylococcus aureus and methicillin-resistant S. aureus, and is currentl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::360cbedbac9234e0e180a3b32c35fbdc
https://doi.org/10.1093/jac/dkp024
https://doi.org/10.1093/jac/dkp024
Publikováno v:
Microbiology. 149:2645-2652
The phosphoenolpyruvate : sugar phosphotransferase system (PTS) catalyses translocation with concomitant phosphorylation of sugars and hexitols and it regulates metabolism in response to the availability of carbohydrates. The PTS forms an interface b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26fe62b7ccd09c7d5ef5767c06f17ca1
https://doi.org/10.1099/mic.0.26406-0
https://doi.org/10.1099/mic.0.26406-0
Publikováno v:
Journal of Computer-Aided Molecular Design. 15:103-115
Starting from the NMR structure of the binary complex between the N-terminal domain of the unphosphorylated enzyme I (EIN) of the phosphoenolpyruvate:sugar phosphotransferase (PTS) and the histidine-containing phosphocarrier protein (HPr), a molecula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8bf635a21cf60919baf88c5bd6edcf6a
https://doi.org/10.1023/a:1008145813315
https://doi.org/10.1023/a:1008145813315
Publikováno v:
Bioorganicmedicinal chemistry letters. 14(24)
A series of isoxazole-3-hydroxamic acid derivatives has been identified as a new class of small, nonpeptidic inhibitors of peptide deformylase (PDF). The synthesis, enzyme inhibition and preliminary investigation of the binding mode of this potential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e30d85f5a4d1ec22e1fde4f0735492d
https://pubmed.ncbi.nlm.nih.gov/15546716
https://pubmed.ncbi.nlm.nih.gov/15546716
Publikováno v:
European journal of biochemistry. 254(2)
The phosphoenolpyruvate(P-pyruvate)-dependent sugar phosphotransferase system (PTS) is a transport and signal-transduction system which is almost ubiquitous in bacteria but does not occur in eucaryotes. It catalyzes the uptake and phosphorylation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5d84fe4d70c330eb840a830b0c588fe
https://pubmed.ncbi.nlm.nih.gov/9660202
https://pubmed.ncbi.nlm.nih.gov/9660202
Autor:
Bernhard Erni, Seema Mukhija
Publikováno v:
Molecular microbiology. 25(6)
The bacterial phosphoenolpyruvate-sugar phosphotransferase system (PTS) mediates the uptake and phosphorylation of carbohydrates and is involved in signal transduction. In response to the availability of carbohydrates it modulates catabolite repressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fd8f650b960970dcef605027e8b22ed
https://pubmed.ncbi.nlm.nih.gov/9350871
https://pubmed.ncbi.nlm.nih.gov/9350871
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 15:2421
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02b80cd9ea68897bbd3b9ca737345e6f
https://doi.org/10.1016/j.bmcl.2005.03.001
https://doi.org/10.1016/j.bmcl.2005.03.001
Autor:
Christian Oefner, Monica Bandera, Andreas Haldimann, Heike Laue, Henk Schulz, Seema Mukhija, Sandro Parisi, Laurent Weiss, Sergio Lociuro, Glenn E. Dale
Publikováno v:
Journal of Antimicrobial Chemotherapy (JAC); Apr2009, Vol. 63 Issue 4, p687-687, 1p